BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

194 related articles for article (PubMed ID: 12399470)

  • 1. p105.Ikappa Bgamma and prototypical Ikappa Bs use a similar mechanism to bind but a different mechanism to regulate the subcellular localization of NF-kappa B.
    Moorthy AK; Ghosh G
    J Biol Chem; 2003 Jan; 278(1):556-66. PubMed ID: 12399470
    [TBL] [Abstract][Full Text] [Related]  

  • 2. NF-kappaB p105 is a target of IkappaB kinases and controls signal induction of Bcl-3-p50 complexes.
    Heissmeyer V; Krappmann D; Wulczyn FG; Scheidereit C
    EMBO J; 1999 Sep; 18(17):4766-78. PubMed ID: 10469655
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Characterization of ES cells deficient for the p105 precursor (NF-kappa B1): role of p50 NLS.
    Ishikawa H; Ryseck RP; Bravo R
    Oncogene; 1996 Jul; 13(2):255-63. PubMed ID: 8710364
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The Nfkb1 and Nfkb2 proteins p105 and p100 function as the core of high-molecular-weight heterogeneous complexes.
    Savinova OV; Hoffmann A; Ghosh G
    Mol Cell; 2009 Jun; 34(5):591-602. PubMed ID: 19524538
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Solvent exposed non-contacting amino acids play a critical role in NF-kappaB/IkappaBalpha complex formation.
    Huxford T; Mishler D; Phelps CB; Huang DB; Sengchanthalangsy LL; Reeves R; Hughes CA; Komives EA; Ghosh G
    J Mol Biol; 2002 Dec; 324(4):587-97. PubMed ID: 12460563
    [TBL] [Abstract][Full Text] [Related]  

  • 6. IkappaBbeta, but not IkappaBalpha, functions as a classical cytoplasmic inhibitor of NF-kappaB dimers by masking both NF-kappaB nuclear localization sequences in resting cells.
    Malek S; Chen Y; Huxford T; Ghosh G
    J Biol Chem; 2001 Nov; 276(48):45225-35. PubMed ID: 11571291
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mechanisms of ubiquitin-mediated, limited processing of the NF-kappaB1 precursor protein p105.
    Ciechanover A; Gonen H; Bercovich B; Cohen S; Fajerman I; Israël A; Mercurio F; Kahana C; Schwartz AL; Iwai K; Orian A
    Biochimie; 2001; 83(3-4):341-9. PubMed ID: 11295495
    [TBL] [Abstract][Full Text] [Related]  

  • 8. KappaB-Ras binds to the unique insert within the ankyrin repeat domain of IkappaBbeta and regulates cytoplasmic retention of IkappaBbeta x NF-kappaB complexes.
    Chen Y; Wu J; Ghosh G
    J Biol Chem; 2003 Jun; 278(25):23101-6. PubMed ID: 12672800
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Shared pathways of IkappaB kinase-induced SCF(betaTrCP)-mediated ubiquitination and degradation for the NF-kappaB precursor p105 and IkappaBalpha.
    Heissmeyer V; Krappmann D; Hatada EN; Scheidereit C
    Mol Cell Biol; 2001 Feb; 21(4):1024-35. PubMed ID: 11158290
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Induced fit, folding, and recognition of the NF-kappaB-nuclear localization signals by IkappaBalpha and IkappaBbeta.
    Lätzer J; Papoian GA; Prentiss MC; Komives EA; Wolynes PG
    J Mol Biol; 2007 Mar; 367(1):262-74. PubMed ID: 17257619
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ikappa Balpha functions through direct contacts with the nuclear localization signals and the DNA binding sequences of NF-kappaB.
    Malek S; Huxford T; Ghosh G
    J Biol Chem; 1998 Sep; 273(39):25427-35. PubMed ID: 9738011
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The N-terminal domain of IkappaB alpha masks the nuclear localization signal(s) of p50 and c-Rel homodimers.
    Latimer M; Ernst MK; Dunn LL; Drutskaya M; Rice NR
    Mol Cell Biol; 1998 May; 18(5):2640-9. PubMed ID: 9566883
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Casper/c-FLIP is physically and functionally associated with NF-kappaB1 p105.
    Li Z; Zhang J; Chen D; Shu HB
    Biochem Biophys Res Commun; 2003 Oct; 309(4):980-5. PubMed ID: 13679070
    [TBL] [Abstract][Full Text] [Related]  

  • 14. IkappaBalpha and IkappaBalpha /NF-kappa B complexes are retained in the cytoplasm through interaction with a novel partner, RasGAP SH3-binding protein 2.
    Prigent M; Barlat I; Langen H; Dargemont C
    J Biol Chem; 2000 Nov; 275(46):36441-9. PubMed ID: 10969074
    [TBL] [Abstract][Full Text] [Related]  

  • 15. All three IkappaB isoforms and most Rel family members are stably associated with the IkappaB kinase 1/2 complex.
    Heilker R; Freuler F; Pulfer R; Di Padova F; Eder J
    Eur J Biochem; 1999 Jan; 259(1-2):253-61. PubMed ID: 9914500
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Interaction of the C-terminal region of p105 with the nuclear localisation signal of p50 is required for inhibition of NF-kappa B DNA binding activity.
    Matthews JR; Watson E; Buckley S; Hay RT
    Nucleic Acids Res; 1993 Sep; 21(19):4516-23. PubMed ID: 7694229
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mechanism for biphasic rel A. NF-kappaB1 nuclear translocation in tumor necrosis factor alpha-stimulated hepatocytes.
    Han Y; Brasier AR
    J Biol Chem; 1997 Apr; 272(15):9825-32. PubMed ID: 9092517
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Thermodynamics reveal that helix four in the NLS of NF-kappaB p65 anchors IkappaBalpha, forming a very stable complex.
    Bergqvist S; Croy CH; Kjaergaard M; Huxford T; Ghosh G; Komives EA
    J Mol Biol; 2006 Jul; 360(2):421-34. PubMed ID: 16756995
    [TBL] [Abstract][Full Text] [Related]  

  • 19. p100/IκBδ sequesters and inhibits NF-κB through kappaBsome formation.
    Tao Z; Fusco A; Huang DB; Gupta K; Young Kim D; Ware CF; Van Duyne GD; Ghosh G
    Proc Natl Acad Sci U S A; 2014 Nov; 111(45):15946-51. PubMed ID: 25349408
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The precursor of NF-kappa B p50 has I kappa B-like functions.
    Rice NR; MacKichan ML; Israël A
    Cell; 1992 Oct; 71(2):243-53. PubMed ID: 1423592
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.