These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
8. Synthesis and structure-activity relationships of 1-arylmethyl-5-aryl-6-methyluracils as potent gonadotropin-releasing hormone receptor antagonists. Guo Z; Zhu YF; Gross TD; Tucci FC; Gao Y; Moorjani M; Connors PJ; Rowbottom MW; Chen Y; Struthers RS; Xie Q; Saunders J; Reinhart G; Chen TK; Bonneville AL; Chen C J Med Chem; 2004 Feb; 47(5):1259-71. PubMed ID: 14971906 [TBL] [Abstract][Full Text] [Related]
9. Synthesis and structure-activity relationships of thieno[2,3-d]pyrimidine-2,4-dione derivatives as potent GnRH receptor antagonists. Guo Z; Chen Y; Wu D; Zhu YF; Struthers RS; Saunders J; Xie Q; Chen C Bioorg Med Chem Lett; 2003 Oct; 13(20):3617-22. PubMed ID: 14505682 [TBL] [Abstract][Full Text] [Related]
10. A new class of potent nonpeptide luteinizing hormone-releasing hormone (LHRH) antagonists: design and synthesis of 2-phenylimidazo[1,2-a]pyrimidin-5-ones. Sasaki S; Imaeda T; Hayase Y; Shimizu Y; Kasai S; Cho N; Harada M; Suzuki N; Furuya S; Fujino M Bioorg Med Chem Lett; 2002 Aug; 12(16):2073-7. PubMed ID: 12127507 [TBL] [Abstract][Full Text] [Related]
11. Efficient synthesis of bicyclic oxazolino- and thiazolino[3,2-c]pyrimidine-5,7-diones and its application to the synthesis of GnRH antagonists. Pontillo J; Chen C Bioorg Med Chem Lett; 2005 Mar; 15(5):1407-11. PubMed ID: 15713397 [TBL] [Abstract][Full Text] [Related]
12. Synthesis and structure-activity relationships of thieno[2,3-b]pyrroles as antagonists of the GnRH receptor. Arnould JC; Delouvrié B; Boutron P; Dossetter AG; Foote KM; Hamon A; Hancox U; Harris CS; Hutton M; Lamorlette M; Matusiak Z Bioorg Med Chem Lett; 2007 Dec; 17(23):6448-54. PubMed ID: 17937987 [TBL] [Abstract][Full Text] [Related]
13. The discovery of novel small molecule non-peptide gonadotropin releasing hormone (GnRH) receptor antagonists. Luthin DR; Hong Y; Pathak VP; Paderes G; Nared-Hood KD; Castro MA; Vazir H; Li H; Tompkins E; Christie L; May JM; Anderson MB Bioorg Med Chem Lett; 2002 Dec; 12(23):3467-70. PubMed ID: 12419385 [TBL] [Abstract][Full Text] [Related]
14. Synthesis and structure-activity relationships of 1-arylmethyl-3-(1-methyl-2-amino)ethyl-5-aryl-6-methyluracils as antagonists of the human GnRH Receptor. Tucci FC; Zhu YF; Guo Z; Gross TD; Connors PJ; Struthers RS; Reinhart GJ; Saunders J; Chen C Bioorg Med Chem Lett; 2003 Oct; 13(19):3317-22. PubMed ID: 12951117 [TBL] [Abstract][Full Text] [Related]
15. Dual inhibitors of thymidylate synthase and dihydrofolate reductase as antitumor agents: design, synthesis, and biological evaluation of classical and nonclassical pyrrolo[2,3-d]pyrimidine antifolates(1). Gangjee A; Jain HD; Phan J; Lin X; Song X; McGuire JJ; Kisliuk RL J Med Chem; 2006 Feb; 49(3):1055-65. PubMed ID: 16451071 [TBL] [Abstract][Full Text] [Related]
16. Discovery of a thieno[2,3-d]pyrimidine-2,4-dione bearing a p-methoxyureidophenyl moiety at the 6-position: a highly potent and orally bioavailable non-peptide antagonist for the human luteinizing hormone-releasing hormone receptor. Sasaki S; Cho N; Nara Y; Harada M; Endo S; Suzuki N; Furuya S; Fujino M J Med Chem; 2003 Jan; 46(1):113-24. PubMed ID: 12502365 [TBL] [Abstract][Full Text] [Related]
17. Synthesis and structure-activity relationships of 1-arylmethyl-3-(2-aminopropyl)-5-aryl-6-methyluracils as potent GnRH receptor antagonists. Guo Z; Zhu YF; Tucci FC; Gao Y; Struthers RS; Saunders J; Gross TD; Xie Q; Reinhart GJ; Chen C Bioorg Med Chem Lett; 2003 Oct; 13(19):3311-5. PubMed ID: 12951116 [TBL] [Abstract][Full Text] [Related]
18. 8-Aza-7,9-dideazaxanthine acyclic nucleoside phosphonate inhibitors of thymidine phosphorylase. Mařák D; Otmar M; Votruba I; Dračínský M; Krečmerová M Bioorg Med Chem Lett; 2011 Jan; 21(2):652-4. PubMed ID: 21195612 [TBL] [Abstract][Full Text] [Related]
19. Pyrrolo-pyrimidones: a novel class of MK2 inhibitors with potent cellular activity. Schlapbach A; Feifel R; Hawtin S; Heng R; Koch G; Moebitz H; Revesz L; Scheufler C; Velcicky J; Waelchli R; Huppertz C Bioorg Med Chem Lett; 2008 Dec; 18(23):6142-6. PubMed ID: 18945615 [TBL] [Abstract][Full Text] [Related]
20. Overlapping, nonidentical binding sites of different classes of nonpeptide antagonists for the human gonadotropin-releasing hormone receptor. Betz SF; Reinhart GJ; Lio FM; Chen C; Struthers RS J Med Chem; 2006 Jan; 49(2):637-47. PubMed ID: 16420049 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]