BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

175 related articles for article (PubMed ID: 12423170)

  • 1. Asymmetric synthesis of alpha,alpha-difluoro-beta-amino acid derivatives from enantiomerically pure N-tert-butylsulfinimines.
    Staas DD; Savage KL; Homnick CF; Tsou NN; Ball RG
    J Org Chem; 2002 Nov; 67(23):8276-9. PubMed ID: 12423170
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Convenient asymmetric synthesis of beta-substituted alpha,alpha-difluoro-beta-amino acids via Reformatsky reaction between Davis' N-sulfinylimines and ethyl bromodifluoroacetate.
    Sorochinsky A; Voloshin N; Markovsky A; Belik M; Yasuda N; Uekusa H; Ono T; Berbasov DO; Soloshonok VA
    J Org Chem; 2003 Sep; 68(19):7448-54. PubMed ID: 12968899
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Enantiopure trifluoromethylated β(3,3)-amino acids: synthesis by asymmetric Reformatsky reaction with stable analogues of trifluoromethyl N-tert-butanesulfinylketoimines and incorporation into α/β-peptides.
    Grellepois F
    J Org Chem; 2013 Feb; 78(3):1127-37. PubMed ID: 23273379
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Highly selective addition of chiral, sulfonimidoyl substituted bis(allyl)titanium complexes to N-sulfonyl alpha-imino esters: asymmetric synthesis of gamma,delta-unsaturated alpha-amino acids bearing a chiral, electron-withdrawing nucleofuge at the delta-position.
    Schleusner M; Gais HJ; Koep S; Raabe G
    J Am Chem Soc; 2002 Jul; 124(26):7789-800. PubMed ID: 12083933
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Preparation of Enantiomerically Pure Perfluorobutanesulfinamide and Its Application to the Asymmetric Synthesis of α-Amino Acids.
    Wangweerawong A; Hummel JR; Bergman RG; Ellman JA
    J Org Chem; 2016 Feb; 81(4):1547-57. PubMed ID: 26844947
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Efficient synthesis of enantiomerically pure beta2-amino acids via chiral isoxazolidinones.
    Lee HS; Park JS; Kim BM; Gellman SH
    J Org Chem; 2003 Feb; 68(4):1575-8. PubMed ID: 12585907
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Practical synthesis of fluorine-containing α- and β-amino acids: recipes from Kiev, Ukraine.
    Kukhar VP; Sorochinsky AE; Soloshonok VA
    Future Med Chem; 2009 Aug; 1(5):793-819. PubMed ID: 21426081
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Asymmetric synthesis of beta-amino acid derivatives incorporating a broad range of substitution patterns by enolate additions to tert-butanesulfinyl imines.
    Tang TP; Ellman JA
    J Org Chem; 2002 Nov; 67(22):7819-32. PubMed ID: 12398509
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Asymmetric synthesis of N-protected amino acids by the addition of organolithium carboxyl synthons to ROPHy/SOPHy-derived aldoximes and ketoximes.
    Cooper TS; Laurent P; Moody CJ; Takle AK
    Org Biomol Chem; 2004 Jan; 2(2):265-76. PubMed ID: 14737651
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Catalytic asymmetric Mannich reactions of glycine derivatives with imines. A new approach to optically active alpha,beta-diamino acid derivatives.
    Bernardi L; Gothelf AS; Hazell RG; Jørgensen KA
    J Org Chem; 2003 Apr; 68(7):2583-91. PubMed ID: 12662026
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Asymmetric synthesis of α-amino acids by reduction of N-tert-butanesulfinyl ketimine esters.
    Reddy LR; Gupta AP; Liu Y
    J Org Chem; 2011 May; 76(9):3409-15. PubMed ID: 21462993
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis of fluorinated chiral amines using N-tert-butylsulfinyl imines.
    Liu J; Hu J
    Future Med Chem; 2009 Aug; 1(5):875-88. PubMed ID: 21426086
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Asymmetric synthesis of protected α-amino boronic acid derivatives with an air- and moisture-stable Cu(II) catalyst.
    Buesking AW; Bacauanu V; Cai I; Ellman JA
    J Org Chem; 2014 Apr; 79(8):3671-7. PubMed ID: 24684495
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Lewis acid promoted highly diastereoselective Petasis Borono-Mannich reaction: efficient synthesis of optically active β,γ-unsaturated α-amino acids.
    Li Y; Xu MH
    Org Lett; 2012 Apr; 14(8):2062-5. PubMed ID: 22480132
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A diastereoselective Mannich-type reaction of α-fluorinated carboxylate esters: synthesis of β-amino acids containing α-quaternary fluorinated carbon centers.
    Li X; Li Y; Shang H
    Org Biomol Chem; 2016 Jul; 14(27):6457-62. PubMed ID: 27279124
    [TBL] [Abstract][Full Text] [Related]  

  • 16. An easy stereoselective access to beta,gamma-aziridino alpha-amino ester derivatives via mannich reaction of benzophenone imines of glycine esters with N-sulfonyl alpha-chloroaldimines.
    Kiss L; Mangelinckx S; Sillanpää R; Fülöp F; De Kimpe N
    J Org Chem; 2007 Sep; 72(19):7199-206. PubMed ID: 17705431
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis, structure, and biological applications of α-fluorinated β-amino acids and derivatives.
    March TL; Johnston MR; Duggan PJ; Gardiner J
    Chem Biodivers; 2012 Nov; 9(11):2410-41. PubMed ID: 23161626
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Expedient synthesis of threo-beta-hydroxy-alpha-amino acid derivatives: phenylalanine, tyrosine, histidine, and tryptophan.
    Crich D; Banerjee A
    J Org Chem; 2006 Sep; 71(18):7106-9. PubMed ID: 16930077
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Diastereoselective Addition of Metal α-Fluoroenolates of Carboxylate Esters to N-tert-Butylsulfinyl Imines: Synthesis of α-Fluoro-β-amino Acids.
    Shang H; Li Y; Li X; Ren X
    J Org Chem; 2015 Sep; 80(17):8739-47. PubMed ID: 26270259
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Enantioselective synthesis of fluorinated alpha-amino acids and derivatives in combination with ring-closing metathesis: intramolecular pi-stacking interactions as a source of stereocontrol.
    Fustero S; Navarro A; Pina B; Soler JG; Bartolomé A; Asensio A; Simón A; Bravo P; Fronza G; Volonterio A; Zanda M
    Org Lett; 2001 Aug; 3(17):2621-4. PubMed ID: 11506593
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.