BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

451 related articles for article (PubMed ID: 12429923)

  • 1. The cancer preventive flavonoid silibinin causes hypophosphorylation of Rb/p107 and Rb2/p130 via modulation of cell cycle regulators in human prostate carcinoma DU145 cells.
    Tyagi A; Agarwal C; Agarwal R
    Cell Cycle; 2002; 1(2):137-42. PubMed ID: 12429923
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of retinoblastoma protein (Rb) phosphorylation at serine sites and an increase in Rb-E2F complex formation by silibinin in androgen-dependent human prostate carcinoma LNCaP cells: role in prostate cancer prevention.
    Tyagi A; Agarwal C; Agarwal R
    Mol Cancer Ther; 2002 May; 1(7):525-32. PubMed ID: 12479270
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Molecular mechanisms underlying interferon-alpha-induced G0/G1 arrest: CKI-mediated regulation of G1 Cdk-complexes and activation of pocket proteins.
    Sangfelt O; Erickson S; Castro J; Heiden T; Gustafsson A; Einhorn S; Grandér D
    Oncogene; 1999 May; 18(18):2798-810. PubMed ID: 10362250
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Differential responses of skin cancer-chemopreventive agents silibinin, quercetin, and epigallocatechin 3-gallate on mitogenic signaling and cell cycle regulators in human epidermoid carcinoma A431 cells.
    Bhatia N; Agarwal C; Agarwal R
    Nutr Cancer; 2001; 39(2):292-9. PubMed ID: 11759294
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Expression and activity of the retinoblastoma protein (pRB)-family proteins, p107 and p130, during L6 myoblast differentiation.
    Kiess M; Gill RM; Hamel PA
    Cell Growth Differ; 1995 Oct; 6(10):1287-98. PubMed ID: 8845306
    [TBL] [Abstract][Full Text] [Related]  

  • 6. c-Myc regulates cyclin D-Cdk4 and -Cdk6 activity but affects cell cycle progression at multiple independent points.
    Mateyak MK; Obaya AJ; Sedivy JM
    Mol Cell Biol; 1999 Jul; 19(7):4672-83. PubMed ID: 10373516
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inositol hexaphosphate inhibits growth, and induces G1 arrest and apoptotic death of prostate carcinoma DU145 cells: modulation of CDKI-CDK-cyclin and pRb-related protein-E2F complexes.
    Singh RP; Agarwal C; Agarwal R
    Carcinogenesis; 2003 Mar; 24(3):555-63. PubMed ID: 12663518
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Lycopene inhibition of cell cycle progression in breast and endometrial cancer cells is associated with reduction in cyclin D levels and retention of p27(Kip1) in the cyclin E-cdk2 complexes.
    Nahum A; Hirsch K; Danilenko M; Watts CK; Prall OW; Levy J; Sharoni Y
    Oncogene; 2001 Jun; 20(26):3428-36. PubMed ID: 11423993
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The E2F-family proteins induce distinct cell cycle regulatory factors in p16-arrested, U343 astrocytoma cells.
    Dirks PB; Rutka JT; Hubbard SL; Mondal S; Hamel PA
    Oncogene; 1998 Aug; 17(7):867-76. PubMed ID: 9780003
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cdk2-dependent phosphorylation and functional inactivation of the pRB-related p130 protein in pRB(-), p16INK4A(+) tumor cells.
    Cheng L; Rossi F; Fang W; Mori T; Cobrinik D
    J Biol Chem; 2000 Sep; 275(39):30317-25. PubMed ID: 10906146
    [TBL] [Abstract][Full Text] [Related]  

  • 11. E2F/p107 and E2F/p130 complexes are regulated by C/EBPalpha in 3T3-L1 adipocytes.
    Timchenko NA; Wilde M; Iakova P; Albrecht JH; Darlington GJ
    Nucleic Acids Res; 1999 Sep; 27(17):3621-30. PubMed ID: 10446255
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A pure estrogen antagonist inhibits cyclin E-Cdk2 activity in MCF-7 breast cancer cells and induces accumulation of p130-E2F4 complexes characteristic of quiescence.
    Carroll JS; Prall OW; Musgrove EA; Sutherland RL
    J Biol Chem; 2000 Dec; 275(49):38221-9. PubMed ID: 10991938
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Rapamycin potentiates transforming growth factor beta-induced growth arrest in nontransformed, oncogene-transformed, and human cancer cells.
    Law BK; Chytil A; Dumont N; Hamilton EG; Waltner-Law ME; Aakre ME; Covington C; Moses HL
    Mol Cell Biol; 2002 Dec; 22(23):8184-98. PubMed ID: 12417722
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Disruption of the actin cytoskeleton leads to inhibition of mitogen-induced cyclin E expression, Cdk2 phosphorylation, and nuclear accumulation of the retinoblastoma protein-related p107 protein.
    Reshetnikova G; Barkan R; Popov B; Nikolsky N; Chang LS
    Exp Cell Res; 2000 Aug; 259(1):35-53. PubMed ID: 10942577
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Glucocorticoids inhibit developmental stage-specific osteoblast cell cycle. Dissociation of cyclin A-cyclin-dependent kinase 2 from E2F4-p130 complexes.
    Smith E; Redman RA; Logg CR; Coetzee GA; Kasahara N; Frenkel B
    J Biol Chem; 2000 Jun; 275(26):19992-20001. PubMed ID: 10867026
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Tangeretin induces cell-cycle G1 arrest through inhibiting cyclin-dependent kinases 2 and 4 activities as well as elevating Cdk inhibitors p21 and p27 in human colorectal carcinoma cells.
    Pan MH; Chen WJ; Lin-Shiau SY; Ho CT; Lin JK
    Carcinogenesis; 2002 Oct; 23(10):1677-84. PubMed ID: 12376477
    [TBL] [Abstract][Full Text] [Related]  

  • 17. TGF-beta-mediated cell cycle arrest of HPV16-immortalized human ectocervical cells correlates with decreased E6/E7 mRNA and increased p53 and p21(WAF-1) expression.
    Rorke EA; Zhang D; Choo CK; Eckert RL; Jacobberger JW
    Exp Cell Res; 2000 Aug; 259(1):149-57. PubMed ID: 10942587
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Induction of cyclins E and A in response to mitogen removal: a basic alteration associated with the arrest of differentiation of C2 myoblasts transformed by simian virus 40 large T antigen.
    Tedesco D; Baron L; Fischer-Fantuzzi L; Vesco C
    J Virol; 1997 Mar; 71(3):2217-24. PubMed ID: 9032356
    [TBL] [Abstract][Full Text] [Related]  

  • 19. BMP-7-induced cell cycle arrest of anaplastic thyroid carcinoma cells via p21(CIP1) and p27(KIP1).
    Franzén A ; Heldin NE
    Biochem Biophys Res Commun; 2001 Jul; 285(3):773-81. PubMed ID: 11453659
    [TBL] [Abstract][Full Text] [Related]  

  • 20. p130 and p107 use a conserved domain to inhibit cellular cyclin-dependent kinase activity.
    Woo MS; Sánchez I; Dynlacht BD
    Mol Cell Biol; 1997 Jul; 17(7):3566-79. PubMed ID: 9199292
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.