BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

187 related articles for article (PubMed ID: 12392815)

  • 1. Pro-apoptotic actions of exisulind and CP461 in SW480 colon tumor cells involve beta-catenin and cyclin D1 down-regulation.
    Li H; Liu L; David ML; Whitehead CM; Chen M; Fetter JR; Sperl GJ; Pamukcu R; Thompson WJ
    Biochem Pharmacol; 2002 Nov; 64(9):1325-36. PubMed ID: 12392815
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Sulindac metabolites induce caspase- and proteasome-dependent degradation of beta-catenin protein in human colon cancer cells.
    Rice PL; Kelloff J; Sullivan H; Driggers LJ; Beard KS; Kuwada S; Piazza G; Ahnen DJ
    Mol Cancer Ther; 2003 Sep; 2(9):885-92. PubMed ID: 14555707
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cyclic GMP-dependent protein kinase activation and induction by exisulind and CP461 in colon tumor cells.
    Liu L; Li H; Underwood T; Lloyd M; David M; Sperl G; Pamukcu R; Thompson WJ
    J Pharmacol Exp Ther; 2001 Nov; 299(2):583-92. PubMed ID: 11602670
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Exisulind induction of apoptosis involves guanosine 3',5'-cyclic monophosphate phosphodiesterase inhibition, protein kinase G activation, and attenuated beta-catenin.
    Thompson WJ; Piazza GA; Li H; Liu L; Fetter J; Zhu B; Sperl G; Ahnen D; Pamukcu R
    Cancer Res; 2000 Jul; 60(13):3338-42. PubMed ID: 10910034
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synergistic effects of acyclic retinoid and OSI-461 on growth inhibition and gene expression in human hepatoma cells.
    Shimizu M; Suzui M; Deguchi A; Lim JT; Xiao D; Hayes JH; Papadopoulos KP; Weinstein IB
    Clin Cancer Res; 2004 Oct; 10(19):6710-21. PubMed ID: 15475462
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Benzylamide sulindac analogues induce changes in cell shape, loss of microtubules and G(2)-M arrest in a chronic lymphocytic leukemia (CLL) cell line and apoptosis in primary CLL cells.
    Moon EY; Lerner A
    Cancer Res; 2002 Oct; 62(20):5711-9. PubMed ID: 12384529
    [TBL] [Abstract][Full Text] [Related]  

  • 7. beta-Catenin signaling: therapeutic strategies in oncology.
    Li H; Pamukcu R; Thompson WJ
    Cancer Biol Ther; 2002; 1(6):621-5. PubMed ID: 12642683
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Quercetin inhibit human SW480 colon cancer growth in association with inhibition of cyclin D1 and survivin expression through Wnt/beta-catenin signaling pathway.
    Shan BE; Wang MX; Li RQ
    Cancer Invest; 2009 Jul; 27(6):604-12. PubMed ID: 19440933
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Activation of protein kinase G is sufficient to induce apoptosis and inhibit cell migration in colon cancer cells.
    Deguchi A; Thompson WJ; Weinstein IB
    Cancer Res; 2004 Jun; 64(11):3966-73. PubMed ID: 15173009
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Essential role of the cGMP/PKG signaling pathway in regulating the proliferation and survival of human renal carcinoma cells.
    Ren Y; Zheng J; Yao X; Weng G; Wu L
    Int J Mol Med; 2014 Nov; 34(5):1430-8. PubMed ID: 25244411
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Vasodilator-stimulated phosphoprotein (VASP) phosphorylation provides a biomarker for the action of exisulind and related agents that activate protein kinase G.
    Deguchi A; Soh JW; Li H; Pamukcu R; Thompson WJ; Weinstein IB
    Mol Cancer Ther; 2002 Aug; 1(10):803-9. PubMed ID: 12492113
    [TBL] [Abstract][Full Text] [Related]  

  • 12. CP248, a derivative of exisulind, causes growth inhibition, mitotic arrest, and abnormalities in microtubule polymerization in glioma cells.
    Yoon JT; Palazzo AF; Xiao D; Delohery TM; Warburton PE; Bruce JN; Thompson WJ; Sperl G; Whitehead C; Fetter J; Pamukcu R; Gundersen GG; Weinstein IB
    Mol Cancer Ther; 2002 Apr; 1(6):393-404. PubMed ID: 12477052
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The ubiquitin-proteasome pathway and serine kinase activity modulate adenomatous polyposis coli protein-mediated regulation of beta-catenin-lymphocyte enhancer-binding factor signaling.
    Easwaran V; Song V; Polakis P; Byers S
    J Biol Chem; 1999 Jun; 274(23):16641-5. PubMed ID: 10347231
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Alpha-tocopheryl succinate sensitizes human colon cancer cells to exisulind-induced apoptosis.
    Lim SJ; Lee YJ; Park DH; Lee E; Choi MK; Park W; Chun KH; Choi HG; Cho JS
    Apoptosis; 2007 Feb; 12(2):423-31. PubMed ID: 17191116
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Sulindac sulfone is most effective in modulating beta-catenin-mediated transcription in cells with mutant APC.
    Chang WC; Everley LC; Pfeiffer GR; Cooper HS; Barusevicius A; Clapper ML
    Ann N Y Acad Sci; 2005 Nov; 1059():41-55. PubMed ID: 16382042
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Peroxisome proliferator-activated receptor gamma activation can regulate beta-catenin levels via a proteasome-mediated and adenomatous polyposis coli-independent pathway.
    Sharma C; Pradeep A; Wong L; Rana A; Rana B
    J Biol Chem; 2004 Aug; 279(34):35583-94. PubMed ID: 15190077
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Exisulind and guanylyl cyclase C induce distinct antineoplastic signaling mechanisms in human colon cancer cells.
    Pitari GM; Li T; Baksh RI; Waldman SA
    Mol Cancer Ther; 2006 May; 5(5):1190-6. PubMed ID: 16731751
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Exisulind, a novel proapoptotic drug, inhibits rat urinary bladder tumorigenesis.
    Piazza GA; Thompson WJ; Pamukcu R; Alila HW; Whitehead CM; Liu L; Fetter JR; Gresh WE; Klein-Szanto AJ; Farnell DR; Eto I; Grubbs CJ
    Cancer Res; 2001 May; 61(10):3961-8. PubMed ID: 11358813
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Beta2-adrenergic receptor agonists and cAMP arrest human cultured airway smooth muscle cells in the G(1) phase of the cell cycle: role of proteasome degradation of cyclin D1.
    Stewart AG; Harris T; Fernandes DJ; Schachte LC; Koutsoubos V; Guida E; Ravenhall CE; Vadiveloo P; Wilson JW
    Mol Pharmacol; 1999 Nov; 56(5):1079-86. PubMed ID: 10531416
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Regulation of S33/S37 phosphorylated beta-catenin in normal and transformed cells.
    Sadot E; Conacci-Sorrell M; Zhurinsky J; Shnizer D; Lando Z; Zharhary D; Kam Z; Ben-Ze'ev A; Geiger B
    J Cell Sci; 2002 Jul; 115(Pt 13):2771-80. PubMed ID: 12077367
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.