309 related articles for article (PubMed ID: 12384432)
1. In the presence of bone marrow stromal cells human multiple myeloma cells become independent of the IL-6/gp130/STAT3 pathway.
Chatterjee M; Hönemann D; Lentzsch S; Bommert K; Sers C; Herrmann P; Mathas S; Dörken B; Bargou RC
Blood; 2002 Nov; 100(9):3311-8. PubMed ID: 12384432
[TBL] [Abstract][Full Text] [Related]
2. Interleukin-6, CD45 and the src-kinases in myeloma cell proliferation.
Ishikawa H; Tsuyama N; Abroun S; Liu S; Li FJ; Otsuyama K; Zheng X; Kawano MM
Leuk Lymphoma; 2003 Sep; 44(9):1477-81. PubMed ID: 14565647
[TBL] [Abstract][Full Text] [Related]
3. Combined disruption of both the MEK/ERK and the IL-6R/STAT3 pathways is required to induce apoptosis of multiple myeloma cells in the presence of bone marrow stromal cells.
Chatterjee M; Stühmer T; Herrmann P; Bommert K; Dörken B; Bargou RC
Blood; 2004 Dec; 104(12):3712-21. PubMed ID: 15297310
[TBL] [Abstract][Full Text] [Related]
4. Downstream effectors of oncogenic ras in multiple myeloma cells.
Hu L; Shi Y; Hsu JH; Gera J; Van Ness B; Lichtenstein A
Blood; 2003 Apr; 101(8):3126-35. PubMed ID: 12515720
[TBL] [Abstract][Full Text] [Related]
5. Dual signaling role of the protein tyrosine phosphatase SHP-2 in regulating expression of acute-phase plasma proteins by interleukin-6 cytokine receptors in hepatic cells.
Kim H; Baumann H
Mol Cell Biol; 1999 Aug; 19(8):5326-38. PubMed ID: 10409724
[TBL] [Abstract][Full Text] [Related]
6. Thrombopoietin, but not cytokines binding to gp130 protein-coupled receptors, activates MAPKp42/44, AKT, and STAT proteins in normal human CD34+ cells, megakaryocytes, and platelets.
Majka M; Ratajczak J; Villaire G; Kubiczek K; Marquez LA; Janowska-Wieczorek A; Ratajczak MZ
Exp Hematol; 2002 Jul; 30(7):751-60. PubMed ID: 12135673
[TBL] [Abstract][Full Text] [Related]
7. JAK2 tyrosine kinase inhibitor tyrphostin AG490 downregulates the mitogen-activated protein kinase (MAPK) and signal transducer and activator of transcription (STAT) pathways and induces apoptosis in myeloma cells.
De Vos J; Jourdan M; Tarte K; Jasmin C; Klein B
Br J Haematol; 2000 Jun; 109(4):823-8. PubMed ID: 10929036
[TBL] [Abstract][Full Text] [Related]
8. IL-6 triggers cell growth via the Ras-dependent mitogen-activated protein kinase cascade.
Ogata A; Chauhan D; Teoh G; Treon SP; Urashima M; Schlossman RL; Anderson KC
J Immunol; 1997 Sep; 159(5):2212-21. PubMed ID: 9278309
[TBL] [Abstract][Full Text] [Related]
9. Gp130 and ras mediated signaling in human plasma cell line INA-6: a cytokine-regulated tumor model for plasmacytoma.
Burger R; Guenther A; Bakker F; Schmalzing M; Bernand S; Baum W; Duerr B; Hocke GM; Steininger H; Gebhart E; Gramatzki M
Hematol J; 2001; 2(1):42-53. PubMed ID: 11920233
[TBL] [Abstract][Full Text] [Related]
10. Farnesyl transferase inhibitor R115777 induces apoptosis of human myeloma cells.
Le Gouill S; Pellat-Deceunynck C; Harousseau JL; Rapp MJ; Robillard N; Bataille R; Amiot M
Leukemia; 2002 Sep; 16(9):1664-7. PubMed ID: 12200678
[TBL] [Abstract][Full Text] [Related]
