These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

124 related articles for article (PubMed ID: 12419015)

  • 1. Inhibition of zaleplon metabolism by cimetidine in the human liver: in vitro studies with subcellular fractions and precision-cut liver slices.
    Renwick AB; Ball SE; Tredger JM; Price RJ; Walters DG; Kao J; Scatina JA; Lake BG
    Xenobiotica; 2002 Oct; 32(10):849-62. PubMed ID: 12419015
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Metabolism of zaleplon by human liver: evidence for involvement of aldehyde oxidase.
    Lake BG; Ball SE; Kao J; Renwick AB; Price RJ; Scatina JA
    Xenobiotica; 2002 Oct; 32(10):835-47. PubMed ID: 12419014
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Metabolism of Zaleplon by human hepatic microsomal cytochrome P450 isoforms.
    Renwick AB; Mistry H; Ball SE; Walters DG; Kao J; Lake BG
    Xenobiotica; 1998 Apr; 28(4):337-48. PubMed ID: 9604298
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Variability of Zaleplon 5-Oxidase Activity in Mice and Humans, and Inhibition by Raloxifene.
    Tanoue C; Sugihara K; Tayama Y; Uramaru N; Watanabe Y; Ohta S; Kitamura S
    Drug Metab Lett; 2017; 10(4):278-285. PubMed ID: 28029084
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Prediction of human metabolism of the sedative-hypnotic zaleplon using chimeric mice transplanted with human hepatocytes.
    Tanoue C; Sugihara K; Uramaru N; Tayama Y; Watanabe Y; Horie T; Ohta S; Kitamura S
    Xenobiotica; 2013 Nov; 43(11):956-62. PubMed ID: 23651075
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Aldehyde oxidase-dependent marked species difference in hepatic metabolism of the sedative-hypnotic, zaleplon, between monkeys and rats.
    Kawashima K; Hosoi K; Naruke T; Shiba T; Kitamura M; Watabe T
    Drug Metab Dispos; 1999 Mar; 27(3):422-8. PubMed ID: 10064576
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Strain difference of oxidative metabolism of the sedative-hypnotic zaleplon by aldehyde oxidase and cytochrome P450 in vivo and in vitro in rats.
    Tanoue C; Sugihara K; Uramaru N; Watanabe Y; Tayama Y; Ohta S; Kitamura S
    Drug Metab Pharmacokinet; 2013; 28(3):269-73. PubMed ID: 23358259
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Metabolism of a novel phosphodiesterase-IV inhibitor (V11294) by human hepatic cytochrome P450 forms.
    Subrahmanyam V; Renwick AB; Walters DG; Price RJ; Tonelli AP; Lake BG
    Xenobiotica; 2002 Jun; 32(6):521-34. PubMed ID: 12160484
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hydralazine as a selective probe inactivator of aldehyde oxidase in human hepatocytes: estimation of the contribution of aldehyde oxidase to metabolic clearance.
    Strelevitz TJ; Orozco CC; Obach RS
    Drug Metab Dispos; 2012 Jul; 40(7):1441-8. PubMed ID: 22522748
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The in vitro hepatic metabolism of ABT-418, a cholinergic channel activator, in rats, dogs, cynomolgus monkeys, and humans.
    Rodrigues AD; Ferrero JL; Amann MT; Rotert GA; Cepa SP; Surber BW; Machinist JM; Tich NR; Sullivan JP; Garvey DS
    Drug Metab Dispos; 1994; 22(5):788-98. PubMed ID: 7530622
    [TBL] [Abstract][Full Text] [Related]  

  • 11. In vitro metabolism of terfenadine by a purified recombinant fusion protein containing cytochrome P4503A4 and NADPH-P450 reductase. Comparison to human liver microsomes and precision-cut liver tissue slices.
    Rodrigues AD; Mulford DJ; Lee RD; Surber BW; Kukulka MJ; Ferrero JL; Thomas SB; Shet MS; Estabrook RW
    Drug Metab Dispos; 1995 Jul; 23(7):765-75. PubMed ID: 7587966
    [TBL] [Abstract][Full Text] [Related]  

  • 12. In Vitro Inhibition of Human Aldehyde Oxidase Activity by Clinically Relevant Concentrations of Gefitinib and Erlotinib: Comparison with Select Metabolites, Molecular Docking Analysis, and Impact on Hepatic Metabolism of Zaleplon and Methotrexate.
    Tan WK; Tan ARY; Sivanandam P; Goh EJH; Yap ZP; Saburulla NF; Austin-Muttitt K; Mullins JGL; Lau AJ
    J Pharmacol Exp Ther; 2020 Aug; 374(2):295-307. PubMed ID: 32393528
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Zearanol metabolism by subcellular fractions from lamb liver.
    Pompa G; Montesissa C; Di Lauro FM; Fadini L; Capua C
    J Vet Pharmacol Ther; 1988 Jun; 11(2):197-203. PubMed ID: 3184259
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A study of the in vitro interaction between lidocaine and premedications using human liver microsomes.
    Nagashima A; Tanaka E; Inomata S; Honda K; Misawa S
    J Clin Pharm Ther; 2005 Apr; 30(2):185-8. PubMed ID: 15811173
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identification of cytochrome P-450 isoforms responsible for cis-tramadol metabolism in human liver microsomes.
    Subrahmanyam V; Renwick AB; Walters DG; Young PJ; Price RJ; Tonelli AP; Lake BG
    Drug Metab Dispos; 2001 Aug; 29(8):1146-55. PubMed ID: 11454734
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Metabolism of taxol by human and rat liver in vitro: a screen for drug interactions and interspecies differences.
    Jamis-Dow CA; Klecker RW; Katki AG; Collins JM
    Cancer Chemother Pharmacol; 1995; 36(2):107-14. PubMed ID: 7767945
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Metabolism of 2,5-bis(trifluoromethyl)-7-benzyloxy-4-trifluoromethylcoumarin by human hepatic CYP isoforms: evidence for selectivity towards CYP3A4.
    Renwick AB; Lewis DF; Fulford S; Surry D; Williams B; Worboys PD; Cai X; Wang RW; Price RJ; Lake BG; Evans DC
    Xenobiotica; 2001 Apr; 31(4):187-204. PubMed ID: 11465405
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Metabolism of 7-benzyloxy-4-trifluoromethyl-coumarin by human hepatic cytochrome P450 isoforms.
    Renwick AB; Surry D; Price RJ; Lake BG; Evans DC
    Xenobiotica; 2000 Oct; 30(10):955-69. PubMed ID: 11315104
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Catalyzation of cocaine N-demethylation by cytochromes P4502B, P4503A, and P4502D in fish liver.
    Arinç E; Bozcaarmutlu A
    J Biochem Mol Toxicol; 2003; 17(3):169-76. PubMed ID: 12815613
    [TBL] [Abstract][Full Text] [Related]  

  • 20. In vitro metabolism of tirilazad mesylate in male and female rats. Contribution of cytochrome P4502C11 and delta 4-5 alpha-reductase.
    Wienkers LC; Steenwyk RC; Mizsak SA; Pearson PG
    Drug Metab Dispos; 1995 Mar; 23(3):383-92. PubMed ID: 7628305
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.