BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

149 related articles for article (PubMed ID: 12376540)

  • 1. LL5beta is a phosphatidylinositol (3,4,5)-trisphosphate sensor that can bind the cytoskeletal adaptor, gamma-filamin.
    Paranavitane V; Coadwell WJ; Eguinoa A; Hawkins PT; Stephens L
    J Biol Chem; 2003 Jan; 278(2):1328-35. PubMed ID: 12376540
    [TBL] [Abstract][Full Text] [Related]  

  • 2. LL5beta directs the translocation of filamin A and SHIP2 to sites of phosphatidylinositol 3,4,5-triphosphate (PtdIns(3,4,5)P3) accumulation, and PtdIns(3,4,5)P3 localization is mutually modified by co-recruited SHIP2.
    Takabayashi T; Xie MJ; Takeuchi S; Kawasaki M; Yagi H; Okamoto M; Tariqur RM; Malik F; Kuroda K; Kubota C; Fujieda S; Nagano T; Sato M
    J Biol Chem; 2010 May; 285(21):16155-65. PubMed ID: 20236936
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structural determinants of LL5beta subcellular localisation and association with filamin C.
    Paranavitane V; Stephens LR; Hawkins PT
    Cell Signal; 2007 Apr; 19(4):817-24. PubMed ID: 17174070
    [TBL] [Abstract][Full Text] [Related]  

  • 4. SHIP-2 forms a tetrameric complex with filamin, actin, and GPIb-IX-V: localization of SHIP-2 to the activated platelet actin cytoskeleton.
    Dyson JM; Munday AD; Kong AM; Huysmans RD; Matzaris M; Layton MJ; Nandurkar HH; Berndt MC; Mitchell CA
    Blood; 2003 Aug; 102(3):940-8. PubMed ID: 12676785
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A target of phosphatidylinositol 3,4,5-trisphosphate with a zinc finger motif similar to that of the ADP-ribosylation-factor GTPase-activating protein and two pleckstrin homology domains.
    Tanaka K; Imajoh-Ohmi S; Sawada T; Shirai R; Hashimoto Y; Iwasaki S; Kaibuchi K; Kanaho Y; Shirai T; Terada Y; Kimura K; Nagata S; Fukui Y
    Eur J Biochem; 1997 Apr; 245(2):512-9. PubMed ID: 9151987
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification of centaurin-alpha1 as a potential in vivo phosphatidylinositol 3,4,5-trisphosphate-binding protein that is functionally homologous to the yeast ADP-ribosylation factor (ARF) GTPase-activating protein, Gcs1.
    Venkateswarlu K; Oatey PB; Tavaré JM; Jackson TR; Cullen PJ
    Biochem J; 1999 Jun; 340 ( Pt 2)(Pt 2):359-63. PubMed ID: 10333475
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Evidence that the tandem-pleckstrin-homology-domain-containing protein TAPP1 interacts with Ptd(3,4)P2 and the multi-PDZ-domain-containing protein MUPP1 in vivo.
    Kimber WA; Trinkle-Mulcahy L; Cheung PC; Deak M; Marsden LJ; Kieloch A; Watt S; Javier RT; Gray A; Downes CP; Lucocq JM; Alessi DR
    Biochem J; 2002 Feb; 361(Pt 3):525-36. PubMed ID: 11802782
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Expression cloning of protein targets for 3-phosphorylated phosphoinositides.
    Rao VR; Corradetti MN; Chen J; Peng J; Yuan J; Prestwich GD; Brugge JS
    J Biol Chem; 1999 Dec; 274(53):37893-900. PubMed ID: 10608855
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Crystal structure of the phosphatidylinositol 3,4-bisphosphate-binding pleckstrin homology (PH) domain of tandem PH-domain-containing protein 1 (TAPP1): molecular basis of lipid specificity.
    Thomas CC; Dowler S; Deak M; Alessi DR; van Aalten DM
    Biochem J; 2001 Sep; 358(Pt 2):287-94. PubMed ID: 11513726
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Phox homology domains specifically bind phosphatidylinositol phosphates.
    Song X; Xu W; Zhang A; Huang G; Liang X; Virbasius JV; Czech MP; Zhou GW
    Biochemistry; 2001 Jul; 40(30):8940-4. PubMed ID: 11467955
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Nerve growth factor- and epidermal growth factor-stimulated translocation of the ADP-ribosylation factor-exchange factor GRP1 to the plasma membrane of PC12 cells requires activation of phosphatidylinositol 3-kinase and the GRP1 pleckstrin homology domain.
    Venkateswarlu K; Gunn-Moore F; Oatey PB; Tavaré JM; Cullen PJ
    Biochem J; 1998 Oct; 335 ( Pt 1)(Pt 1):139-46. PubMed ID: 9742223
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Targeting of Golgi-specific pleckstrin homology domains involves both PtdIns 4-kinase-dependent and -independent components.
    Levine TP; Munro S
    Curr Biol; 2002 Apr; 12(9):695-704. PubMed ID: 12007412
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The SH2-containing inositol polyphosphate 5-phosphatase, SHIP-2, binds filamin and regulates submembraneous actin.
    Dyson JM; O'Malley CJ; Becanovic J; Munday AD; Berndt MC; Coghill ID; Nandurkar HH; Ooms LM; Mitchell CA
    J Cell Biol; 2001 Dec; 155(6):1065-79. PubMed ID: 11739414
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification and analysis of PH domain-containing targets of phosphatidylinositol 3-kinase using a novel in vivo assay in yeast.
    Isakoff SJ; Cardozo T; Andreev J; Li Z; Ferguson KM; Abagyan R; Lemmon MA; Aronheim A; Skolnik EY
    EMBO J; 1998 Sep; 17(18):5374-87. PubMed ID: 9736615
    [TBL] [Abstract][Full Text] [Related]  