11. Signaling pathway of ciliary neurotrophic factor in neuroblastoma cell lines.
Kuroda H; Sugimoto T; Horii Y; Sawada T
Med Pediatr Oncol; 2001 Jan; 36(1):118-21. PubMed ID: 11464862
[TBL] [Abstract][Full Text] [Related]
12. STAT3, but not ERKs, mediates the IL-6-induced proliferation of renal cancer cells, ACHN and 769P.
Horiguchi A; Oya M; Marumo K; Murai M
Kidney Int; 2002 Mar; 61(3):926-38. PubMed ID: 11849447
[TBL] [Abstract][Full Text] [Related]
13. Functional significance of novel neurotrophin-1/B cell-stimulating factor-3 (cardiotrophin-like cytokine) for human myeloma cell growth and survival.
Burger R; Bakker F; Guenther A; Baum W; Schmidt-Arras D; Hideshima T; Tai YT; Shringarpure R; Catley L; Senaldi G; Gramatzki M; Anderson KC
Br J Haematol; 2003 Dec; 123(5):869-78. PubMed ID: 14632778
[TBL] [Abstract][Full Text] [Related]
14. The protein tyrosine phosphatase CD45 is required for interleukin 6 signaling in U266 myeloma cells.
Zhou Q; Yao Y; Ericson SG
Int J Hematol; 2004 Jan; 79(1):63-73. PubMed ID: 14979481
[TBL] [Abstract][Full Text] [Related]
15. Activation of the protein tyrosine phosphatase SHP2 via the interleukin-6 signal transducing receptor protein gp130 requires tyrosine kinase Jak1 and limits acute-phase protein expression.
Schaper F; Gendo C; Eck M; Schmitz J; Grimm C; Anhuf D; Kerr IM; Heinrich PC
Biochem J; 1998 Nov; 335 ( Pt 3)(Pt 3):557-65. PubMed ID: 9794795
[TBL] [Abstract][Full Text] [Related]
16. Epidermal growth factor receptor-independent constitutive activation of STAT3 in head and neck squamous cell carcinoma is mediated by the autocrine/paracrine stimulation of the interleukin 6/gp130 cytokine system.
Sriuranpong V; Park JI; Amornphimoltham P; Patel V; Nelkin BD; Gutkind JS
Cancer Res; 2003 Jun; 63(11):2948-56. PubMed ID: 12782602
[TBL] [Abstract][Full Text] [Related]
17. TNF-alpha induces tyrosine phosphorylation and recruitment of the Src homology protein-tyrosine phosphatase 2 to the gp130 signal-transducing subunit of the IL-6 receptor complex.
Bode JG; Schweigart J; Kehrmann J; Ehlting C; Schaper F; Heinrich PC; Häussinger D
J Immunol; 2003 Jul; 171(1):257-66. PubMed ID: 12817006
[TBL] [Abstract][Full Text] [Related]
18. Pyridone 6, a pan-Janus-activated kinase inhibitor, induces growth inhibition of multiple myeloma cells.
Pedranzini L; Dechow T; Berishaj M; Comenzo R; Zhou P; Azare J; Bornmann W; Bromberg J
Cancer Res; 2006 Oct; 66(19):9714-21. PubMed ID: 17018630
[TBL] [Abstract][Full Text] [Related]
19. Characterization of signaling cascades triggered by human interleukin-6 versus Kaposi's sarcoma-associated herpes virus-encoded viral interleukin 6.
Hideshima T; Chauhan D; Teoh G; Raje N; Treon SP; Tai YT; Shima Y; Anderson KC
Clin Cancer Res; 2000 Mar; 6(3):1180-9. PubMed ID: 10741750
[TBL] [Abstract][Full Text] [Related]
20. Activation of JAK-STAT and MAP kinases by leukemia inhibitory factor through gp130 in cardiac myocytes.
Kunisada K; Hirota H; Fujio Y; Matsui H; Tani Y; Yamauchi-Takihara K; Kishimoto T
Circulation; 1996 Nov; 94(10):2626-32. PubMed ID: 8921810
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]