These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

350 related articles for article (PubMed ID: 12429520)

  • 21. Lentiviral Nef proteins manipulate T cells in a subset-specific manner.
    Yu H; Khalid M; Heigele A; Schmökel J; Usmani SM; van der Merwe J; Münch J; Silvestri G; Kirchhoff F
    J Virol; 2015 Feb; 89(4):1986-2001. PubMed ID: 25505066
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Mechanism of Nef-induced CD4 endocytosis: Nef connects CD4 with the mu chain of adaptor complexes.
    Piguet V; Chen YL; Mangasarian A; Foti M; Carpentier JL; Trono D
    EMBO J; 1998 May; 17(9):2472-81. PubMed ID: 9564030
    [TBL] [Abstract][Full Text] [Related]  

  • 23. A conserved domain and membrane targeting of Nef from HIV and SIV are required for association with a cellular serine kinase activity.
    Sawai ET; Baur AS; Peterlin BM; Levy JA; Cheng-Mayer C
    J Biol Chem; 1995 Jun; 270(25):15307-14. PubMed ID: 7797518
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Differential interaction of the CD2 extracellular and intracellular domains with the tyrosine phosphatase CD45 and the zeta chain of the TCR/CD3/zeta complex.
    Verhagen AM; Schraven B; Wild M; Wallich R; Meuer SC
    Eur J Immunol; 1996 Dec; 26(12):2841-9. PubMed ID: 8977276
    [TBL] [Abstract][Full Text] [Related]  

  • 25. A dileucine motif in HIV-1 Nef acts as an internalization signal for CD4 downregulation and binds the AP-1 clathrin adaptor.
    Bresnahan PA; Yonemoto W; Ferrell S; Williams-Herman D; Geleziunas R; Greene WC
    Curr Biol; 1998 Nov; 8(22):1235-8. PubMed ID: 9811606
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Co-localization of HIV-1 Nef with the AP-2 adaptor protein complex correlates with Nef-induced CD4 down-regulation.
    Greenberg ME; Bronson S; Lock M; Neumann M; Pavlakis GN; Skowronski J
    EMBO J; 1997 Dec; 16(23):6964-76. PubMed ID: 9384576
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Specific suppression of human CD4 surface expression by Nef from the pathogenic simian immunodeficiency virus SIVmac239open.
    Foster JL; Anderson SJ; Frazier AL; Garcia JV
    Virology; 1994 Jun; 201(2):373-9. PubMed ID: 8184546
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Loss of Nef-mediated CD3 down-regulation in the HIV-1 lineage increases viral infectivity and spread.
    Mesner D; Hotter D; Kirchhoff F; Jolly C
    Proc Natl Acad Sci U S A; 2020 Mar; 117(13):7382-7391. PubMed ID: 32179688
    [TBL] [Abstract][Full Text] [Related]  

  • 29. The SH3 domain-binding surface and an acidic motif in HIV-1 Nef regulate trafficking of class I MHC complexes.
    Greenberg ME; Iafrate AJ; Skowronski J
    EMBO J; 1998 May; 17(10):2777-89. PubMed ID: 9582271
    [TBL] [Abstract][Full Text] [Related]  

  • 30. CD4 and MHC-I downregulation are conserved in primary HIV-1 Nef alleles from brain and lymphoid tissues, but Pak2 activation is highly variable.
    Agopian K; Wei BL; Garcia JV; Gabuzda D
    Virology; 2007 Feb; 358(1):119-35. PubMed ID: 16979207
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Nef-Mediated CD3-TCR Downmodulation Dampens Acute Inflammation and Promotes SIV Immune Evasion.
    Joas S; Sauermann U; Roshani B; Klippert A; Daskalaki M; Mätz-Rensing K; Stolte-Leeb N; Heigele A; Tharp GK; Gupta PM; Nelson S; Bosinger S; Parodi L; Giavedoni L; Silvestri G; Sauter D; Stahl-Hennig C; Kirchhoff F
    Cell Rep; 2020 Feb; 30(7):2261-2274.e7. PubMed ID: 32075764
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Cutting edge: SIV Nef protein utilizes both leucine- and tyrosine-based protein sorting pathways for down-regulation of CD4.
    Bresnahan PA; Yonemoto W; Greene WC
    J Immunol; 1999 Sep; 163(6):2977-81. PubMed ID: 10477559
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Down-modulation of mature major histocompatibility complex class II and up-regulation of invariant chain cell surface expression are well-conserved functions of human and simian immunodeficiency virus nef alleles.
    Schindler M; Würfl S; Benaroch P; Greenough TC; Daniels R; Easterbrook P; Brenner M; Münch J; Kirchhoff F
    J Virol; 2003 Oct; 77(19):10548-56. PubMed ID: 12970439
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Primary sooty mangabey simian immunodeficiency virus and human immunodeficiency virus type 2 nef alleles modulate cell surface expression of various human receptors and enhance viral infectivity and replication.
    Münch J; Schindler M; Wildum S; Rücker E; Bailer N; Knoop V; Novembre FJ; Kirchhoff F
    J Virol; 2005 Aug; 79(16):10547-60. PubMed ID: 16051847
    [TBL] [Abstract][Full Text] [Related]  

  • 35. SIVcol Nef counteracts SERINC5 by promoting its proteasomal degradation but does not efficiently enhance HIV-1 replication in human CD4+ T cells and lymphoid tissue.
    Kmiec D; Akbil B; Ananth S; Hotter D; Sparrer KMJ; Stürzel CM; Trautz B; Ayouba A; Peeters M; Yao Z; Stagljar I; Passos V; Zillinger T; Goffinet C; Sauter D; Fackler OT; Kirchhoff F
    PLoS Pathog; 2018 Aug; 14(8):e1007269. PubMed ID: 30125328
    [TBL] [Abstract][Full Text] [Related]  

  • 36. The Nef protein of human immunodeficiency virus is a broad-spectrum modulator of chemokine receptor cell surface levels that acts independently of classical motifs for receptor endocytosis and Galphai signaling.
    Michel N; Ganter K; Venzke S; Bitzegeio J; Fackler OT; Keppler OT
    Mol Biol Cell; 2006 Aug; 17(8):3578-90. PubMed ID: 16775006
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Simian immunodeficiency virus and human immunodeficiency virus type 1 nef proteins show distinct patterns and mechanisms of Src kinase activation.
    Greenway AL; Dutartre H; Allen K; McPhee DA; Olive D; Collette Y
    J Virol; 1999 Jul; 73(7):6152-8. PubMed ID: 10364375
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Primate lentiviral Nef proteins deregulate T-cell development by multiple mechanisms.
    Van Nuffel A; Ariën KK; Stove V; Schindler M; O'Neill E; Schmökel J; Van de Walle I; Naessens E; Vanderstraeten H; Van Landeghem K; Taghon T; Pulkkinen K; Saksela K; Garcia JV; Fackler OT; Kirchhoff F; Verhasselt B
    Retrovirology; 2013 Nov; 10():137. PubMed ID: 24237970
    [TBL] [Abstract][Full Text] [Related]  

  • 39. HIV-2 and SIV nef proteins target different Src family SH3 domains than does HIV-1 Nef because of a triple amino acid substitution.
    Collette Y; Arold S; Picard C; Janvier K; Benichou S; Benarous R; Olive D; Dumas C
    J Biol Chem; 2000 Feb; 275(6):4171-6. PubMed ID: 10660579
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Myristoylation-dependent binding of HIV-1 Nef to CD4.
    Harris MP; Neil JC
    J Mol Biol; 1994 Aug; 241(2):136-42. PubMed ID: 8057354
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 18.