These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

122 related articles for article (PubMed ID: 12420227)

  • 1. p16(INK4a) inactivation is not required to immortalize human mammary epithelial cells.
    Herbert BS; Wright WE; Shay JW
    Oncogene; 2002 Nov; 21(51):7897-900. PubMed ID: 12420227
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Comparison of human mammary epithelial cells immortalized by simian virus 40 T-Antigen or by the telomerase catalytic subunit.
    Toouli CD; Huschtscha LI; Neumann AA; Noble JR; Colgin LM; Hukku B; Reddel RR
    Oncogene; 2002 Jan; 21(1):128-39. PubMed ID: 11791183
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.
    Kiyono T; Foster SA; Koop JI; McDougall JK; Galloway DA; Klingelhutz AJ
    Nature; 1998 Nov; 396(6706):84-8. PubMed ID: 9817205
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Effects of simian virus 40 T-antigens on normal human mammary epithelial cells reveal evidence for spontaneous alterations in addition to loss of p16(INK4a) expression.
    Huschtscha LI; Neumann AA; Noble JR; Reddel RR
    Exp Cell Res; 2001 Apr; 265(1):125-34. PubMed ID: 11281650
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Events in the immortalizing process of primary human mammary epithelial cells by the catalytic subunit of human telomerase.
    Kim H; Farris J; Christman SA; Kong BW; Foster LK; O'Grady SM; Foster DN
    Biochem J; 2002 Aug; 365(Pt 3):765-72. PubMed ID: 11978176
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Prolonged culture of telomerase-immortalized human fibroblasts leads to a premalignant phenotype.
    Milyavsky M; Shats I; Erez N; Tang X; Senderovich S; Meerson A; Tabach Y; Goldfinger N; Ginsberg D; Harris CC; Rotter V
    Cancer Res; 2003 Nov; 63(21):7147-57. PubMed ID: 14612508
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Raf-1-induced growth arrest in human mammary epithelial cells is p16-independent and is overcome in immortal cells during conversion.
    Olsen CL; Gardie B; Yaswen P; Stampfer MR
    Oncogene; 2002 Sep; 21(41):6328-39. PubMed ID: 12214273
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The role of Ink4a/Arf in ErbB2 mammary gland tumorigenesis.
    D'Amico M; Wu K; Di Vizio D; Reutens AT; Stahl M; Fu M; Albanese C; Russell RG; Muller WJ; White M; Negassa A; Lee HW; DePinho RA; Pestell RG
    Cancer Res; 2003 Jun; 63(12):3395-402. PubMed ID: 12810676
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Telomerase induces immortalization of human esophageal keratinocytes without p16INK4a inactivation.
    Harada H; Nakagawa H; Oyama K; Takaoka M; Andl CD; Jacobmeier B; von Werder A; Enders GH; Opitz OG; Rustgi AK
    Mol Cancer Res; 2003 Aug; 1(10):729-38. PubMed ID: 12939398
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Keratinocyte growth conditions modulate telomerase expression, senescence, and immortalization by human papillomavirus type 16 E6 and E7 oncogenes.
    Fu B; Quintero J; Baker CC
    Cancer Res; 2003 Nov; 63(22):7815-24. PubMed ID: 14633708
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Increased p16 expression with first senescence arrest in human mammary epithelial cells and extended growth capacity with p16 inactivation.
    Brenner AJ; Stampfer MR; Aldaz CM
    Oncogene; 1998 Jul; 17(2):199-205. PubMed ID: 9674704
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Abrogation of the retinoblastoma tumor suppressor checkpoint during keratinocyte immortalization is not sufficient for induction of centrosome-mediated genomic instability.
    Piboonniyom SO; Duensing S; Swilling NW; Hasskarl J; Hinds PW; Münger K
    Cancer Res; 2003 Jan; 63(2):476-83. PubMed ID: 12543805
    [TBL] [Abstract][Full Text] [Related]  

  • 13. p16INK4a modulates p53 in primary human mammary epithelial cells.
    Zhang J; Pickering CR; Holst CR; Gauthier ML; Tlsty TD
    Cancer Res; 2006 Nov; 66(21):10325-31. PubMed ID: 17079452
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Senescence occurs with hTERT repression and limited telomere shortening in human oral keratinocytes cultured with feeder cells.
    Kang MK; Kameta A; Shin KH; Baluda MA; Park NH
    J Cell Physiol; 2004 Jun; 199(3):364-70. PubMed ID: 15095283
    [TBL] [Abstract][Full Text] [Related]  

  • 15. p57KIP2 expression and loss of heterozygosity during immortal conversion of cultured human mammary epithelial cells.
    Nijjar T; Wigington D; Garbe JC; Waha A; Stampfer MR; Yaswen P
    Cancer Res; 1999 Oct; 59(20):5112-8. PubMed ID: 10537284
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Disparate effects of telomere attrition on gene expression during replicative senescence of human mammary epithelial cells cultured under different conditions.
    Zhang H; Herbert BS; Pan KH; Shay JW; Cohen SN
    Oncogene; 2004 Aug; 23(37):6193-8. PubMed ID: 15195144
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Alterations in the p16(INK4a) and p53 tumor suppressor genes of hTERT-immortalized human fibroblasts.
    Noble JR; Zhong ZH; Neumann AA; Melki JR; Clark SJ; Reddel RR
    Oncogene; 2004 Apr; 23(17):3116-21. PubMed ID: 14743210
    [TBL] [Abstract][Full Text] [Related]  

  • 18. p16 INK4a can initiate an autonomous senescence program.
    Dai CY; Enders GH
    Oncogene; 2000 Mar; 19(13):1613-22. PubMed ID: 10763818
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Loss of p16INK4 expression by methylation is associated with lifespan extension of human mammary epithelial cells.
    Huschtscha LI; Noble JR; Neumann AA; Moy EL; Barry P; Melki JR; Clark SJ; Reddel RR
    Cancer Res; 1998 Aug; 58(16):3508-12. PubMed ID: 9721850
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Reduction in mortalin level by its antisense expression causes senescence-like growth arrest in human immortalized cells.
    Wadhwa R; Takano S; Taira K; Kaul SC
    J Gene Med; 2004 Apr; 6(4):439-44. PubMed ID: 15079818
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.