BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

212 related articles for article (PubMed ID: 12376107)

  • 1. SEK1/MKK4-mediated SAPK/JNK signaling participates in embryonic hepatoblast proliferation via a pathway different from NF-kappaB-induced anti-apoptosis.
    Watanabe T; Nakagawa K; Ohata S; Kitagawa D; Nishitai G; Seo J; Tanemura S; Shimizu N; Kishimoto H; Wada T; Aoki J; Arai H; Iwatsubo T; Mochita M; Watanabe T; Satake M; Ito Y; Matsuyama T; Mak TW; Penninger JM; Nishina H; Katada T
    Dev Biol; 2002 Oct; 250(2):332-47. PubMed ID: 12376107
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Defective liver formation and liver cell apoptosis in mice lacking the stress signaling kinase SEK1/MKK4.
    Nishina H; Vaz C; Billia P; Nghiem M; Sasaki T; De la Pompa JL; Furlonger K; Paige C; Hui C; Fischer KD; Kishimoto H; Iwatsubo T; Katada T; Woodgett JR; Penninger JM
    Development; 1999 Feb; 126(3):505-16. PubMed ID: 9876179
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Prevention of hepatic apoptosis and embryonic lethality in RelA/TNFR-1 double knockout mice.
    Rosenfeld ME; Prichard L; Shiojiri N; Fausto N
    Am J Pathol; 2000 Mar; 156(3):997-1007. PubMed ID: 10702415
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Impaired CD28-mediated interleukin 2 production and proliferation in stress kinase SAPK/ERK1 kinase (SEK1)/mitogen-activated protein kinase kinase 4 (MKK4)-deficient T lymphocytes.
    Nishina H; Bachmann M; Oliveira-dos-Santos AJ; Kozieradzki I; Fischer KD; Odermatt B; Wakeham A; Shahinian A; Takimoto H; Bernstein A; Mak TW; Woodgett JR; Ohashi PS; Penninger JM
    J Exp Med; 1997 Sep; 186(6):941-53. PubMed ID: 9294148
    [TBL] [Abstract][Full Text] [Related]  

  • 5. SEK1 deficiency reveals mitogen-activated protein kinase cascade crossregulation and leads to abnormal hepatogenesis.
    Ganiatsas S; Kwee L; Fujiwara Y; Perkins A; Ikeda T; Labow MA; Zon LI
    Proc Natl Acad Sci U S A; 1998 Jun; 95(12):6881-6. PubMed ID: 9618507
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Activation mechanism and physiological roles of stress-activated protein kinase/c-Jun NH2-terminal kinase in mammalian cells.
    Nishina H; Nakagawa K; Azuma N; Katada T
    J Biol Regul Homeost Agents; 2003; 17(4):295-302. PubMed ID: 15065757
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Impaired synergistic activation of stress-activated protein kinase SAPK/JNK in mouse embryonic stem cells lacking SEK1/MKK4: different contribution of SEK2/MKK7 isoforms to the synergistic activation.
    Wada T; Nakagawa K; Watanabe T; Nishitai G; Seo J; Kishimoto H; Kitagawa D; Sasaki T; Penninger JM; Nishina H; Katada T
    J Biol Chem; 2001 Aug; 276(33):30892-7. PubMed ID: 11418587
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Stress-signalling kinase Sek1 protects thymocytes from apoptosis mediated by CD95 and CD3.
    Nishina H; Fischer KD; Radvanyi L; Shahinian A; Hakem R; Rubie EA; Bernstein A; Mak TW; Woodgett JR; Penninger JM
    Nature; 1997 Jan; 385(6614):350-3. PubMed ID: 9002521
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Activation of c-Jun NH2-terminal kinase/stress-activated protein kinase (JNK/SAPK) is critical for hypoxia-induced apoptosis of human malignant melanoma.
    Kunz M; Ibrahim S; Koczan D; Thiesen HJ; Köhler HJ; Acker T; Plate KH; Ludwig S; Rapp UR; Bröcker EB; van Muijen GN; Flory E; Gross G
    Cell Growth Differ; 2001 Mar; 12(3):137-45. PubMed ID: 11306514
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Stress pathway activation induces phosphorylation of retinoid X receptor.
    Lee HY; Suh YA; Robinson MJ; Clifford JL; Hong WK; Woodgett JR; Cobb MH; Mangelsdorf DJ; Kurie JM
    J Biol Chem; 2000 Oct; 275(41):32193-9. PubMed ID: 10938283
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Different properties of SEK1 and MKK7 in dual phosphorylation of stress-induced activated protein kinase SAPK/JNK in embryonic stem cells.
    Kishimoto H; Nakagawa K; Watanabe T; Kitagawa D; Momose H; Seo J; Nishitai G; Shimizu N; Ohata S; Tanemura S; Asaka S; Goto T; Fukushi H; Yoshida H; Suzuki A; Sasaki T; Wada T; Penninger JM; Nishina H; Katada T
    J Biol Chem; 2003 May; 278(19):16595-601. PubMed ID: 12624093
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Physiological roles of SAPK/JNK signaling pathway.
    Nishina H; Wada T; Katada T
    J Biochem; 2004 Aug; 136(2):123-6. PubMed ID: 15496581
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Dynamic expression of SEK1 suggests multiple roles of the gene during embryogenesis and in adult brain of mice.
    Lee JK; Hwang WS; Lee YD; Han PL
    Brain Res Mol Brain Res; 1999 Mar; 66(1-2):133-40. PubMed ID: 10095085
    [TBL] [Abstract][Full Text] [Related]  

