These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

686 related articles for article (PubMed ID: 12376477)

  • 1. Tangeretin induces cell-cycle G1 arrest through inhibiting cyclin-dependent kinases 2 and 4 activities as well as elevating Cdk inhibitors p21 and p27 in human colorectal carcinoma cells.
    Pan MH; Chen WJ; Lin-Shiau SY; Ho CT; Lin JK
    Carcinogenesis; 2002 Oct; 23(10):1677-84. PubMed ID: 12376477
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of cyclin-dependent kinases 2 and 4 activities as well as induction of Cdk inhibitors p21 and p27 during growth arrest of human breast carcinoma cells by (-)-epigallocatechin-3-gallate.
    Liang YC; Lin-Shiau SY; Chen CF; Lin JK
    J Cell Biochem; 1999 Oct; 75(1):1-12. PubMed ID: 10462699
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Induction of G1 phase arrest in MCF human breast cancer cells by pentagalloylglucose through the down-regulation of CDK4 and CDK2 activities and up-regulation of the CDK inhibitors p27(Kip) and p21(Cip).
    Chen WJ; Chang CY; Lin JK
    Biochem Pharmacol; 2003 Jun; 65(11):1777-85. PubMed ID: 12781329
    [TBL] [Abstract][Full Text] [Related]  

  • 4. G1 phase accumulation induced by UCN-01 is associated with dephosphorylation of Rb and CDK2 proteins as well as induction of CDK inhibitor p21/Cip1/WAF1/Sdi1 in p53-mutated human epidermoid carcinoma A431 cells.
    Akiyama T; Yoshida T; Tsujita T; Shimizu M; Mizukami T; Okabe M; Akinaga S
    Cancer Res; 1997 Apr; 57(8):1495-501. PubMed ID: 9108451
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Molecular mechanisms underlying interferon-alpha-induced G0/G1 arrest: CKI-mediated regulation of G1 Cdk-complexes and activation of pocket proteins.
    Sangfelt O; Erickson S; Castro J; Heiden T; Gustafsson A; Einhorn S; Grandér D
    Oncogene; 1999 May; 18(18):2798-810. PubMed ID: 10362250
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cell cycle exit during terminal erythroid differentiation is associated with accumulation of p27(Kip1) and inactivation of cdk2 kinase.
    Hsieh FF; Barnett LA; Green WF; Freedman K; Matushansky I; Skoultchi AI; Kelley LL
    Blood; 2000 Oct; 96(8):2746-54. PubMed ID: 11023508
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Lovastatin mediated G1 arrest in normal and tumor breast cells is through inhibition of CDK2 activity and redistribution of p21 and p27, independent of p53.
    Rao S; Lowe M; Herliczek TW; Keyomarsi K
    Oncogene; 1998 Nov; 17(18):2393-402. PubMed ID: 9811471
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Flavopiridol induces G1 arrest with inhibition of cyclin-dependent kinase (CDK) 2 and CDK4 in human breast carcinoma cells.
    Carlson BA; Dubay MM; Sausville EA; Brizuela L; Worland PJ
    Cancer Res; 1996 Jul; 56(13):2973-8. PubMed ID: 8674031
    [TBL] [Abstract][Full Text] [Related]  

  • 9. CDK2 is a target for retinoic acid-mediated growth inhibition in MCF-7 human breast cancer cells.
    Teixeira C; Pratt MA
    Mol Endocrinol; 1997 Aug; 11(9):1191-202. PubMed ID: 9259311
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The cancer preventive flavonoid silibinin causes hypophosphorylation of Rb/p107 and Rb2/p130 via modulation of cell cycle regulators in human prostate carcinoma DU145 cells.
    Tyagi A; Agarwal C; Agarwal R
    Cell Cycle; 2002; 1(2):137-42. PubMed ID: 12429923
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta.
    Reynisdóttir I; Polyak K; Iavarone A; Massagué J
    Genes Dev; 1995 Aug; 9(15):1831-45. PubMed ID: 7649471
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Doenjang hexane fraction-induced G1 arrest is associated with the inhibition of pRB phosphorylation and induction of Cdk inhibitor p21 in human breast carcinoma MCF-7 cells.
    Choi YH; Choi BT; Lee WH; Rhee SH; Park KY
    Oncol Rep; 2001; 8(5):1091-6. PubMed ID: 11496322
    [TBL] [Abstract][Full Text] [Related]  

  • 13. BMP-7-induced cell cycle arrest of anaplastic thyroid carcinoma cells via p21(CIP1) and p27(KIP1).
    Franzén A ; Heldin NE
    Biochem Biophys Res Commun; 2001 Jul; 285(3):773-81. PubMed ID: 11453659
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibition of the melanoma cell cycle and regulation at the G1/S transition by 12-O-tetradecanoylphorbol-13-acetate (TPA) by modulation of CDK2 activity.
    Coppock DL; Buffolino P; Kopman C; Nathanson L
    Exp Cell Res; 1995 Nov; 221(1):92-102. PubMed ID: 7589260
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Estrogen-induced activation of Cdk4 and Cdk2 during G1-S phase progression is accompanied by increased cyclin D1 expression and decreased cyclin-dependent kinase inhibitor association with cyclin E-Cdk2.
    Prall OW; Sarcevic B; Musgrove EA; Watts CK; Sutherland RL
    J Biol Chem; 1997 Apr; 272(16):10882-94. PubMed ID: 9099745
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Involvement of p27Kip1 in G1 arrest by high dose 5 alpha-dihydrotestosterone in LNCaP human prostate cancer cells.
    Tsihlias J; Zhang W; Bhattacharya N; Flanagan M; Klotz L; Slingerland J
    Oncogene; 2000 Feb; 19(5):670-9. PubMed ID: 10698512
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Involvement of p21 and p27 in the regulation of CDK activity and cell cycle progression in the regenerating liver.
    Albrecht JH; Poon RY; Ahonen CL; Rieland BM; Deng C; Crary GS
    Oncogene; 1998 Apr; 16(16):2141-50. PubMed ID: 9572495
    [TBL] [Abstract][Full Text] [Related]  

  • 18. CaMK-II inhibition reduces cyclin D1 levels and enhances the association of p27kip1 with Cdk2 to cause G1 arrest in NIH 3T3 cells.
    Morris TA; DeLorenzo RJ; Tombes RM
    Exp Cell Res; 1998 May; 240(2):218-27. PubMed ID: 9596994
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Lactoferrin inhibits G1 cyclin-dependent kinases during growth arrest of human breast carcinoma cells.
    Damiens E; El Yazidi I; Mazurier J; Duthille I; Spik G; Boilly-Marer Y
    J Cell Biochem; 1999 Sep; 74(3):486-98. PubMed ID: 10412049
    [TBL] [Abstract][Full Text] [Related]  

  • 20. G1-checkpoint function including a cyclin-dependent kinase 2 regulatory pathway as potential determinant of 7-hydroxystaurosporine (UCN-01)-induced apoptosis and G1-phase accumulation.
    Akiyama T; Sugiyama K; Shimizu M; Tamaoki T; Akinaga S
    Jpn J Cancer Res; 1999 Dec; 90(12):1364-72. PubMed ID: 10665655
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 35.