BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

160 related articles for article (PubMed ID: 12376486)

  • 1. Mutations induced by alpha-hydroxytamoxifen in the lacI and cII genes of Big Blue transgenic rats.
    Chen T; Gamboa da Costa G; Marques MM; Shelton SD; Beland FA; Manjanatha MG
    Carcinogenesis; 2002 Oct; 23(10):1751-7. PubMed ID: 12376486
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Induction of lacI mutations in Big Blue rats treated with tamoxifen and alpha-hydroxytamoxifen.
    Gamboa da Costa G; Manjanatha MG; Marques MM; Beland FA
    Cancer Lett; 2002 Feb; 176(1):37-45. PubMed ID: 11790452
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Spontaneous and ENU-induced mutation spectra at the cII locus in Big Blue Rat2 embryonic fibroblasts.
    Watson DE; Cunningham ML; Tindall KR
    Mutagenesis; 1998 Sep; 13(5):487-97. PubMed ID: 9800194
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Tamoxifen induces G:C-->T:A mutations in the cII gene in the liver of lambda/lacI transgenic rats but not at 5'-CpG-3' dinucleotide sequences as found in the lacI transgene.
    Davies R; Gant TW; Smith LL; Styles JA
    Carcinogenesis; 1999 Jul; 20(7):1351-6. PubMed ID: 10383911
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mutant frequencies and mutation spectra of dimethylnitrosamine (DMN) at the lacI and cII loci in the livers of Big Blue transgenic mice.
    Shane BS; Smith-Dunn DL; de Boer JG; Glickman BW; Cunningham ML
    Mutat Res; 2000 Sep; 452(2):197-210. PubMed ID: 11024479
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mutational spectra of tamoxifen-induced mutations in the livers of lacI transgenic rats.
    Davies R; Oreffo VI; Bayliss S; Dinh PA; Lilley KS; White IN; Smith LL; Styles JA
    Environ Mol Mutagen; 1996; 28(4):430-3. PubMed ID: 8991074
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Comparison of mutant frequencies and types of mutations induced by thiotepa in the endogenous Hprt gene and transgenic lacI gene of Big Blue rats.
    Chen T; Aidoo A; Manjanatha MG; Mittelstaedt RA; Shelton SD; Lyn-Cook LE; Casciano DA; Heflich RH
    Mutat Res; 1998 Jul; 403(1-2):199-214. PubMed ID: 9726020
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Gene- and tissue-specificity of mutation in Big Blue rats treated with the hepatocarcinogen N-hydroxy-2-acetylaminofluorene.
    Chen T; Mittelstaedt RA; Shelton SD; Dass SB; Manjanatha MG; Casciano DA; Heflich RH
    Environ Mol Mutagen; 2001; 37(3):203-14. PubMed ID: 11317338
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Comparison of mutant frequencies at the transgenic lambda LacI and cII/cI loci in control and ENU-treated Big Blue mice.
    Zimmer DM; Harbach PR; Mattes WB; Aaron CS
    Environ Mol Mutagen; 1999; 33(3):249-56. PubMed ID: 10334627
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mutation spectrum of 4-nitroquinoline N-oxide in the lacI transgenic Big Blue Rat2 cell line.
    Ryu J; Youn J; Kim Y; Kwon O; Song Y; Kim H; Cho K; Chang I
    Mutat Res; 1999 Sep; 445(1):127-35. PubMed ID: 10521698
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Comparison of hprt and lacI mutant frequency with DNA adduct formation in N-hydroxy-2-acetylaminofluorene-treated Big Blue rats.
    Chen T; Mittelstaedt RA; Aidoo A; Hamilton LP; Beland FA; Casciano DA; Heflich RH
    Environ Mol Mutagen; 2001; 37(3):195-202. PubMed ID: 11317337
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Interpretation of mutational spectra from different genes: analyses of PhIP-induced mutational specificity in the lacI and cII transgenes from colon of Big Blue rats.
    Stuart GR; Thorleifson E; Okochi E; de Boer JG; Ushijima T; Nagao M; Glickman BW
    Mutat Res; 2000 Jul; 452(1):101-21. PubMed ID: 10894896
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Detection of tamoxifen-DNA adducts on lacI genes using DNA polymerase stop assay.
    Cheng RH; Gant TW
    Changgeng Yi Xue Za Zhi; 1999 Jun; 22(2):189-96. PubMed ID: 10493022
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A comparative study of in vivo mutation assays: analysis of hprt, lacI, cII/cI and as mutational targets for N-nitroso-N-methylurea and benzo[a]pyrene in Big Blue mice.
    Monroe JJ; Kort KL; Miller JE; Marino DR; Skopek TR
    Mutat Res; 1998 Oct; 421(1):121-36. PubMed ID: 9748534
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The mutational signature of alpha-hydroxytamoxifen at Hprt locus in Chinese hamster cells.
    Yadollahi-Farsani M; Davies DS; Boobis AR
    Carcinogenesis; 2002 Nov; 23(11):1947-52. PubMed ID: 12419845
    [TBL] [Abstract][Full Text] [Related]  

  • 16. DNA adduct formation and mutant induction in Sprague-Dawley rats treated with tamoxifen and its derivatives.
    Gamboa da Costa G; McDaniel-Hamilton LP; Heflich RH; Marques MM; Beland FA
    Carcinogenesis; 2001 Aug; 22(8):1307-15. PubMed ID: 11470763
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 1,3-butadiene: cancer, mutations, and adducts. Part II: Roles of two metabolites of 1,3-butadiene in mediating its in vivo genotoxicity.
    Recio L; Saranko CJ; Steen AM
    Res Rep Health Eff Inst; 2000 Mar; (92):49-87; discussion 141-9. PubMed ID: 10925839
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The genetic analysis of lacI mutations in sectored plaques from Big Blue transgenic mice.
    Stuart GR; Gorelick NJ; Andrews JL; de Boer JG; Glickman BW
    Environ Mol Mutagen; 1996; 28(4):385-92. PubMed ID: 8991067
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mutational analysis of the liver, colon and kidney of Big Blue rats treated with 2-amino-3-methylimidazo[4,5-f]quinoline.
    Bol SA; Horlbeck J; Markovic J; de Boer JG; Turesky RJ; Constable A
    Carcinogenesis; 2000 Jan; 21(1):1-6. PubMed ID: 10607726
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Spontaneous mutation spectrum at the lambda cII locus in liver, lung, and spleen tissue of Big Blue transgenic mice.
    Harbach PR; Zimmer DM; Filipunas AL; Mattes WB; Aaron CS
    Environ Mol Mutagen; 1999; 33(2):132-43. PubMed ID: 10217067
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.