1273 related articles for article (PubMed ID: 12429646)
1. Antitumor activity of UCN-01 in carcinomas of the head and neck is associated with altered expression of cyclin D3 and p27(KIP1).
Patel V; Lahusen T; Leethanakul C; Igishi T; Kremer M; Quintanilla-Martinez L; Ensley JF; Sausville EA; Gutkind JS; Senderowicz AM
Clin Cancer Res; 2002 Nov; 8(11):3549-60. PubMed ID: 12429646
[TBL] [Abstract][Full Text] [Related]
2. G1 phase accumulation induced by UCN-01 is associated with dephosphorylation of Rb and CDK2 proteins as well as induction of CDK inhibitor p21/Cip1/WAF1/Sdi1 in p53-mutated human epidermoid carcinoma A431 cells.
Akiyama T; Yoshida T; Tsujita T; Shimizu M; Mizukami T; Okabe M; Akinaga S
Cancer Res; 1997 Apr; 57(8):1495-501. PubMed ID: 9108451
[TBL] [Abstract][Full Text] [Related]
3. Critical role of both p27KIP1 and p21CIP1/WAF1 in the antiproliferative effect of ZD1839 ('Iressa'), an epidermal growth factor receptor tyrosine kinase inhibitor, in head and neck squamous carcinoma cells.
Di Gennaro E; Barbarino M; Bruzzese F; De Lorenzo S; Caraglia M; Abbruzzese A; Avallone A; Comella P; Caponigro F; Pepe S; Budillon A
J Cell Physiol; 2003 Apr; 195(1):139-50. PubMed ID: 12599217
[TBL] [Abstract][Full Text] [Related]
4. Flavopiridol, a novel cyclin-dependent kinase inhibitor, suppresses the growth of head and neck squamous cell carcinomas by inducing apoptosis.
Patel V; Senderowicz AM; Pinto D; Igishi T; Raffeld M; Quintanilla-Martinez L; Ensley JF; Sausville EA; Gutkind JS
J Clin Invest; 1998 Nov; 102(9):1674-81. PubMed ID: 9802881
[TBL] [Abstract][Full Text] [Related]
5. Decrease in susceptibility toward induction of apoptosis and alteration in G1 checkpoint function as determinants of resistance of human lung cancer cells against the antisignaling drug UCN-01 (7-Hydroxystaurosporine).
Sugiyama K; Akiyama T; Shimizu M; Tamaoki T; Courage C; Gescher A; Akinaga S
Cancer Res; 1999 Sep; 59(17):4406-12. PubMed ID: 10485490
[TBL] [Abstract][Full Text] [Related]
6. Lovastatin mediated G1 arrest in normal and tumor breast cells is through inhibition of CDK2 activity and redistribution of p21 and p27, independent of p53.
Rao S; Lowe M; Herliczek TW; Keyomarsi K
Oncogene; 1998 Nov; 17(18):2393-402. PubMed ID: 9811471
[TBL] [Abstract][Full Text] [Related]
7. Ketoconazole potentiates the antitumor effects of nocodazole: In vivo therapy for human tumor xenografts in nude mice.
Wang YJ; Jeng JH; Chen RJ; Tseng H; Chen LC; Liang YC; Lin CH; Chen CH; Chu JS; Ho WL; Ho YS
Mol Carcinog; 2002 Aug; 34(4):199-210. PubMed ID: 12203371
[TBL] [Abstract][Full Text] [Related]
8. Inhibition of the melanoma cell cycle and regulation at the G1/S transition by 12-O-tetradecanoylphorbol-13-acetate (TPA) by modulation of CDK2 activity.
Coppock DL; Buffolino P; Kopman C; Nathanson L
Exp Cell Res; 1995 Nov; 221(1):92-102. PubMed ID: 7589260
[TBL] [Abstract][Full Text] [Related]
9. Activation of cdk4 and cdk2 during rat liver regeneration is associated with intranuclear rearrangements of cyclin-cdk complexes.
Jaumot M; Estanyol JM; Serratosa J; Agell N; Bachs O
Hepatology; 1999 Feb; 29(2):385-95. PubMed ID: 9918914
[TBL] [Abstract][Full Text] [Related]
10. Retinoic acid-mediated growth arrest of EBV-immortalized B lymphocytes is associated with multiple changes in G1 regulatory proteins: p27Kip1 up-regulation is a relevant early event.
