BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

199 related articles for article (PubMed ID: 12403977)

  • 1. From chemical to drug: neurodegeneration drug screening and the ethics of clinical trials.
    Heemskerk J; Tobin AJ; Ravina B
    Nat Neurosci; 2002 Nov; 5 Suppl():1027-9. PubMed ID: 12403977
    [No Abstract]   [Full Text] [Related]  

  • 2. Exploratory clinical testing of neuroscience drugs.
    Choi DW
    Nat Neurosci; 2002 Nov; 5 Suppl():1023-5. PubMed ID: 12403975
    [No Abstract]   [Full Text] [Related]  

  • 3. [Drug testing today].
    Domschke S; Domschke W
    Fortschr Med; 1981 Jun; 99(21):814-8. PubMed ID: 7250872
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The adult human brain in preclinical drug development.
    Dragunow M
    Nat Rev Drug Discov; 2008 Aug; 7(8):659-66. PubMed ID: 18617887
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Neurotrophins: from enthusiastic expectations through sobering experiences to rational therapeutic approaches.
    Thoenen H; Sendtner M
    Nat Neurosci; 2002 Nov; 5 Suppl():1046-50. PubMed ID: 12403983
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Missing results might have rung warning bell over trial drug.
    Pearson H
    Nature; 2006 Oct; 443(7113):730-1. PubMed ID: 17051171
    [No Abstract]   [Full Text] [Related]  

  • 7. Invertebrate animal models of diseases as screening tools in drug discovery.
    Ségalat L
    ACS Chem Biol; 2007 Apr; 2(4):231-6. PubMed ID: 17455900
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Need to improve clinical trials in rare neurodegenerative disorders.
    Puopolo M; Pocchiari M
    Ann Ist Super Sanita; 2011; 47(1):55-9. PubMed ID: 21430340
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The future of drug safety testing: expanding the view and narrowing the focus.
    Stevens JL; Baker TK
    Drug Discov Today; 2009 Feb; 14(3-4):162-7. PubMed ID: 19100337
    [TBL] [Abstract][Full Text] [Related]  

  • 10. High-risk molecules or insufficient scientific data?
    Mignot A
    Clin Pharmacol Ther; 2008 Feb; 83(2):365-7. PubMed ID: 18091760
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Miracles and molecules--progress in spinal cord repair.
    Blight AR
    Nat Neurosci; 2002 Nov; 5 Suppl():1051-4. PubMed ID: 12403984
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Changing requirements for evaluation of pharmacologic agents.
    Chesney RW; Christensen ML
    Pediatrics; 2004 Apr; 113(4 Suppl):1128-32. PubMed ID: 15060209
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Drug development. Biotech thinking comes to academic medical centers.
    Alper J
    Science; 2003 Feb; 299(5611):1303-5. PubMed ID: 12610271
    [No Abstract]   [Full Text] [Related]  

  • 14. Growth factor treatment of neurodegenerative disorders: new developments pave the way for clinical success.
    Rosenblad C
    IDrugs; 2004 Mar; 7(3):243-8. PubMed ID: 15011099
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Drug Development for Neurodegenerative Diseases--a marcus evans conference. Expediting drugs to the market for neurodegenerative disease indications through novel translational efforts, regulatory clarity, and sound trial design. 7-8 April 2009, Boston, MA, USA.
    Morimoto B
    IDrugs; 2009 Jun; 12(6):349-52. PubMed ID: 19517313
    [No Abstract]   [Full Text] [Related]  

  • 16. Recent clinical failures in Parkinson's disease with apoptosis inhibitors underline the need for a paradigm shift in drug discovery for neurodegenerative diseases.
    Waldmeier P; Bozyczko-Coyne D; Williams M; Vaught JL
    Biochem Pharmacol; 2006 Nov; 72(10):1197-206. PubMed ID: 16901468
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Phase 0 trials: are they ethically challenged?
    Hill TP
    Clin Cancer Res; 2007 Feb; 13(3):783-4. PubMed ID: 17289866
    [No Abstract]   [Full Text] [Related]  

  • 18. [Fundamental principles of clinical trials].
    Skarke C; Geisslinger G
    Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz; 2005 Apr; 48(4):401-7. PubMed ID: 15830250
    [TBL] [Abstract][Full Text] [Related]  

  • 19. [Clinical demonstration of the action of liver drugs].
    Einsiedel-Schömer W
    Z Allgemeinmed; 1973 Oct; 49(30):1452-5. PubMed ID: 4588532
    [No Abstract]   [Full Text] [Related]  

  • 20. Toxicogenomics in drug discovery: from preclinical studies to clinical trials.
    Yang Y; Blomme EA; Waring JF
    Chem Biol Interact; 2004 Nov; 150(1):71-85. PubMed ID: 15522262
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.