BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

177 related articles for article (PubMed ID: 12413472)

  • 1. Kinetics and inhibition of glutamate carboxypeptidase II using a microplate assay.
    Rojas C; Frazier ST; Flanary J; Slusher BS
    Anal Biochem; 2002 Nov; 310(1):50-4. PubMed ID: 12413472
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Binding of the glutamate carboxypeptidase II (NAALADase) inhibitor 2-PMPA to rat brain membranes.
    Tiffany CW; Cai NS; Rojas C; Slusher BS
    Eur J Pharmacol; 2001 Sep; 427(2):91-6. PubMed ID: 11557259
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Molecular modeling of the interactions of glutamate carboxypeptidase II with its potent NAAG-based inhibitors.
    Rong SB; Zhang J; Neale JH; Wroblewski JT; Wang S; Kozikowski AP
    J Med Chem; 2002 Sep; 45(19):4140-52. PubMed ID: 12213057
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Regulation of glutamate carboxypeptidase II hydrolysis of N-acetylaspartylglutamate (NAAG) in crayfish nervous tissue is mediated by glial glutamate and acetylcholine receptors.
    Urazaev AK; Grossfeld RM; Lieberman EM
    J Neurochem; 2005 May; 93(3):605-10. PubMed ID: 15836619
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Deletion of the glutamate carboxypeptidase II gene in mice reveals a second enzyme activity that hydrolyzes N-acetylaspartylglutamate.
    Bacich DJ; Ramadan E; O'Keefe DS; Bukhari N; Wegorzewska I; Ojeifo O; Olszewski R; Wrenn CC; Bzdega T; Wroblewska B; Heston WD; Neale JH
    J Neurochem; 2002 Oct; 83(1):20-9. PubMed ID: 12358725
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Glutamate carboxypeptidase II (GCPII) inhibitor 2-PMPA reduces rewarding effects of the synthetic cathinone MDPV in rats: a role for N-acetylaspartylglutamate (NAAG).
    Hicks C; Gregg RA; Nayak SU; Cannella LA; Schena GJ; Tallarida CS; Reitz AB; Smith GR; Rawls SM
    Psychopharmacology (Berl); 2017 Jun; 234(11):1671-1681. PubMed ID: 28251297
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Neuroprotection afforded by NAAG and NAALADase inhibition requires glial cells and metabotropic glutamate receptor activation.
    Thomas AG; Olkowski JL; Slusher BS
    Eur J Pharmacol; 2001 Aug; 426(1-2):35-8. PubMed ID: 11525768
    [TBL] [Abstract][Full Text] [Related]  

  • 8. N-acetyl-aspartyl-glutamate and inhibition of glutamate carboxypeptidases protects against soman-induced neuropathology.
    Guo H; Liu J; Van Shura K; Chen H; Flora MN; Myers TM; McDonough JH; McCabe JT
    Neurotoxicology; 2015 May; 48():180-91. PubMed ID: 25825357
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hydrolysis of the neuropeptide N-acetylaspartylglutamate (NAAG) by cloned human glutamate carboxypeptidase II.
    Luthi-Carter R; Barczak AK; Speno H; Coyle JT
    Brain Res; 1998 Jun; 795(1-2):341-8. PubMed ID: 9622670
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Selective inhibition of NAALADase, which converts NAAG to glutamate, reduces ischemic brain injury.
    Slusher BS; Vornov JJ; Thomas AG; Hurn PD; Harukuni I; Bhardwaj A; Traystman RJ; Robinson MB; Britton P; Lu XC; Tortella FC; Wozniak KM; Yudkoff M; Potter BM; Jackson PF
    Nat Med; 1999 Dec; 5(12):1396-402. PubMed ID: 10581082
    [TBL] [Abstract][Full Text] [Related]  

  • 11. N-acetylaspartylglutamate (NAAG) is the probable mediator of axon-to-glia signaling in the crayfish medial giant nerve fiber.
    Gafurov B; Urazaev AK; Grossfeld RM; Lieberman EM
    Neuroscience; 2001; 106(1):227-35. PubMed ID: 11564432
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Still NAAG'ing After All These Years: The Continuing Pursuit of GCPII Inhibitors.
    Vornov JJ; Hollinger KR; Jackson PF; Wozniak KM; Farah MH; Majer P; Rais R; Slusher BS
    Adv Pharmacol; 2016; 76():215-55. PubMed ID: 27288079
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Glutamate carboxypeptidase II is not an amyloid peptide-degrading enzyme.
    Alt J; Stathis M; Rojas C; Slusher B
    FASEB J; 2013 Jul; 27(7):2620-5. PubMed ID: 23525278
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structure-activity relationships of glutamate carboxypeptidase II (GCPII) inhibitors.
    Ferraris DV; Shukla K; Tsukamoto T
    Curr Med Chem; 2012; 19(9):1282-94. PubMed ID: 22304717
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Blockade of NAALADase: a novel neuroprotective strategy based on limiting glutamate and elevating NAAG.
    Vornov JJ; Wozniak K; Lu M; Jackson P; Tsukamoto T; Wang E; Slusher B
    Ann N Y Acad Sci; 1999; 890():400-5. PubMed ID: 10668445
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mechanisms for clearance of released N-acetylaspartylglutamate in crayfish nerve fibers: implications for axon-glia signaling.
    Urazaev AK; Buttram JG; Deen JP; Gafurov BS; Slusher BS; Grossfeld RM; Lieberman EM
    Neuroscience; 2001; 107(4):697-703. PubMed ID: 11720792
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design of NAALADase inhibitors: a novel neuroprotective strategy.
    Jackson PF; Slusher BS
    Curr Med Chem; 2001 Jul; 8(8):949-57. PubMed ID: 11375762
    [TBL] [Abstract][Full Text] [Related]  

  • 18. S1 pocket of glutamate carboxypeptidase II: a new binding site for amyloid-β degradation.
    Lee SK; Kim H; Cheong YH; Kim MJ; Jo SA; Youn HS; Park SI
    Biochem Biophys Res Commun; 2013 Sep; 438(4):765-71. PubMed ID: 23891752
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Glutamate carboxypeptidase II does not process amyloid-β peptide.
    Sedlák F; Šácha P; Blechová M; Březinová A; Šafařík M; Šebestík J; Konvalinka J
    FASEB J; 2013 Jul; 27(7):2626-32. PubMed ID: 23525279
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Expression of glutamate carboxypeptidase II in human brain.
    Sácha P; Zámecník J; Barinka C; Hlouchová K; Vícha A; Mlcochová P; Hilgert I; Eckschlager T; Konvalinka J
    Neuroscience; 2007 Feb; 144(4):1361-72. PubMed ID: 17150306
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.