BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

351 related articles for article (PubMed ID: 12429067)

  • 21. The secretases of Alzheimer's disease.
    Wolfe MS
    Curr Top Dev Biol; 2003; 54():233-61. PubMed ID: 12696752
    [No Abstract]   [Full Text] [Related]  

  • 22. Closing in on the amyloid cascade: recent insights into the cell biology of Alzheimer's disease.
    Huse JT; Doms RW
    Mol Neurobiol; 2000; 22(1-3):81-98. PubMed ID: 11414282
    [TBL] [Abstract][Full Text] [Related]  

  • 23. The first proline of PALP motif at the C terminus of presenilins is obligatory for stabilization, complex formation, and gamma-secretase activities of presenilins.
    Tomita T; Watabiki T; Takikawa R; Morohashi Y; Takasugi N; Kopan R; De Strooper B; Iwatsubo T
    J Biol Chem; 2001 Aug; 276(35):33273-81. PubMed ID: 11432849
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Involvement of presenilins in cell-survival signalling pathways.
    McCarthy JV
    Biochem Soc Trans; 2005 Aug; 33(Pt 4):568-72. PubMed ID: 16042546
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Role of the proteasome in Alzheimer's disease.
    Checler F; da Costa CA; Ancolio K; Chevallier N; Lopez-Perez E; Marambaud P
    Biochim Biophys Acta; 2000 Jul; 1502(1):133-8. PubMed ID: 10899438
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Identification of the role of presenilins beyond Alzheimer's disease.
    Thinakaran G; Parent AT
    Pharmacol Res; 2004 Oct; 50(4):411-8. PubMed ID: 15304238
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Alzheimer's disease. Closing in on gamma-secretase.
    De Strooper B
    Nature; 2000 Jun; 405(6787):627, 629. PubMed ID: 10864307
    [No Abstract]   [Full Text] [Related]  

  • 28. RIPped out by presenilin-dependent gamma-secretase.
    Medina M; Dotti CG
    Cell Signal; 2003 Sep; 15(9):829-41. PubMed ID: 12834808
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Presenilin clinical mutations can affect gamma-secretase activity by different mechanisms.
    Bentahir M; Nyabi O; Verhamme J; Tolia A; Horré K; Wiltfang J; Esselmann H; De Strooper B
    J Neurochem; 2006 Feb; 96(3):732-42. PubMed ID: 16405513
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing.
    Yu G; Nishimura M; Arawaka S; Levitan D; Zhang L; Tandon A; Song YQ; Rogaeva E; Chen F; Kawarai T; Supala A; Levesque L; Yu H; Yang DS; Holmes E; Milman P; Liang Y; Zhang DM; Xu DH; Sato C; Rogaev E; Smith M; Janus C; Zhang Y; Aebersold R; Farrer LS; Sorbi S; Bruni A; Fraser P; St George-Hyslop P
    Nature; 2000 Sep; 407(6800):48-54. PubMed ID: 10993067
    [TBL] [Abstract][Full Text] [Related]  

  • 31. [Alzheimer's disease: focus on beta-amyloid and gamma-secretase].
    Iwatsubo T
    Tanpakushitsu Kakusan Koso; 2004 May; 49(7 Suppl):1086-90. PubMed ID: 15168534
    [No Abstract]   [Full Text] [Related]  

  • 32. Glycine 384 is required for presenilin-1 function and is conserved in bacterial polytopic aspartyl proteases.
    Steiner H; Kostka M; Romig H; Basset G; Pesold B; Hardy J; Capell A; Meyn L; Grim ML; Baumeister R; Fechteler K; Haass C
    Nat Cell Biol; 2000 Nov; 2(11):848-51. PubMed ID: 11056541
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Neuroscience. An accomplice for gamma-secretase brought into focus.
    Sisodia SS
    Science; 2000 Sep; 289(5488):2296-7. PubMed ID: 11041797
    [No Abstract]   [Full Text] [Related]  

  • 34. Total inactivation of gamma-secretase activity in presenilin-deficient embryonic stem cells.
    Herreman A; Serneels L; Annaert W; Collen D; Schoonjans L; De Strooper B
    Nat Cell Biol; 2000 Jul; 2(7):461-2. PubMed ID: 10878813
    [No Abstract]   [Full Text] [Related]  

  • 35. Implication of APP secretases in notch signaling.
    Hartmann D; Tournoy J; Saftig P; Annaert W; De Strooper B
    J Mol Neurosci; 2001 Oct; 17(2):171-81. PubMed ID: 11816790
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Conserved "PAL" sequence in presenilins is essential for gamma-secretase activity, but not required for formation or stabilization of gamma-secretase complexes.
    Wang J; Brunkan AL; Hecimovic S; Walker E; Goate A
    Neurobiol Dis; 2004 Apr; 15(3):654-66. PubMed ID: 15056474
    [TBL] [Abstract][Full Text] [Related]  

  • 37. BACE1: the beta-secretase enzyme in Alzheimer's disease.
    Vassar R
    J Mol Neurosci; 2004; 23(1-2):105-14. PubMed ID: 15126696
    [TBL] [Abstract][Full Text] [Related]  

  • 38. gamma-Secretase activity requires the presenilin-dependent trafficking of nicastrin through the Golgi apparatus but not its complex glycosylation.
    Herreman A; Van Gassen G; Bentahir M; Nyabi O; Craessaerts K; Mueller U; Annaert W; De Strooper B
    J Cell Sci; 2003 Mar; 116(Pt 6):1127-36. PubMed ID: 12584255
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Proteolysis by presenilins and the renaissance of tau.
    Haass C; Mandelkow E
    Trends Cell Biol; 1999 Jun; 9(6):241-4. PubMed ID: 10408925
    [No Abstract]   [Full Text] [Related]  

  • 40. Presenilin, Notch, and the genesis and treatment of Alzheimer's disease.
    Selkoe DJ
    Proc Natl Acad Sci U S A; 2001 Sep; 98(20):11039-41. PubMed ID: 11572965
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 18.