BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

573 related articles for article (PubMed ID: 12406221)

  • 1. Overexpression of inhA, but not kasA, confers resistance to isoniazid and ethionamide in Mycobacterium smegmatis, M. bovis BCG and M. tuberculosis.
    Larsen MH; Vilchèze C; Kremer L; Besra GS; Parsons L; Salfinger M; Heifets L; Hazbon MH; Alland D; Sacchettini JC; Jacobs WR
    Mol Microbiol; 2002 Oct; 46(2):453-66. PubMed ID: 12406221
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Isoniazid affects multiple components of the type II fatty acid synthase system of Mycobacterium tuberculosis.
    Slayden RA; Lee RE; Barry CE
    Mol Microbiol; 2000 Nov; 38(3):514-25. PubMed ID: 11069675
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of InhA activity, but not KasA activity, induces formation of a KasA-containing complex in mycobacteria.
    Kremer L; Dover LG; Morbidoni HR; Vilchèze C; Maughan WN; Baulard A; Tu SC; Honoré N; Deretic V; Sacchettini JC; Locht C; Jacobs WR; Besra GS
    J Biol Chem; 2003 Jun; 278(23):20547-54. PubMed ID: 12654922
    [TBL] [Abstract][Full Text] [Related]  

  • 4. inhA, a gene encoding a target for isoniazid and ethionamide in Mycobacterium tuberculosis.
    Banerjee A; Dubnau E; Quemard A; Balasubramanian V; Um KS; Wilson T; Collins D; de Lisle G; Jacobs WR
    Science; 1994 Jan; 263(5144):227-30. PubMed ID: 8284673
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Altered NADH/NAD+ ratio mediates coresistance to isoniazid and ethionamide in mycobacteria.
    Vilchèze C; Weisbrod TR; Chen B; Kremer L; Hazbón MH; Wang F; Alland D; Sacchettini JC; Jacobs WR
    Antimicrob Agents Chemother; 2005 Feb; 49(2):708-20. PubMed ID: 15673755
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Exclusive mutations related to isoniazid and ethionamide resistance among Mycobacterium tuberculosis isolates from Korea.
    Lee H; Cho SN; Bang HE; Lee JH; Bai GH; Kim SJ; Kim JD
    Int J Tuberc Lung Dis; 2000 May; 4(5):441-7. PubMed ID: 10815738
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The mabA gene from the inhA operon of Mycobacterium tuberculosis encodes a 3-ketoacyl reductase that fails to confer isoniazid resistance.
    Banerjee A; Sugantino M; Sacchettini JC; Jacobs WR
    Microbiology (Reading); 1998 Oct; 144 ( Pt 10)():2697-2704. PubMed ID: 9802011
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Resistance to Isoniazid and Ethionamide in Mycobacterium tuberculosis: Genes, Mutations, and Causalities.
    Vilchèze C; Jacobs WR
    Microbiol Spectr; 2014 Aug; 2(4):MGM2-0014-2013. PubMed ID: 26104204
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Genotypic Analysis of Genes Associated with Independent Resistance and Cross-Resistance to Isoniazid and Ethionamide in Mycobacterium tuberculosis Clinical Isolates.
    Rueda J; Realpe T; Mejia GI; Zapata E; Rozo JC; Ferro BE; Robledo J
    Antimicrob Agents Chemother; 2015 Dec; 59(12):7805-10. PubMed ID: 26369965
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inactivation of the inhA-encoded fatty acid synthase II (FASII) enoyl-acyl carrier protein reductase induces accumulation of the FASI end products and cell lysis of Mycobacterium smegmatis.
    Vilchèze C; Morbidoni HR; Weisbrod TR; Iwamoto H; Kuo M; Sacchettini JC; Jacobs WR
    J Bacteriol; 2000 Jul; 182(14):4059-67. PubMed ID: 10869086
    [TBL] [Abstract][Full Text] [Related]  

  • 11. ethA, inhA, and katG loci of ethionamide-resistant clinical Mycobacterium tuberculosis isolates.
    Morlock GP; Metchock B; Sikes D; Crawford JT; Cooksey RC
    Antimicrob Agents Chemother; 2003 Dec; 47(12):3799-805. PubMed ID: 14638486
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Comparative analysis of mycobacterial NADH pyrophosphatase isoforms reveals a novel mechanism for isoniazid and ethionamide inactivation.
    Wang XD; Gu J; Wang T; Bi LJ; Zhang ZP; Cui ZQ; Wei HP; Deng JY; Zhang XE
    Mol Microbiol; 2011 Dec; 82(6):1375-91. PubMed ID: 22026918
    [TBL] [Abstract][Full Text] [Related]  

  • 13. [Establishment and drug susceptibility test of isoniazid resistant Mycobacterium smegmatis].
    Jia PP; Zhao LL; Li XY; Zhang Q; Liu ZL; Wang X; Yu LY; Zhao LX; Cen S
    Yao Xue Xue Bao; 2011 Apr; 46(4):377-82. PubMed ID: 21751489
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ethionamide cross- and co-resistance in children with isoniazid-resistant tuberculosis.
    Schaaf HS; Victor TC; Venter A; Brittle W; Jordaan AM; Hesseling AC; Marais BJ; van Helden PD; Donald PR
    Int J Tuberc Lung Dis; 2009 Nov; 13(11):1355-9. PubMed ID: 19861006
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Precise null deletion mutations of the mycothiol synthesis genes reveal their role in isoniazid and ethionamide resistance in Mycobacterium smegmatis.
    Xu X; Vilchèze C; Av-Gay Y; Gómez-Velasco A; Jacobs WR
    Antimicrob Agents Chemother; 2011 Jul; 55(7):3133-9. PubMed ID: 21502624
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Can inhA mutation predict ethionamide resistance?
    Vadwai V; Ajbani K; Jose M; Vineeth VP; Nikam C; Deshmukh M; Shetty A; Soman R; Rodrigues C
    Int J Tuberc Lung Dis; 2013 Jan; 17(1):129-30. PubMed ID: 23146620
    [TBL] [Abstract][Full Text] [Related]  

  • 17. [Characterization of the katG, inhA, ahpC, kasA, and oxyR gene mutations in isoniazid-resistant and susceptible strain of Mycobacterium tuberculosis by automated DNA sequencing].
    Chen X; Ma Y; Jin Q; Jiang GL; Li CY; Wang Q
    Zhonghua Jie He He Hu Xi Za Zhi; 2005 Apr; 28(4):250-3. PubMed ID: 15854436
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Fast-growing, non-infectious and intracellularly surviving drug-resistant Mycobacterium aurum: a model for high-throughput antituberculosis drug screening.
    Gupta A; Bhakta S; Kundu S; Gupta M; Srivastava BS; Srivastava R
    J Antimicrob Chemother; 2009 Oct; 64(4):774-81. PubMed ID: 19656786
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Activation of the pro-drug ethionamide is regulated in mycobacteria.
    Baulard AR; Betts JC; Engohang-Ndong J; Quan S; McAdam RA; Brennan PJ; Locht C; Besra GS
    J Biol Chem; 2000 Sep; 275(36):28326-31. PubMed ID: 10869356
    [TBL] [Abstract][Full Text] [Related]  

  • 20. High-level resistance to isoniazid and ethionamide in multidrug-resistant Mycobacterium tuberculosis of the Lisboa family is associated with inhA double mutations.
    Machado D; Perdigão J; Ramos J; Couto I; Portugal I; Ritter C; Boettger EC; Viveiros M
    J Antimicrob Chemother; 2013 Aug; 68(8):1728-32. PubMed ID: 23539241
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 29.