297 related articles for article (PubMed ID: 12386337)
1. Neurotoxicity and neurodegeneration when PrP accumulates in the cytosol.
Ma J; Wollmann R; Lindquist S
Science; 2002 Nov; 298(5599):1781-5. PubMed ID: 12386337
[TBL] [Abstract][Full Text] [Related]
2. Conversion of PrP to a self-perpetuating PrPSc-like conformation in the cytosol.
Ma J; Lindquist S
Science; 2002 Nov; 298(5599):1785-8. PubMed ID: 12386336
[TBL] [Abstract][Full Text] [Related]
3. Cytosolic prion protein toxicity is independent of cellular prion protein expression and prion propagation.
Norstrom EM; Ciaccio MF; Rassbach B; Wollmann R; Mastrianni JA
J Virol; 2007 Mar; 81(6):2831-7. PubMed ID: 17182694
[TBL] [Abstract][Full Text] [Related]
4. Cytosolic prion protein (PrP) is not toxic in N2a cells and primary neurons expressing pathogenic PrP mutations.
Fioriti L; Dossena S; Stewart LR; Stewart RS; Harris DA; Forloni G; Chiesa R
J Biol Chem; 2005 Mar; 280(12):11320-8. PubMed ID: 15632159
[TBL] [Abstract][Full Text] [Related]
5. Molecular mechanisms of neurotoxicity of pathological prion protein.
Castilla J; Hetz C; Soto C
Curr Mol Med; 2004 Jun; 4(4):397-403. PubMed ID: 15354870
[TBL] [Abstract][Full Text] [Related]
6. Sc237 hamster PrPSc and Sc237-derived mouse PrPSc generated by interspecies in vitro amplification exhibit distinct pathological and biochemical properties in tga20 transgenic mice.
Yoshioka M; Imamura M; Okada H; Shimozaki N; Murayama Y; Yokoyama T; Mohri S
Microbiol Immunol; 2011 May; 55(5):331-40. PubMed ID: 21362027
[TBL] [Abstract][Full Text] [Related]
7. Wild-type PrP and a mutant associated with prion disease are subject to retrograde transport and proteasome degradation.
Ma J; Lindquist S
Proc Natl Acad Sci U S A; 2001 Dec; 98(26):14955-60. PubMed ID: 11742063
[TBL] [Abstract][Full Text] [Related]
8. Prion proteins meet protein quality control.
Dimcheff DE; Portis JL; Caughey B
Trends Cell Biol; 2003 Jul; 13(7):337-40. PubMed ID: 12837603
[TBL] [Abstract][Full Text] [Related]
9. Aggresome formation by mutant prion proteins: the unfolding role of proteasomes in familial prion disorders.
Mishra RS; Bose S; Gu Y; Li R; Singh N
J Alzheimers Dis; 2003 Feb; 5(1):15-23. PubMed ID: 12590162
[TBL] [Abstract][Full Text] [Related]
10. Prion diseases: what is the neurotoxic molecule?
Chiesa R; Harris DA
Neurobiol Dis; 2001 Oct; 8(5):743-63. PubMed ID: 11592845
[TBL] [Abstract][Full Text] [Related]
11. A transmembrane form of the prion protein in neurodegenerative disease.
Hegde RS; Mastrianni JA; Scott MR; DeFea KA; Tremblay P; Torchia M; DeArmond SJ; Prusiner SB; Lingappa VR
Science; 1998 Feb; 279(5352):827-34. PubMed ID: 9452375
[TBL] [Abstract][Full Text] [Related]
12. Prions can infect primary cultured neurons and astrocytes and promote neuronal cell death.
Cronier S; Laude H; Peyrin JM
Proc Natl Acad Sci U S A; 2004 Aug; 101(33):12271-6. PubMed ID: 15302929
[TBL] [Abstract][Full Text] [Related]
13. Transmissible and genetic prion diseases share a common pathway of neurodegeneration.
Hegde RS; Tremblay P; Groth D; DeArmond SJ; Prusiner SB; Lingappa VR
Nature; 1999 Dec; 402(6763):822-6. PubMed ID: 10617204
[TBL] [Abstract][Full Text] [Related]
14. Calpain and other cytosolic proteases can contribute to the degradation of retro-translocated prion protein in the cytosol.
Wang X; Wang F; Sy MS; Ma J
J Biol Chem; 2005 Jan; 280(1):317-25. PubMed ID: 15525638
[TBL] [Abstract][Full Text] [Related]
15. Proteasomes and ubiquitin are involved in the turnover of the wild-type prion protein.
Yedidia Y; Horonchik L; Tzaban S; Yanai A; Taraboulos A
EMBO J; 2001 Oct; 20(19):5383-91. PubMed ID: 11574470
[TBL] [Abstract][Full Text] [Related]
16. Cytosolic prion protein is not toxic and protects against Bax-mediated cell death in human primary neurons.
Roucou X; Guo Q; Zhang Y; Goodyer CG; LeBlanc AC
J Biol Chem; 2003 Oct; 278(42):40877-81. PubMed ID: 12917444
[TBL] [Abstract][Full Text] [Related]
17. Prion Infectivity Plateaus and Conversion to Symptomatic Disease Originate from Falling Precursor Levels and Increased Levels of Oligomeric PrPSc Species.
Mays CE; van der Merwe J; Kim C; Haldiman T; McKenzie D; Safar JG; Westaway D
J Virol; 2015 Dec; 89(24):12418-26. PubMed ID: 26423957
[TBL] [Abstract][Full Text] [Related]
18. Disease-related prion protein forms aggresomes in neuronal cells leading to caspase activation and apoptosis.
Kristiansen M; Messenger MJ; Klöhn PC; Brandner S; Wadsworth JD; Collinge J; Tabrizi SJ
J Biol Chem; 2005 Nov; 280(46):38851-61. PubMed ID: 16157591
[TBL] [Abstract][Full Text] [Related]
19. A transgenic model of a familial prion disease.
Harris DA; Chiesa R; Drisaldi B; Quaglio E; Migheli A; Piccardo P; Ghetti B
Arch Virol Suppl; 2000; (16):103-12. PubMed ID: 11214912
[TBL] [Abstract][Full Text] [Related]
20. Polo-like kinase 3 (PLK3) mediates the clearance of the accumulated PrP mutants transiently expressed in cultured cells and pathogenic PrP(Sc) in prion infected cell line via protein interaction.
Wang H; Tian C; Fan XY; Chen LN; Lv Y; Sun J; Zhao YJ; Zhang LB; Wang J; Shi Q; Gao C; Chen C; Shao QX; Dong XP
Int J Biochem Cell Biol; 2015 May; 62():24-35. PubMed ID: 25724737
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
