BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

449 related articles for article (PubMed ID: 12391330)

  • 1. Permanent and panerythroid correction of murine beta thalassemia by multiple lentiviral integration in hematopoietic stem cells.
    Imren S; Payen E; Westerman KA; Pawliuk R; Fabry ME; Eaves CJ; Cavilla B; Wadsworth LD; Beuzard Y; Bouhassira EE; Russell R; London IM; Nagel RL; Leboulch P; Humphries RK
    Proc Natl Acad Sci U S A; 2002 Oct; 99(22):14380-5. PubMed ID: 12391330
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A novel transgenic mouse model produced from lentiviral germline integration for the study of beta-thalassemia gene therapy.
    Li W; Xie S; Guo X; Gong X; Wang S; Lin D; Zhang J; Ren Z; Huang S; Zeng F; Zeng Y
    Haematologica; 2008 Mar; 93(3):356-62. PubMed ID: 18268280
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Adeno-associated virus 2-mediated transduction and erythroid lineage-restricted long-term expression of the human beta-globin gene in hematopoietic cells from homozygous beta-thalassemic mice.
    Tan M; Qing K; Zhou S; Yoder MC; Srivastava A
    Mol Ther; 2001 Jun; 3(6):940-6. PubMed ID: 11407908
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Successful correction of the human Cooley's anemia beta-thalassemia major phenotype using a lentiviral vector flanked by the chicken hypersensitive site 4 chromatin insulator.
    Malik P; Arumugam PI; Yee JK; Puthenveetil G
    Ann N Y Acad Sci; 2005; 1054():238-49. PubMed ID: 16339671
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Gene Therapy for beta-thalassemia.
    Malik P; Arumugam PI
    Hematology Am Soc Hematol Educ Program; 2005; ():45-50. PubMed ID: 16304358
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The degree of phenotypic correction of murine beta -thalassemia intermedia following lentiviral-mediated transfer of a human gamma-globin gene is influenced by chromosomal position effects and vector copy number.
    Persons DA; Hargrove PW; Allay ER; Hanawa H; Nienhuis AW
    Blood; 2003 Mar; 101(6):2175-83. PubMed ID: 12411297
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Comparative analysis of FV vectors with human α- or β-globin gene regulatory elements for the correction of β-thalassemia.
    Morianos I; Siapati EK; Pongas G; Vassilopoulos G
    Gene Ther; 2012 Mar; 19(3):303-11. PubMed ID: 21734726
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Extended beta-globin locus control region elements promote consistent therapeutic expression of a gamma-globin lentiviral vector in murine beta-thalassemia.
    Hanawa H; Hargrove PW; Kepes S; Srivastava DK; Nienhuis AW; Persons DA
    Blood; 2004 Oct; 104(8):2281-90. PubMed ID: 15198957
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Lentiviral Transfer of γ-Globin with Fusion Gene NUP98-HOXA10HD Expands Hematopoietic Stem Cells and Ameliorates Murine β-Thalassemia.
    Zhao HF; Abraham A; Kim YS; Wang YD; Pestina T; Zhan J; Humphries K; Nienhuis AW; Persons DA
    Mol Ther; 2017 Mar; 25(3):593-605. PubMed ID: 28190779
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Progress toward the genetic treatment of the beta-thalassemias.
    Sadelain M; Lisowski L; Samakoglu S; Rivella S; May C; Riviere I
    Ann N Y Acad Sci; 2005; 1054():78-91. PubMed ID: 16339654
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Parallel assessment of globin lentiviral transfer in induced pluripotent stem cells and adult hematopoietic stem cells derived from the same transplanted β-thalassemia patient.
    Tubsuwan A; Abed S; Deichmann A; Kardel MD; Bartholomä C; Cheung A; Negre O; Kadri Z; Fucharoen S; von Kalle C; Payen E; Chrétien S; Schmidt M; Eaves CJ; Leboulch P; Maouche-Chrétien L
    Stem Cells; 2013 Sep; 31(9):1785-94. PubMed ID: 23712774
    [TBL] [Abstract][Full Text] [Related]  

  • 12. High-level erythroid lineage-directed gene expression using globin gene regulatory elements after lentiviral vector-mediated gene transfer into primitive human and murine hematopoietic cells.
    Hanawa H; Persons DA; Nienhuis AW
    Hum Gene Ther; 2002 Nov; 13(17):2007-16. PubMed ID: 12489996
    [TBL] [Abstract][Full Text] [Related]  

  • 13. High-level beta-globin expression and preferred intragenic integration after lentiviral transduction of human cord blood stem cells.
    Imren S; Fabry ME; Westerman KA; Pawliuk R; Tang P; Rosten PM; Nagel RL; Leboulch P; Eaves CJ; Humphries RK
    J Clin Invest; 2004 Oct; 114(7):953-62. PubMed ID: 15467834
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Amelioration of murine beta-thalassemia through drug selection of hematopoietic stem cells transduced with a lentiviral vector encoding both gamma-globin and the MGMT drug-resistance gene.
    Zhao H; Pestina TI; Nasimuzzaman M; Mehta P; Hargrove PW; Persons DA
    Blood; 2009 Jun; 113(23):5747-56. PubMed ID: 19365082
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Adeno-associated virus 2-mediated transduction and erythroid lineage-restricted expression from parvovirus B19p6 promoter in primary human hematopoietic progenitor cells.
    Kurpad C; Mukherjee P; Wang XS; Ponnazhagan S; Li L; Yoder MC; Srivastava A
    J Hematother Stem Cell Res; 1999 Dec; 8(6):585-92. PubMed ID: 10645765
    [TBL] [Abstract][Full Text] [Related]  

  • 16. [Retroviral transfer of a human beta-globin gene linked to beta locus control region hypersensitive site 2 into murine hematopoietic stem cells].
    Zhai J; Liu D; Wang J
    Zhonghua Yi Xue Za Zhi; 1999 Feb; 79(2):121-4. PubMed ID: 11601018
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Correction of sickle cell disease in transgenic mouse models by gene therapy.
    Pawliuk R; Westerman KA; Fabry ME; Payen E; Tighe R; Bouhassira EE; Acharya SA; Ellis J; London IM; Eaves CJ; Humphries RK; Beuzard Y; Nagel RL; Leboulch P
    Science; 2001 Dec; 294(5550):2368-71. PubMed ID: 11743206
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Therapeutic hemoglobin levels after gene transfer in β-thalassemia mice and in hematopoietic cells of β-thalassemia and sickle cells disease patients.
    Breda L; Casu C; Gardenghi S; Bianchi N; Cartegni L; Narla M; Yazdanbakhsh K; Musso M; Manwani D; Little J; Gardner LB; Kleinert DA; Prus E; Fibach E; Grady RW; Giardina PJ; Gambari R; Rivella S
    PLoS One; 2012; 7(3):e32345. PubMed ID: 22479321
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A human beta-globin gene fused to the human beta-globin locus control region is expressed at high levels in erythroid cells of mice engrafted with retrovirus-transduced hematopoietic stem cells.
    Plavec I; Papayannopoulou T; Maury C; Meyer F
    Blood; 1993 Mar; 81(5):1384-92. PubMed ID: 8443396
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A novel murine model of Cooley anemia and its rescue by lentiviral-mediated human beta-globin gene transfer.
    Rivella S; May C; Chadburn A; Rivière I; Sadelain M
    Blood; 2003 Apr; 101(8):2932-9. PubMed ID: 12480689
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.