BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

196 related articles for article (PubMed ID: 12414647)

  • 1. Loss of Brca2 and p53 synergistically promotes genomic instability and deregulation of T-cell apoptosis.
    Cheung AM; Hande MP; Jalali F; Tsao MS; Skinnider B; Hirao A; McPherson JP; Karaskova J; Suzuki A; Wakeham A; You-Ten A; Elia A; Squire J; Bristow R; Hakem R; Mak TW
    Cancer Res; 2002 Nov; 62(21):6194-204. PubMed ID: 12414647
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Defective T-cell receptor-induced apoptosis of T cells and rejection of transplanted immunogenic tumors in p53(-/-) mice.
    Singh N; Huang L; Qin H
    Eur J Immunol; 2010 Feb; 40(2):559-68. PubMed ID: 19950180
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of poly(ADP-ribose) polymerase activity accelerates T-cell lymphomagenesis in p53 deficient mice.
    Beneke R; Möröy T
    Oncogene; 2001 Dec; 20(56):8136-41. PubMed ID: 11781827
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Brca2 deficiency in the murine small intestine sensitizes to p53-dependent apoptosis and leads to the spontaneous deletion of stem cells.
    Hay T; Patrick T; Winton D; Sansom OJ; Clarke AR
    Oncogene; 2005 May; 24(23):3842-6. PubMed ID: 15735671
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Functional interplay of p53 and Mus81 in DNA damage responses and cancer.
    Pamidi A; Cardoso R; Hakem A; Matysiak-Zablocki E; Poonepalli A; Tamblyn L; Perez-Ordonez B; Hande MP; Sanchez O; Hakem R
    Cancer Res; 2007 Sep; 67(18):8527-35. PubMed ID: 17875692
    [TBL] [Abstract][Full Text] [Related]  

  • 6. DNA double-strand breaks, p53, and apoptosis during lymphomagenesis in scid/scid mice.
    Gurley KE; Vo K; Kemp CJ
    Cancer Res; 1998 Jul; 58(14):3111-5. PubMed ID: 9679979
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Thymic model for examining BRCA2 expression and function.
    Flores KG; McAllister KA; Greer PK; Wiseman RW; Hale LP
    Mol Carcinog; 2002 Nov; 35(3):103-9. PubMed ID: 12410562
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The CD2-scl transgene alters the phenotype and frequency of T-lymphomas in N-ras transgenic or p53 deficient mice.
    Curtis DJ; Robb L; Strasser A; Begley CG
    Oncogene; 1997 Dec; 15(24):2975-83. PubMed ID: 9416841
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cdt1 transgenic mice develop lymphoblastic lymphoma in the absence of p53.
    Seo J; Chung YS; Sharma GG; Moon E; Burack WR; Pandita TK; Choi K
    Oncogene; 2005 Dec; 24(55):8176-86. PubMed ID: 16261166
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Selection for loss of p53 function in T-cell lymphomagenesis is alleviated by Moloney murine leukemia virus infection in myc transgenic mice.
    Baxter EW; Blyth K; Cameron ER; Neil JC
    J Virol; 2001 Oct; 75(20):9790-8. PubMed ID: 11559812
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Block of T cell development in P53-deficient mice accelerates development of lymphomas with characteristic RAG-dependent cytogenetic alterations.
    Haines BB; Ryu CJ; Chang S; Protopopov A; Luch A; Kang YH; Draganov DD; Fragoso MF; Paik SG; Hong HJ; DePinho RA; Chen J
    Cancer Cell; 2006 Feb; 9(2):109-20. PubMed ID: 16473278
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A delayed chemically induced tumorigenesis in Brca2 mutant mice.
    Yan DH; Wen Y; Su LK; Xia W; Wang SC; Zhang S; Gan L; Lee DF; Spohn B; Frey JA; Hortobagyi GN; Hung MC
    Oncogene; 2004 Mar; 23(10):1896-901. PubMed ID: 14981540
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Lymphoma development in Bax transgenic mice is inhibited by Bcl-2 and associated with chromosomal instability.
    Luke JJ; Van De Wetering CI; Knudson CM
    Cell Death Differ; 2003 Jun; 10(6):740-8. PubMed ID: 12761582
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Apoptosis induced by gamma-irradiation, but not CD4 ligation, of peripheral T lymphocytes in vivo is p53-dependent.
    Malcomson RD; Clarke AR; Peter A; Coutts SB; Howie SE; Harrison DJ
    J Pathol; 1997 Feb; 181(2):166-71. PubMed ID: 9120720
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Reconstitution of wild-type p53 expression triggers apoptosis in a p53-negative v-myc retrovirus-induced T-cell lymphoma line.
    Wang Y; Ramqvist T; Szekely L; Axelson H; Klein G; Wiman KG
    Cell Growth Differ; 1993 Jun; 4(6):467-73. PubMed ID: 8373731
    [TBL] [Abstract][Full Text] [Related]  

  • 16. TCR-mediated death of mature T lymphocytes occurs in the absence of p53.
    Boehme SA; Lenardo MJ
    J Immunol; 1996 Jun; 156(11):4075-8. PubMed ID: 8666771
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The role of p53-mediated apoptosis as a crucial anti-tumor response to genomic instability: lessons from mouse models.
    Attardi LD
    Mutat Res; 2005 Jan; 569(1-2):145-57. PubMed ID: 15603759
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer.
    Jonkers J; Meuwissen R; van der Gulden H; Peterse H; van der Valk M; Berns A
    Nat Genet; 2001 Dec; 29(4):418-25. PubMed ID: 11694875
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cell cycle and genetic background dependence of the effect of loss of BRCA2 on ionizing radiation sensitivity.
    Tutt A; Connor F; Bertwistle D; Kerr P; Peacock J; Ross G; Ashworth A
    Oncogene; 2003 May; 22(19):2926-31. PubMed ID: 12771943
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mutations in the p53 and scid genes do not cooperate in lymphomagenesis in doubly heterozygous mice.
    Kosugi S; Miyazawa T; Chou D; Saito Y; Shinbo T; Matsuki A; Okano H; Miyaji C; Watanabe H; Hatakeyama K; Niwa O; Kominami R
    Biochem Biophys Res Commun; 1999 Feb; 255(1):99-103. PubMed ID: 10082662
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.