BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

153 related articles for article (PubMed ID: 12409610)

  • 1. The catalytic cycle of beta -lactam synthetase observed by x-ray crystallographic snapshots.
    Miller MT; Bachmann BO; Townsend CA; Rosenzweig AC
    Proc Natl Acad Sci U S A; 2002 Nov; 99(23):14752-7. PubMed ID: 12409610
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Kinetic mechanism of the beta-lactam synthetase of Streptomyces clavuligerus.
    Bachmann BO; Townsend CA
    Biochemistry; 2000 Sep; 39(37):11187-93. PubMed ID: 10985764
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structure of beta-lactam synthetase reveals how to synthesize antibiotics instead of asparagine.
    Miller MT; Bachmann BO; Townsend CA; Rosenzweig AC
    Nat Struct Biol; 2001 Aug; 8(8):684-9. PubMed ID: 11473258
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Crystal structure of carbapenam synthetase (CarA).
    Miller MT; Gerratana B; Stapon A; Townsend CA; Rosenzweig AC
    J Biol Chem; 2003 Oct; 278(42):40996-1002. PubMed ID: 12890666
    [TBL] [Abstract][Full Text] [Related]  

  • 5. beta-Lactam synthetase: a new biosynthetic enzyme.
    Bachmann BO; Li R; Townsend CA
    Proc Natl Acad Sci U S A; 1998 Aug; 95(16):9082-6. PubMed ID: 9689037
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A conserved tyrosyl-glutamyl catalytic dyad in evolutionarily linked enzymes: carbapenam synthetase and beta-lactam synthetase.
    Raber ML; Arnett SO; Townsend CA
    Biochemistry; 2009 Jun; 48(22):4959-71. PubMed ID: 19371088
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Investigation of the catalytic site within the ATP-grasp domain of Clostridium symbiosum pyruvate phosphate dikinase.
    Ye D; Wei M; McGuire M; Huang K; Kapadia G; Herzberg O; Martin BM; Dunaway-Mariano D
    J Biol Chem; 2001 Oct; 276(40):37630-9. PubMed ID: 11468288
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dissection of the stepwise mechanism to beta-lactam formation and elucidation of a rate-determining conformational change in beta-lactam synthetase.
    Raber ML; Freeman MF; Townsend CA
    J Biol Chem; 2009 Jan; 284(1):207-217. PubMed ID: 18955494
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Insights into the phosphoryl transfer catalyzed by cAMP-dependent protein kinase: an X-ray crystallographic study of complexes with various metals and peptide substrate SP20.
    Gerlits O; Waltman MJ; Taylor S; Langan P; Kovalevsky A
    Biochemistry; 2013 May; 52(21):3721-7. PubMed ID: 23672593
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The structural basis for seryl-adenylate and Ap4A synthesis by seryl-tRNA synthetase.
    Belrhali H; Yaremchuk A; Tukalo M; Berthet-Colominas C; Rasmussen B; Bösecke P; Diat O; Cusack S
    Structure; 1995 Apr; 3(4):341-52. PubMed ID: 7613865
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A novel deamido-NAD+-binding site revealed by the trapped NAD-adenylate intermediate in the NAD+ synthetase structure.
    Rizzi M; Bolognesi M; Coda A
    Structure; 1998 Sep; 6(9):1129-40. PubMed ID: 9753692
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structures of argininosuccinate synthetase in enzyme-ATP substrates and enzyme-AMP product forms: stereochemistry of the catalytic reaction.
    Goto M; Omi R; Miyahara I; Sugahara M; Hirotsu K
    J Biol Chem; 2003 Jun; 278(25):22964-71. PubMed ID: 12684518
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Crystal structure of D-stereospecific amidohydrolase from Streptomyces sp. 82F2 - insight into the structural factors for substrate specificity.
    Arima J; Shimone K; Miyatani K; Tsunehara Y; Isoda Y; Hino T; Nagano S
    FEBS J; 2016 Jan; 283(2):337-49. PubMed ID: 26513520
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mechanistic Insights from the Crystal Structure of Bacillus subtilis o-Succinylbenzoyl-CoA Synthetase Complexed with the Adenylate Intermediate.
    Chen Y; Jiang Y; Guo Z
    Biochemistry; 2016 Dec; 55(48):6685-6695. PubMed ID: 27933791
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mechanism of an ATP-dependent carboxylase, dethiobiotin synthetase, based on crystallographic studies of complexes with substrates and a reaction intermediate.
    Huang W; Jia J; Gibson KJ; Taylor WS; Rendina AR; Schneider G; Lindqvist Y
    Biochemistry; 1995 Sep; 34(35):10985-95. PubMed ID: 7669756
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Interconversion of ATP binding and conformational free energies by tryptophanyl-tRNA synthetase: structures of ATP bound to open and closed, pre-transition-state conformations.
    Retailleau P; Huang X; Yin Y; Hu M; Weinreb V; Vachette P; Vonrhein C; Bricogne G; Roversi P; Ilyin V; Carter CW
    J Mol Biol; 2003 Jan; 325(1):39-63. PubMed ID: 12473451
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Active site of lysyl-tRNA synthetase: structural studies of the adenylation reaction.
    Desogus G; Todone F; Brick P; Onesti S
    Biochemistry; 2000 Jul; 39(29):8418-25. PubMed ID: 10913247
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structures of prokaryotic ubiquitin-like protein Pup in complex with depupylase Dop reveal the mechanism of catalytic phosphate formation.
    Cui H; Müller AU; Leibundgut M; Tian J; Ban N; Weber-Ban E
    Nat Commun; 2021 Nov; 12(1):6635. PubMed ID: 34789727
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structural adaptation of an interacting non-native C-terminal helical extension revealed in the crystal structure of NAD+ synthetase from Bacillus anthracis.
    McDonald HM; Pruett PS; Deivanayagam C; Protasevich II; Carson WM; DeLucas LJ; Brouillette WJ; Brouillette CG
    Acta Crystallogr D Biol Crystallogr; 2007 Aug; 63(Pt 8):891-905. PubMed ID: 17642516
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Insights into cephamycin biosynthesis: the crystal structure of CmcI from Streptomyces clavuligerus.
    Oster LM; Lester DR; Terwisscha van Scheltinga A; Svenda M; van Lun M; Généreux C; Andersson I
    J Mol Biol; 2006 Apr; 358(2):546-58. PubMed ID: 16527306
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.