BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

344 related articles for article (PubMed ID: 12403834)

  • 1. Synaptosome-associated protein of 25 kilodaltons modulates Kv2.1 voltage-dependent K(+) channels in neuroendocrine islet beta-cells through an interaction with the channel N terminus.
    MacDonald PE; Wang G; Tsuk S; Dodo C; Kang Y; Tang L; Wheeler MB; Cattral MS; Lakey JR; Salapatek AM; Lotan I; Gaisano HY
    Mol Endocrinol; 2002 Nov; 16(11):2452-61. PubMed ID: 12403834
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Syntaxin 1A binds to the cytoplasmic C terminus of Kv2.1 to regulate channel gating and trafficking.
    Leung YM; Kang Y; Gao X; Xia F; Xie H; Sheu L; Tsuk S; Lotan I; Tsushima RG; Gaisano HY
    J Biol Chem; 2003 May; 278(19):17532-8. PubMed ID: 12621036
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Target soluble N-ethylmaleimide-sensitive factor attachment protein receptors (t-SNAREs) differently regulate activation and inactivation gating of Kv2.2 and Kv2.1: Implications on pancreatic islet cell Kv channels.
    Wolf-Goldberg T; Michaelevski I; Sheu L; Gaisano HY; Chikvashvili D; Lotan I
    Mol Pharmacol; 2006 Sep; 70(3):818-28. PubMed ID: 16754785
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Open form of syntaxin-1A is a more potent inhibitor than wild-type syntaxin-1A of Kv2.1 channels.
    Leung YM; Kang Y; Xia F; Sheu L; Gao X; Xie H; Tsushima RG; Gaisano HY
    Biochem J; 2005 Apr; 387(Pt 1):195-202. PubMed ID: 15518587
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Direct interaction of target SNAREs with the Kv2.1 channel. Modal regulation of channel activation and inactivation gating.
    Michaelevski I; Chikvashvili D; Tsuk S; Singer-Lahat D; Kang Y; Linial M; Gaisano HY; Fili O; Lotan I
    J Biol Chem; 2003 Sep; 278(36):34320-30. PubMed ID: 12807875
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Members of the Kv1 and Kv2 voltage-dependent K(+) channel families regulate insulin secretion.
    MacDonald PE; Ha XF; Wang J; Smukler SR; Sun AM; Gaisano HY; Salapatek AM; Backx PH; Wheeler MB
    Mol Endocrinol; 2001 Aug; 15(8):1423-35. PubMed ID: 11463864
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Kv2.1 channel activation and inactivation is influenced by physical interactions of both syntaxin 1A and the syntaxin 1A/soluble N-ethylmaleimide-sensitive factor-25 (t-SNARE) complex with the C terminus of the channel.
    Tsuk S; Michaelevski I; Bentley GN; Joho RH; Chikvashvili D; Lotan I
    Mol Pharmacol; 2005 Feb; 67(2):480-8. PubMed ID: 15525758
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of Kv2.1 voltage-dependent K+ channels in pancreatic beta-cells enhances glucose-dependent insulin secretion.
    MacDonald PE; Sewing S; Wang J; Joseph JW; Smukler SR; Sakellaropoulos G; Wang J; Saleh MC; Chan CB; Tsushima RG; Salapatek AM; Wheeler MB
    J Biol Chem; 2002 Nov; 277(47):44938-45. PubMed ID: 12270920
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Disruption of pancreatic beta-cell lipid rafts modifies Kv2.1 channel gating and insulin exocytosis.
    Xia F; Gao X; Kwan E; Lam PP; Chan L; Sy K; Sheu L; Wheeler MB; Gaisano HY; Tsushima RG
    J Biol Chem; 2004 Jun; 279(23):24685-91. PubMed ID: 15073181
    [TBL] [Abstract][Full Text] [Related]  