  • 15. BMP2-induced chemotaxis requires PI3K p55γ/p110α-dependent phosphatidylinositol (3,4,5)-triphosphate production and LL5β recruitment at the cytocortex.
    Hiepen C; Benn A; Denkis A; Lukonin I; Weise C; Boergermann JH; Knaus P
    BMC Biol; 2014 May; 12():43. PubMed ID: 24885555
    [TBL] [Abstract][Full Text] [Related]  

  • 16. High-resolution structure of the pleckstrin homology domain of protein kinase b/akt bound to phosphatidylinositol (3,4,5)-trisphosphate.
    Thomas CC; Deak M; Alessi DR; van Aalten DM
    Curr Biol; 2002 Jul; 12(14):1256-62. PubMed ID: 12176338
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Ceramide dissociates 3'-phosphoinositide production from pleckstrin homology domain translocation.
    Stratford S; DeWald DB; Summers SA
    Biochem J; 2001 Mar; 354(Pt 2):359-68. PubMed ID: 11171115
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities.
    Dowler S; Currie RA; Campbell DG; Deak M; Kular G; Downes CP; Alessi DR
    Biochem J; 2000 Oct; 351(Pt 1):19-31. PubMed ID: 11001876
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A comparative analysis of the phosphoinositide binding specificity of pleckstrin homology domains.
    Rameh LE; Arvidsson Ak; Carraway KL; Couvillon AD; Rathbun G; Crompton A; VanRenterghem B; Czech MP; Ravichandran KS; Burakoff SJ; Wang DS; Chen CS; Cantley LC
    J Biol Chem; 1997 Aug; 272(35):22059-66. PubMed ID: 9268346
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Lipid products of phosphoinositide 3-kinase bind human profilin with high affinity.
    Lu PJ; Shieh WR; Rhee SG; Yin HL; Chen CS
    Biochemistry; 1996 Nov; 35(44):14027-34. PubMed ID: 8909300
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.