BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

106 related articles for article (PubMed ID: 12387860)

  • 1. Specificity of substrate recognition by type II dehydroquinases as revealed by binding of polyanions.
    Evans LD; Roszak AW; Noble LJ; Robinson DA; Chalk PA; Matthews JL; Coggins JR; Price NC; Lapthorn AJ
    FEBS Lett; 2002 Oct; 530(1-3):24-30. PubMed ID: 12387860
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The folding and assembly of the dodecameric type II dehydroquinases.
    Price NC; Boam DJ; Kelly SM; Duncan D; Krell T; Gourley DG; Coggins JR; Virden R; Hawkins AR
    Biochem J; 1999 Feb; 338 ( Pt 1)(Pt 1):195-202. PubMed ID: 9931316
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design, synthesis, and structural studies on potent biaryl inhibitors of type II dehydroquinases.
    Payne RJ; Riboldi-Tunnicliffe A; Kerbarh O; Abell AD; Lapthorn AJ; Abell C
    ChemMedChem; 2007 Jul; 2(7):1010-3. PubMed ID: 17487901
    [No Abstract]   [Full Text] [Related]  

  • 4. Mechanistic studies on type I and type II dehydroquinase with (6R)- and (6S)-6-fluoro-3-dehydroquinic acids.
    Parker EJ; González Bello C; Coggins JR; Hawkins AR; Abell C
    Bioorg Med Chem Lett; 2000 Feb; 10(3):231-4. PubMed ID: 10698442
    [TBL] [Abstract][Full Text] [Related]  

  • 5. (1R,4S,5R)-3-Fluoro-1,4,5-trihydroxy-2-cyclohexene-1-carboxylic acid: the fluoro analogue of the enolate intermediate in the reaction catalyzed by type II dehydroquinases.
    Frederickson M; Roszak AW; Coggins JR; Lapthorn AJ; Abell C
    Org Biomol Chem; 2004 Jun; 2(11):1592-6. PubMed ID: 15162210
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structures of native, substrate-bound and inhibited forms of Mycobacterium tuberculosis imidazoleglycerol-phosphate dehydratase.
    Ahangar MS; Vyas R; Nasir N; Biswal BK
    Acta Crystallogr D Biol Crystallogr; 2013 Dec; 69(Pt 12):2461-7. PubMed ID: 24311587
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The structure and mechanism of the type II dehydroquinase from Streptomyces coelicolor.
    Roszak AW; Robinson DA; Krell T; Hunter IS; Fredrickson M; Abell C; Coggins JR; Lapthorn AJ
    Structure; 2002 Apr; 10(4):493-503. PubMed ID: 11937054
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Understanding the key factors that control the inhibition of type II dehydroquinase by (2R)-2-benzyl-3-dehydroquinic acids.
    Peón A; Otero JM; Tizón L; Prazeres VF; Llamas-Saiz AL; Fox GC; van Raaij MJ; Lamb H; Hawkins AR; Gago F; Castedo L; González-Bello C
    ChemMedChem; 2010 Oct; 5(10):1726-33. PubMed ID: 20815012
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Irreversible inhibition of type I dehydroquinase by substrates for type II dehydroquinase.
    Bello CG; Harris JM; Manthey MK; Coggins JR; Abell C
    Bioorg Med Chem Lett; 2000 Mar; 10(5):407-9. PubMed ID: 10743936
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The Mycobacterium tuberculosis shikimate pathway genes: evolutionary relationship between biosynthetic and catabolic 3-dehydroquinases.
    Garbe T; Servos S; Hawkins A; Dimitriadis G; Young D; Dougan G; Charles I
    Mol Gen Genet; 1991 Sep; 228(3):385-92. PubMed ID: 1910148
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Insights into Substrate Modification by Dehydratases from Type I Polyketide Synthases.
    Faille A; Gavalda S; Slama N; Lherbet C; Maveyraud L; Guillet V; Laval F; Quémard A; Mourey L; Pedelacq JD
    J Mol Biol; 2017 May; 429(10):1554-1569. PubMed ID: 28377293
    [TBL] [Abstract][Full Text] [Related]  

  • 12. 2-substituted-3-dehydroquinic acids as potent competitive inhibitors of type II dehydroquinase.
    Prazeres VF; Castedo L; Lamb H; Hawkins AR; González-Bello C
    ChemMedChem; 2009 Dec; 4(12):1980-4. PubMed ID: 19856378
    [No Abstract]   [Full Text] [Related]  

  • 13. Evidence that the active site in type II dehydroquinase from Streptomyces coelicolor is near the single tryptophan.
    Boam DJ; Price NC; Kelly SM; Krell T; Coggins JR
    Biochem Soc Trans; 1997 Feb; 25(1):348; replaces 93S. PubMed ID: 9147947
    [No Abstract]   [Full Text] [Related]  

  • 14. Inhibitors of types I and II dehydroquinase.
    Le Sann C; Gower MA; Abell AD
    Mini Rev Med Chem; 2004 Sep; 4(7):747-56. PubMed ID: 15379642
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Localization of the active site of type II dehydroquinases. Identification of a common arginine-containing motif in the two classes of dehydroquinases.
    Krell T; Horsburgh MJ; Cooper A; Kelly SM; Coggins JR
    J Biol Chem; 1996 Oct; 271(40):24492-7. PubMed ID: 8798709
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Crystal structures of Helicobacter pylori type II dehydroquinase inhibitor complexes: new directions for inhibitor design.
    Robinson DA; Stewart KA; Price NC; Chalk PA; Coggins JR; Lapthorn AJ
    J Med Chem; 2006 Feb; 49(4):1282-90. PubMed ID: 16480265
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Nanomolar competitive inhibitors of Mycobacterium tuberculosis and Streptomyces coelicolor type II dehydroquinase.
    Prazeres VF; Sánchez-Sixto C; Castedo L; Lamb H; Hawkins AR; Riboldi-Tunnicliffe A; Coggins JR; Lapthorn AJ; González-Bello C
    ChemMedChem; 2007 Feb; 2(2):194-207. PubMed ID: 17245805
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mechanistic basis of the inhibition of type II dehydroquinase by (2S)- and (2R)-2-benzyl-3-dehydroquinic acids.
    Lence E; Tizón L; Otero JM; Peón A; Prazeres VF; Llamas-Saiz AL; Fox GC; van Raaij MJ; Lamb H; Hawkins AR; González-Bello C
    ACS Chem Biol; 2013 Mar; 8(3):568-77. PubMed ID: 23198883
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The two types of 3-dehydroquinase have distinct structures but catalyze the same overall reaction.
    Gourley DG; Shrive AK; Polikarpov I; Krell T; Coggins JR; Hawkins AR; Isaacs NW; Sawyer L
    Nat Struct Biol; 1999 Jun; 6(6):521-5. PubMed ID: 10360352
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design and structural analysis of aromatic inhibitors of type II dehydroquinase from Mycobacterium tuberculosis.
    Howard NI; Dias MV; Peyrot F; Chen L; Schmidt MF; Blundell TL; Abell C
    ChemMedChem; 2015 Jan; 10(1):116-33. PubMed ID: 25234229
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.