BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

386 related articles for article (PubMed ID: 12420214)

  • 1. Regulation of the IRF-1 tumour modifier during the response to genotoxic stress involves an ATM-dependent signalling pathway.
    Pamment J; Ramsay E; Kelleher M; Dornan D; Ball KL
    Oncogene; 2002 Nov; 21(51):7776-85. PubMed ID: 12420214
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cooperation of the tumour suppressors IRF-1 and p53 in response to DNA damage.
    Tanaka N; Ishihara M; Lamphier MS; Nozawa H; Matsuyama T; Mak TW; Aizawa S; Tokino T; Oren M; Taniguchi T
    Nature; 1996 Aug; 382(6594):816-8. PubMed ID: 8752276
    [TBL] [Abstract][Full Text] [Related]  

  • 3. ATM-dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the post-translational activation of p53 protein involving poly(ADP-ribose) polymerase.
    Vaziri H; West MD; Allsopp RC; Davison TS; Wu YS; Arrowsmith CH; Poirier GG; Benchimol S
    EMBO J; 1997 Oct; 16(19):6018-33. PubMed ID: 9312059
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Induction of ATF3 by ionizing radiation is mediated via a signaling pathway that includes ATM, Nibrin1, stress-induced MAPkinases and ATF-2.
    Kool J; Hamdi M; Cornelissen-Steijger P; van der Eb AJ; Terleth C; van Dam H
    Oncogene; 2003 Jul; 22(27):4235-42. PubMed ID: 12833146
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Arecoline-induced phosphorylated p53 and p21(WAF1) protein expression is dependent on ATM/ATR and phosphatidylinositol-3-kinase in clone-9 cells.
    Chou WW; Guh JY; Tsai JF; Hwang CC; Chiou SJ; Chuang LY
    J Cell Biochem; 2009 Jun; 107(3):408-17. PubMed ID: 19343784
    [TBL] [Abstract][Full Text] [Related]  

  • 6. DNA-dependent protein kinase is not required for accumulation of p53 or cell cycle arrest after DNA damage.
    Rathmell WK; Kaufmann WK; Hurt JC; Byrd LL; Chu G
    Cancer Res; 1997 Jan; 57(1):68-74. PubMed ID: 8988043
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Enhanced phosphorylation of p53 serine 18 following DNA damage in DNA-dependent protein kinase catalytic subunit-deficient cells.
    Araki R; Fukumura R; Fujimori A; Taya Y; Shiloh Y; Kurimasa A; Burma S; Li GC; Chen DJ; Sato K; Hoki Y; Tatsumi K; Abe M
    Cancer Res; 1999 Aug; 59(15):3543-6. PubMed ID: 10446957
    [TBL] [Abstract][Full Text] [Related]  

  • 8. ATM-dependent activation of p53 involves dephosphorylation and association with 14-3-3 proteins.
    Waterman MJ; Stavridi ES; Waterman JL; Halazonetis TD
    Nat Genet; 1998 Jun; 19(2):175-8. PubMed ID: 9620776
    [TBL] [Abstract][Full Text] [Related]  

  • 9. ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway.
    Lim DS; Kim ST; Xu B; Maser RS; Lin J; Petrini JH; Kastan MB
    Nature; 2000 Apr; 404(6778):613-7. PubMed ID: 10766245
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Role for ATM in DNA damage-induced phosphorylation of BRCA1.
    Gatei M; Scott SP; Filippovitch I; Soronika N; Lavin MF; Weber B; Khanna KK
    Cancer Res; 2000 Jun; 60(12):3299-304. PubMed ID: 10866324
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Chronic doxorubicin cardiotoxicity is mediated by oxidative DNA damage-ATM-p53-apoptosis pathway and attenuated by pitavastatin through the inhibition of Rac1 activity.
    Yoshida M; Shiojima I; Ikeda H; Komuro I
    J Mol Cell Cardiol; 2009 Nov; 47(5):698-705. PubMed ID: 19660469
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The isoflavonoids genistein and quercetin activate different stress signaling pathways as shown by analysis of site-specific phosphorylation of ATM, p53 and histone H2AX.
    Ye R; Goodarzi AA; Kurz EU; Saito S; Higashimoto Y; Lavin MF; Appella E; Anderson CW; Lees-Miller SP
    DNA Repair (Amst); 2004 Mar; 3(3):235-44. PubMed ID: 15177039
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Metabolic labeling of human cells with tritiated nucleosides results in activation of the ATM-dependent p53 signaling pathway and acceleration of DNA repair.
    Mirzayans R; Pollock S; Scott A; Gao CQ; Murray D
    Oncogene; 2003 Aug; 22(36):5562-71. PubMed ID: 12944903
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Arsenite induces p53 accumulation through an ATM-dependent pathway in human fibroblasts.
    Yih LH; Lee TC
    Cancer Res; 2000 Nov; 60(22):6346-52. PubMed ID: 11103796
    [TBL] [Abstract][Full Text] [Related]  

  • 15. E2F1 uses the ATM signaling pathway to induce p53 and Chk2 phosphorylation and apoptosis.
    Powers JT; Hong S; Mayhew CN; Rogers PM; Knudsen ES; Johnson DG
    Mol Cancer Res; 2004 Apr; 2(4):203-14. PubMed ID: 15140942
    [TBL] [Abstract][Full Text] [Related]  

  • 16. [Cell cycle regulation after exposure to ionizing radiation].
    Teyssier F; Bay JO; Dionet C; Verrelle P
    Bull Cancer; 1999 Apr; 86(4):345-57. PubMed ID: 10341340
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The role of the Ataxia telangiectasia gene in the p53, WAF1/CIP1(p21)- and GADD45-mediated response to DNA damage produced by ionising radiation.
    Artuso M; Esteve A; Brésil H; Vuillaume M; Hall J
    Oncogene; 1995 Oct; 11(8):1427-35. PubMed ID: 7478567
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Activation of multiple growth regulatory genes following inducible expression of IRF-1 or IRF/RelA fusion proteins.
    Nguyen H; Lin R; Hiscott J
    Oncogene; 1997 Sep; 15(12):1425-35. PubMed ID: 9333018
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Atm selectively regulates distinct p53-dependent cell-cycle checkpoint and apoptotic pathways.
    Barlow C; Brown KD; Deng CX; Tagle DA; Wynshaw-Boris A
    Nat Genet; 1997 Dec; 17(4):453-6. PubMed ID: 9398849
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cancer chemoprevention by the antioxidant tempol acts partially via the p53 tumor suppressor.
    Erker L; Schubert R; Yakushiji H; Barlow C; Larson D; Mitchell JB; Wynshaw-Boris A
    Hum Mol Genet; 2005 Jun; 14(12):1699-708. PubMed ID: 15888486
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.