150 related articles for article (PubMed ID: 12423235)
1. Increased CNS uptake and enhanced antinociception of morphine-6-glucuronide in rats after inhibition of P-glycoprotein.
Lötsch J; Schmidt R; Vetter G; Schmidt H; Niederberger E; Geisslinger G; Tegeder I
J Neurochem; 2002 Oct; 83(2):241-8. PubMed ID: 12423235
[TBL] [Abstract][Full Text] [Related]
2. The influence of inhibition of probenecid sensitive transporters on the central nervous system (CNS) uptake and the antinociceptive activity of morphine-6-glucuronide in rats.
Lötsch J; Schmidt R; Vetter G; Schmidt H; Skarke C; Niederberger E; Geisslinger G; Tegeder I
Neurosci Lett; 2002 Aug; 329(2):145-8. PubMed ID: 12165398
[TBL] [Abstract][Full Text] [Related]
3. Comparative measurement of spinal CSF microdialysate concentrations and concomitant antinociception of morphine and morphine-6beta-glucuronide in rats.
Okura T; Komiyama N; Morita Y; Kimura M; Deguchi Y; Yamada S
Life Sci; 2007 Mar; 80(14):1319-26. PubMed ID: 17258777
[TBL] [Abstract][Full Text] [Related]
4. Antinociceptive effects of morphine-6-glucuronide in homozygous MDR1a P-glycoprotein knockout and in wildtype mice in the hotplate test.
Lötsch J; Tegeder I; Angst MS; Geisslinger G
Life Sci; 2000 May; 66(24):2393-403. PubMed ID: 10864101
[TBL] [Abstract][Full Text] [Related]
5. Evidence for an active transport of morphine-6-beta-d-glucuronide but not P-glycoprotein-mediated at the blood-brain barrier.
Bourasset F; Cisternino S; Temsamani J; Scherrmann JM
J Neurochem; 2003 Sep; 86(6):1564-7. PubMed ID: 12950465
[TBL] [Abstract][Full Text] [Related]
6. Verapamil decreases glucuronidase activity in the gut.
Lötsch J; Sperker B; Kroemer HK; Geisslinger G
Biochem Pharmacol; 2002 Apr; 63(8):1575-8. PubMed ID: 11996900
[TBL] [Abstract][Full Text] [Related]
7. Blood-brain barrier transport and brain distribution of morphine-6-glucuronide in relation to the antinociceptive effect in rats--pharmacokinetic/pharmacodynamic modelling.
Bouw MR; Xie R; Tunblad K; Hammarlund-Udenaes M
Br J Pharmacol; 2001 Dec; 134(8):1796-804. PubMed ID: 11739257
[TBL] [Abstract][Full Text] [Related]
8. Concentration-effect relationships of morphine and morphine-6 beta-glucuronide in the rat.
van Crugten JT; Somogyi AA; Nation RL; Reynolds G
Clin Exp Pharmacol Physiol; 1997 May; 24(5):359-64. PubMed ID: 9143788
[TBL] [Abstract][Full Text] [Related]
9. Different distribution of morphine and morphine-6 beta-glucuronide after intracerebroventricular injection in rats.
Okura T; Saito M; Nakanishi M; Komiyama N; Fujii A; Yamada S; Kimura R
Br J Pharmacol; 2003 Sep; 140(1):211-7. PubMed ID: 12967951
[TBL] [Abstract][Full Text] [Related]
10. Different effects of morphine and morphine-6beta-glucuronide on formalin-evoked spinal glutamate release in conscious and freely moving rats.
Okura T; Komiyama N; Morita Y; Kimura M; Yamada S
Neurosci Lett; 2007 Mar; 415(2):169-73. PubMed ID: 17267124
[TBL] [Abstract][Full Text] [Related]
11. Apparent insensitivity of the hotplate latency test for detection of antinociception following intraperitoneal, intravenous or intracerebroventricular M6G administration to rats.
South SM; Smith MT
J Pharmacol Exp Ther; 1998 Sep; 286(3):1326-32. PubMed ID: 9732396
[TBL] [Abstract][Full Text] [Related]
12. Evidence that nitric oxide-glutamate cascade modulates spinal antinociceptive effect of morphine: a behavioural and microdialysis study in rats.
Watanabe C; Okuda K; Sakurada C; Ando R; Sakurada T; Sakurada S
Brain Res; 2003 Nov; 990(1-2):77-86. PubMed ID: 14568332
[TBL] [Abstract][Full Text] [Related]
13. Probenecid interacts with the pharmacokinetics of morphine-6-glucuronide in humans.
Skarke C; Langer M; Jarrar M; Schmidt H; Geisslinger G; Lötsch J
Anesthesiology; 2004 Dec; 101(6):1394-9. PubMed ID: 15564947
[TBL] [Abstract][Full Text] [Related]
14. The spinal antinociceptive actions of morphine metabolites morphine-6-glucuronide and normorphine in the rat.
Sullivan AF; McQuay HJ; Bailey D; Dickenson AH
Brain Res; 1989 Mar; 482(2):219-24. PubMed ID: 2706485
[TBL] [Abstract][Full Text] [Related]
15. Inhibition of noxious stimulus-induced spinal prostaglandin E2 release by flurbiprofen enantiomers: a microdialysis study.
Geisslinger G; Muth-Selbach U; Coste O; Vetter G; Schrödter A; Schaible HG; Brune K; Tegeder I
J Neurochem; 2000 May; 74(5):2094-100. PubMed ID: 10800954
[TBL] [Abstract][Full Text] [Related]
16. Pharmacokinetic-pharmacodynamic modeling of morphine-6-glucuronide-induced analgesia in healthy volunteers: absence of sex differences.
Romberg R; Olofsen E; Sarton E; den Hartigh J; Taschner PE; Dahan A
Anesthesiology; 2004 Jan; 100(1):120-33. PubMed ID: 14695733
[TBL] [Abstract][Full Text] [Related]
17. Impact of P-glycoprotein at the blood-brain barrier on the uptake of heroin and its main metabolites: behavioral effects and consequences on the transcriptional responses and reinforcing properties.
Seleman M; Chapy H; Cisternino S; Courtin C; Smirnova M; Schlatter J; Chiadmi F; Scherrmann JM; Noble F; Marie-Claire C
Psychopharmacology (Berl); 2014 Aug; 231(16):3139-49. PubMed ID: 24705903
[TBL] [Abstract][Full Text] [Related]
18. Carrier-mediated processes at several rat brain interfaces determine the neuropharmacokinetics of morphine and morphine-6-beta-D-glucuronide.
Bourasset F; Scherrmann JM
Life Sci; 2006 Apr; 78(20):2302-14. PubMed ID: 16309712
[TBL] [Abstract][Full Text] [Related]
19. Analgesic response and plasma and brain extracellular fluid pharmacokinetics of morphine and morphine-6-beta-D-glucuronide in the rat.
Stain F; Barjavel MJ; Sandouk P; Plotkine M; Scherrmann JM; Bhargava HN
J Pharmacol Exp Ther; 1995 Aug; 274(2):852-7. PubMed ID: 7636748
[TBL] [Abstract][Full Text] [Related]
20. P-glycoprotein modulates morphine uptake into the CNS: a role for the non-steroidal anti-inflammatory drug diclofenac.
Sanchez-Covarrubias L; Slosky LM; Thompson BJ; Zhang Y; Laracuente ML; DeMarco KM; Ronaldson PT; Davis TP
PLoS One; 2014; 9(2):e88516. PubMed ID: 24520393
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