  • 10. SNAP-25, a SNARE protein, inhibits two types of K channels in esophageal smooth muscle.
    Ji J; Salapatek AM; Lau H; Wang G; Gaisano HY; Diamant NE
    Gastroenterology; 2002 Apr; 122(4):994-1006. PubMed ID: 11910352
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Modulation of L-type Ca(2+) channels by distinct domains within SNAP-25.
    Ji J; Yang SN; Huang X; Li X; Sheu L; Diamant N; Berggren PO; Gaisano HY
    Diabetes; 2002 May; 51(5):1425-36. PubMed ID: 11978639
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Botulinum neurotoxin A and neurotoxin E cleavage products of synaptosome-associated protein of 25 kd exhibit distinct actions on pancreatic islet beta-cell Kv2.1 channel gating.
    He Y; Elias CL; Huang YC; Gao X; Leung YM; Kang Y; Xie H; Chaddock JA; Tsushima RG; Gaisano HY
    Pancreas; 2008 Jan; 36(1):10-7. PubMed ID: 18192874
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Modulation of Kv2.1 channel gating and TEA sensitivity by distinct domains of SNAP-25.
    He Y; Kang Y; Leung YM; Xia F; Gao X; Xie H; Gaisano HY; Tsushima RG
    Biochem J; 2006 Jun; 396(2):363-9. PubMed ID: 16478442
    [TBL] [Abstract][Full Text] [Related]  

  • 14. SNAREing voltage-gated K+ and ATP-sensitive K+ channels: tuning beta-cell excitability with syntaxin-1A and other exocytotic proteins.
    Leung YM; Kwan EP; Ng B; Kang Y; Gaisano HY
    Endocr Rev; 2007 Oct; 28(6):653-63. PubMed ID: 17878408
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The 25-kDa synaptosome-associated protein (SNAP-25) binds and inhibits delayed rectifier potassium channels in secretory cells.
    Ji J; Tsuk S; Salapatek AM; Huang X; Chikvashvili D; Pasyk EA; Kang Y; Sheu L; Tsushima R; Diamant N; Trimble WS; Lotan I; Gaisano HY
    J Biol Chem; 2002 Jun; 277(23):20195-204. PubMed ID: 11925439
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The voltage-dependent potassium channel subunit Kv2.1 regulates insulin secretion from rodent and human islets independently of its electrical function.
    Dai XQ; Manning Fox JE; Chikvashvili D; Casimir M; Plummer G; Hajmrle C; Spigelman AF; Kin T; Singer-Lahat D; Kang Y; Shapiro AM; Gaisano HY; Lotan I; Macdonald PE
    Diabetologia; 2012 Jun; 55(6):1709-20. PubMed ID: 22411134
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Delayed-rectifier (KV2.1) regulation of pancreatic beta-cell calcium responses to glucose: inhibitor specificity and modeling.
    Tamarina NA; Kuznetsov A; Fridlyand LE; Philipson LH
    Am J Physiol Endocrinol Metab; 2005 Oct; 289(4):E578-85. PubMed ID: 16014354
    [TBL] [Abstract][Full Text] [Related]  

  • 18. SNAP-25(1-180) enhances insulin secretion by blocking Kv2.1 channels in rat pancreatic islet beta-cells.
    Zhuang GQ; Wu W; Liu F; Ma JL; Luo YX; Xiao ZX; Liu Y; Wang W; He Y
    Biochem Biophys Res Commun; 2009 Feb; 379(4):812-6. PubMed ID: 19103161
    [TBL] [Abstract][Full Text] [Related]  

  • 19. R-type voltage-gated Ca(2+) channel interacts with synaptic proteins and recruits synaptotagmin to the plasma membrane of Xenopus oocytes.
    Cohen R; Atlas D
    Neuroscience; 2004; 128(4):831-41. PubMed ID: 15464290
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The Roles of N- and C-terminal determinants in the activation of the Kv2.1 potassium channel.
    Ju M; Stevens L; Leadbitter E; Wray D
    J Biol Chem; 2003 Apr; 278(15):12769-78. PubMed ID: 12560340
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.