181 related articles for article (PubMed ID: 12379118)
1. SCH28080, a K+-competitive inhibitor of the gastric H,K-ATPase, binds near the M5-6 luminal loop, preventing K+ access to the ion binding domain.
Vagin O; Denevich S; Munson K; Sachs G
Biochemistry; 2002 Oct; 41(42):12755-62. PubMed ID: 12379118
[TBL] [Abstract][Full Text] [Related]
2. Mutational analysis of the K+-competitive inhibitor site of gastric H,K-ATPase.
Vagin O; Munson K; Lambrecht N; Karlish SJ; Sachs G
Biochemistry; 2001 Jun; 40(25):7480-90. PubMed ID: 11412101
[TBL] [Abstract][Full Text] [Related]
3. Inhibition kinetics of the gastric H,K-ATPase by K-competitive inhibitor SCH28080 as a tool for investigating the luminal ion pathway.
Vagin O; Munson K; Denevich S; Sachs G
Ann N Y Acad Sci; 2003 Apr; 986():111-5. PubMed ID: 12763783
[TBL] [Abstract][Full Text] [Related]
4. Effects of mutations in M4 of the gastric H+,K+-ATPase on inhibition kinetics of SCH28080.
Munson KB; Lambrecht N; Sachs G
Biochemistry; 2000 Mar; 39(11):2997-3004. PubMed ID: 10715120
[TBL] [Abstract][Full Text] [Related]
5. Analysis of the gastric H,K ATPase for ion pathways and inhibitor binding sites.
Munson K; Law RJ; Sachs G
Biochemistry; 2007 May; 46(18):5398-417. PubMed ID: 17425287
[TBL] [Abstract][Full Text] [Related]
6. Comparison of covalent with reversible inhibitor binding sites of the gastric H,K-ATPase by site-directed mutagenesis.
Lambrecht N; Munson K; Vagin O; Sachs G
J Biol Chem; 2000 Feb; 275(6):4041-8. PubMed ID: 10660561
[TBL] [Abstract][Full Text] [Related]
7. Chemomechanical coupling in the gastric H,K ATPase.
Besancon M; Shin JM; Mercier F; Munson K; Rabon E; Hersey S; Sachs G
Acta Physiol Scand Suppl; 1992; 607():77-88. PubMed ID: 1333163
[TBL] [Abstract][Full Text] [Related]
8. Structural aspects of the gastric H,K-ATPase.
Sachs G; Besancon M; Shin JM; Mercier F; Munson K; Hersey S
J Bioenerg Biomembr; 1992 Jun; 24(3):301-8. PubMed ID: 1383197
[TBL] [Abstract][Full Text] [Related]
9. Molecular modeling of SCH28080 binding to the gastric H,K-ATPase and MgATP interactions with SERCA- and Na,K-ATPases.
Munson K; Vagin O; Sachs G; Karlish S
Ann N Y Acad Sci; 2003 Apr; 986():106-10. PubMed ID: 12763782
[TBL] [Abstract][Full Text] [Related]
10. The gastric H,K ATPase as a drug target: past, present, and future.
Sachs G; Shin JM; Vagin O; Lambrecht N; Yakubov I; Munson K
J Clin Gastroenterol; 2007 Jul; 41 Suppl 2(Suppl 2):S226-42. PubMed ID: 17575528
[TBL] [Abstract][Full Text] [Related]
11. The negative charge of glutamic acid-820 in the gastric H+,K+-ATPase alpha-subunit is essential for K+ activation of the enzyme activity.
Hermsen HP; Swarts HG; Koenderink JB; De Pont JJ
Biochem J; 1998 Apr; 331 ( Pt 2)(Pt 2):465-72. PubMed ID: 9531486
[TBL] [Abstract][Full Text] [Related]
12. A model of reversible inhibitors in the gastric H+/K+-ATPase binding site determined by rotational echo double resonance NMR.
Watts JA; Watts A; Middleton DA
J Biol Chem; 2001 Nov; 276(46):43197-204. PubMed ID: 11479301
[TBL] [Abstract][Full Text] [Related]
13. Point mutations in the extracytosolic loop between transmembrane segments M5 and M6 of the yeast Pma1 H+-ATPase: alanine-scanning mutagenesis.
Petrov VV
J Biomol Struct Dyn; 2015; 33(1):70-84. PubMed ID: 24256122
[TBL] [Abstract][Full Text] [Related]
14. Mutational analysis of putative SCH 28080 binding sites of the gastric H+,K+-ATPase.
Asano S; Matsuda S; Tega Y; Shimizu K; Sakamoto S; Takeguchi N
J Biol Chem; 1997 Jul; 272(28):17668-74. PubMed ID: 9211917
[TBL] [Abstract][Full Text] [Related]
15. Cibenzoline, an ATP-sensitive K(+) channel blocker, binds to the K(+)-binding site from the cytoplasmic side of gastric H(+),K(+)-ATPase.
Tabuchi Y; Yashiro H; Hoshina S; Asano S; Takeguchi N
Br J Pharmacol; 2001 Dec; 134(8):1655-62. PubMed ID: 11739241
[TBL] [Abstract][Full Text] [Related]
16. Studies on the mechanism of action of the gastric H+,K(+)-ATPase inhibitor SPI-447.
Tsukimi Y; Ushiro T; Yamazaki T; Ishikawa H; Hirase J; Narita M; Nishigaito T; Banno K; Ichihara T; Tanaka H
Jpn J Pharmacol; 2000 Jan; 82(1):21-8. PubMed ID: 10874584
[TBL] [Abstract][Full Text] [Related]
17. Identification of the site of inhibition by omeprazole of a alpha-beta fusion protein of the H,K-ATPase using site-directed mutagenesis.
Lambrecht N; Corbett Z; Bayle D; Karlish SJ; Sachs G
J Biol Chem; 1998 May; 273(22):13719-28. PubMed ID: 9593713
[TBL] [Abstract][Full Text] [Related]
18. A chimeric gastric H+,K+-ATPase inhibitable with both ouabain and SCH 28080.
Asano S; Matsuda S; Hoshina S; Sakamoto S; Takeguchi N
J Biol Chem; 1999 Mar; 274(11):6848-54. PubMed ID: 10066737
[TBL] [Abstract][Full Text] [Related]
19. Inhibitor and ion binding sites on the gastric H,K-ATPase.
Munson K; Garcia R; Sachs G
Biochemistry; 2005 Apr; 44(14):5267-84. PubMed ID: 15807521
[TBL] [Abstract][Full Text] [Related]
20. Arginine substitution of a cysteine in transmembrane helix M8 converts Na+,K+-ATPase to an electroneutral pump similar to H+,K+-ATPase.
Holm R; Khandelwal J; Einholm AP; Andersen JP; Artigas P; Vilsen B
Proc Natl Acad Sci U S A; 2017 Jan; 114(2):316-321. PubMed ID: 28028214
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