  • 14. TRAF2 is essential for TNF-alpha-induced osteoclastogenesis.
    Kanazawa K; Kudo A
    J Bone Miner Res; 2005 May; 20(5):840-7. PubMed ID: 15824857
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Kinase suppressor of Ras determines survival of intestinal epithelial cells exposed to tumor necrosis factor.
    Yan F; John SK; Polk DB
    Cancer Res; 2001 Dec; 61(24):8668-75. PubMed ID: 11751383
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cell-type-specific activation of p38 protein kinase cascades by the novel tumor promoter palytoxin.
    Li S; Wattenberg EV
    Toxicol Appl Pharmacol; 1999 Oct; 160(2):109-19. PubMed ID: 10527909
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Multiple signaling pathways for the activation of JNK in mast cells: involvement of Bruton's tyrosine kinase, protein kinase C, and JNK kinases, SEK1 and MKK7.
    Kawakami Y; Hartman SE; Holland PM; Cooper JA; Kawakami T
    J Immunol; 1998 Aug; 161(4):1795-802. PubMed ID: 9712046
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Distinct mechanisms target stress and extracellular signal-activated kinase 1 and Jun N-terminal kinase during infection of macrophages with Salmonella.
    Procyk KJ; Rippo MR; Testi R; Hoffmann F; Parker PJ; Baccarini M
    J Immunol; 1999 Nov; 163(9):4924-30. PubMed ID: 10528195
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The stress kinase mitogen-activated protein kinase kinase (MKK)7 is a negative regulator of antigen receptor and growth factor receptor-induced proliferation in hematopoietic cells.
    Sasaki T; Wada T; Kishimoto H; Irie-Sasaki J; Matsumoto G; Goto T; Yao Z; Wakeham A; Mak TW; Suzuki A; Cho SK; Zuniga-Pflucker JC; Oliveira-dos-Santos AJ; Katada T; Nishina H; Penninger JM
    J Exp Med; 2001 Sep; 194(6):757-68. PubMed ID: 11560992
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Activated Ki-Ras suppresses 12-O-tetradecanoylphorbol-13-acetate-induced activation of the c-Jun NH2-terminal kinase pathway in human colon cancer cells.
    Okumura K; Shirasawa S; Nishioka M; Sasazuki T
    Cancer Res; 1999 May; 59(10):2445-50. PubMed ID: 10344756
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.