Zancai P; Cariati R; Rizzo S; Boiocchi M; Dolcetti R
Oncogene; 1998 Oct; 17(14):1827-36. PubMed ID: 9778049
[TBL] [Abstract][Full Text] [Related]
11. UCN-01-induced cell cycle arrest requires the transcriptional induction of p21(waf1/cip1) by activation of mitogen-activated protein/extracellular signal-regulated kinase kinase/extracellular signal-regulated kinase pathway.
Facchinetti MM; De Siervi A; Toskos D; Senderowicz AM
Cancer Res; 2004 May; 64(10):3629-37. PubMed ID: 15150122
[TBL] [Abstract][Full Text] [Related]
12. Retinoic acid-mediated G1 arrest is associated with induction of p27(Kip1) and inhibition of cyclin-dependent kinase 3 in human lung squamous carcinoma CH27 cells.
Hsu SL; Hsu JW; Liu MC; Chen LY; Chang CD
Exp Cell Res; 2000 Aug; 258(2):322-31. PubMed ID: 10896783
[TBL] [Abstract][Full Text] [Related]
13. BMP-7-induced cell cycle arrest of anaplastic thyroid carcinoma cells via p21(CIP1) and p27(KIP1).
Franzén A ; Heldin NE
Biochem Biophys Res Commun; 2001 Jul; 285(3):773-81. PubMed ID: 11453659
[TBL] [Abstract][Full Text] [Related]
14. BCL-x(L) and BCL2 delay Myc-induced cell cycle entry through elevation of p27 and inhibition of G1 cyclin-dependent kinases.
Greider C; Chattopadhyay A; Parkhurst C; Yang E
Oncogene; 2002 Nov; 21(51):7765-75. PubMed ID: 12420213
[TBL] [Abstract][Full Text] [Related]
15. G1-checkpoint function including a cyclin-dependent kinase 2 regulatory pathway as potential determinant of 7-hydroxystaurosporine (UCN-01)-induced apoptosis and G1-phase accumulation.
Akiyama T; Sugiyama K; Shimizu M; Tamaoki T; Akinaga S
Jpn J Cancer Res; 1999 Dec; 90(12):1364-72. PubMed ID: 10665655
[TBL] [Abstract][Full Text] [Related]
16. Differential control of cyclins D1 and D3 and the cdk inhibitor p27Kip1 by diverse signalling pathways in Swiss 3T3 cells.
Mann DJ; Higgins T; Jones NC; Rozengurt E
Oncogene; 1997 Apr; 14(15):1759-66. PubMed ID: 9150381
[TBL] [Abstract][Full Text] [Related]
17. UCN-01-mediated G1 arrest in normal but not tumor breast cells is pRb-dependent and p53-independent.
Chen X; Lowe M; Keyomarsi K
Oncogene; 1999 Oct; 18(41):5691-702. PubMed ID: 10577141
[TBL] [Abstract][Full Text] [Related]
18. Lactoferrin inhibits G1 cyclin-dependent kinases during growth arrest of human breast carcinoma cells.
Damiens E; El Yazidi I; Mazurier J; Duthille I; Spik G; Boilly-Marer Y
J Cell Biochem; 1999 Sep; 74(3):486-98. PubMed ID: 10412049
[TBL] [Abstract][Full Text] [Related]
19. Evidence for a p23 caspase-cleaved form of p27[KIP1] involved in G1 growth arrest.
Loubat A; Rochet N; Turchi L; Rezzonico R; Far DF; Auberger P; Rossi B; Ponzio G
Oncogene; 1999 Jun; 18(22):3324-33. PubMed ID: 10362353
[TBL] [Abstract][Full Text] [Related]
20. UCN-01 (7-hydoxystaurosporine) inhibits in vivo growth of human cancer cells through selective perturbation of G1 phase checkpoint machinery.
Abe S; Kubota T; Otani Y; Furukawa T; Watanabe M; Kumai K; Akiyama T; Akinaga S; Kitajima M
Jpn J Cancer Res; 2001 May; 92(5):537-45. PubMed ID: 11376563
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
