159 related articles for article (PubMed ID: 12429974)
1. Enhancement of activation-induced apoptosis of lymphocytes by the cytotoxic ribonuclease onconase (Ranpirnase).
Halicka DH; Pozarowski P; Ita M; Ardelt WJ; Mikulski SM; Shogen K; Darzynkiewicz Z
Int J Oncol; 2002 Dec; 21(6):1245-50. PubMed ID: 12429974
[TBL] [Abstract][Full Text] [Related]
2. Induction of differentiation of leukaemic (HL-60) or prostate cancer (LNCaP, JCA-1) cells potentiates apoptosis triggered by onconase.
Halicka HD; Murakami T; Papageorgio CN; Mittelman A; Mikulski SM; Shogen K; Darzynkiewicz Z
Cell Prolif; 2000 Dec; 33(6):407-17. PubMed ID: 11101012
[TBL] [Abstract][Full Text] [Related]
3. Activation of caspases and serine proteases during apoptosis induced by onconase (Ranpirnase).
Grabarek J; Ardelt B; Du L; Darzynkiewicz Z
Exp Cell Res; 2002 Aug; 278(1):61-71. PubMed ID: 12126958
[TBL] [Abstract][Full Text] [Related]
4. Cytostatic and cytotoxic properties of Amphinase: a novel cytotoxic ribonuclease from Rana pipiens oocytes.
Ardelt B; Ardelt W; Pozarowski P; Kunicki J; Shogen K; Darzynkiewicz Z
Cell Cycle; 2007 Dec; 6(24):3097-102. PubMed ID: 18073526
[TBL] [Abstract][Full Text] [Related]
5. Treatment of Jurkat acute T-lymphocytic leukemia cells by onconase (Ranpirnase) is accompanied by an altered nucleocytoplasmic distribution and reduced expression of transcription factor NF-kappaB.
Tsai SY; Ardelt B; Hsieh TC; Darzynkiewicz Z; Shogen K; Wu JM
Int J Oncol; 2004 Dec; 25(6):1745-52. PubMed ID: 15547713
[TBL] [Abstract][Full Text] [Related]
6. Synergism between a novel amphibian oocyte ribonuclease and lovastatin in inducing cytostatic and cytotoxic effects in human lung and pancreatic carcinoma cell lines.
Mikulski SM; Viera A; Darzynkiewicz Z; Shogen K
Br J Cancer; 1992 Aug; 66(2):304-10. PubMed ID: 1503903
[TBL] [Abstract][Full Text] [Related]
7. Bovine seminal ribonuclease induces in vitro concentration dependent apoptosis in stimulated human lymphocytes and cells from human tumor cell lines.
Marinov I; Soucek J
Neoplasma; 2000; 47(5):294-8. PubMed ID: 11130246
[TBL] [Abstract][Full Text] [Related]
8. Onconase and amphinase, the antitumor ribonucleases from Rana pipiens oocytes.
Ardelt W; Shogen K; Darzynkiewicz Z
Curr Pharm Biotechnol; 2008 Jun; 9(3):215-25. PubMed ID: 18673287
[TBL] [Abstract][Full Text] [Related]
9. Mechanisms of enhanced tumoricidal efficacy of multiple small dosages of ranpirnase, the novel cytotoxic ribonuclease, on lung cancer.
Lee I; Shogen K
Cancer Chemother Pharmacol; 2008 Jul; 62(2):337-46. PubMed ID: 18064463
[TBL] [Abstract][Full Text] [Related]
10. The interdependence between catalytic activity, conformational stability, and cytotoxicity of onconase.
Schulenburg C; Ardelt B; Ardelt W; Arnold U; Shogen K; Ulbrich-Hofmann R; Darzynkiewicz Z
Cancer Biol Ther; 2007 Aug; 6(8):1233-9. PubMed ID: 17637563
[TBL] [Abstract][Full Text] [Related]
11. Enhancement of vincristine cytotoxicity in drug-resistant cells by simultaneous treatment with onconase, an antitumor ribonuclease.
Rybak SM; Pearson JW; Fogler WE; Volker K; Spence SE; Newton DL; Mikulski SM; Ardelt W; Riggs CW; Kung HF; Longo DL
J Natl Cancer Inst; 1996 Jun; 88(11):747-53. PubMed ID: 8637029
[TBL] [Abstract][Full Text] [Related]
12. A human ribonuclease induces apoptosis associated with p21WAF1/CIP1 induction and JNK inactivation.
Castro J; Ribó M; Navarro S; Nogués MV; Vilanova M; Benito A
BMC Cancer; 2011 Jan; 11():9. PubMed ID: 21223552
[TBL] [Abstract][Full Text] [Related]
13. Ribonucleases as potential modalities in anticancer therapy.
Ardelt W; Ardelt B; Darzynkiewicz Z
Eur J Pharmacol; 2009 Dec; 625(1-3):181-9. PubMed ID: 19825371
[TBL] [Abstract][Full Text] [Related]
14. Onconase dimerization through 3D domain swapping: structural investigations and increase in the apoptotic effect in cancer cells.
Fagagnini A; Pica A; Fasoli S; Montioli R; Donadelli M; Cordani M; Butturini E; Acquasaliente L; Picone D; Gotte G
Biochem J; 2017 Nov; 474(22):3767-3781. PubMed ID: 28963346
[TBL] [Abstract][Full Text] [Related]
15. Potentiation of tumor necrosis factor induced apoptosis by onconase.
Deptala A; Halicka HD; Ardelt B; Ardelt W; Mikulski SM; Shogen K; Darzynkiewicz Z
Int J Oncol; 1998 Jul; 13(1):11-6. PubMed ID: 9625797
[TBL] [Abstract][Full Text] [Related]
16. Onconase induces autophagy sensitizing pancreatic cancer cells to gemcitabine and activates Akt/mTOR pathway in a ROS-dependent manner.
Fiorini C; Cordani M; Gotte G; Picone D; Donadelli M
Biochim Biophys Acta; 2015 Mar; 1853(3):549-60. PubMed ID: 25533084
[TBL] [Abstract][Full Text] [Related]
17. Effect of camptothecin on mitogenic stimulation of human lymphocytes: involvement of DNA topoisomerase I in cell transition from G0 to G1 phase of the cell cycle and in DNA replication.
Bruno S; Giaretti W; Darzynkiewicz Z
J Cell Physiol; 1992 Jun; 151(3):478-86. PubMed ID: 1338332
[TBL] [Abstract][Full Text] [Related]
18. Effects of genistein on the growth and cell cycle progression of normal human lymphocytes and human leukemic MOLT-4 and HL-60 cells.
Traganos F; Ardelt B; Halko N; Bruno S; Darzynkiewicz Z
Cancer Res; 1992 Nov; 52(22):6200-8. PubMed ID: 1330289
[TBL] [Abstract][Full Text] [Related]
19. Human mesothelioma cells exhibit tumor cell-specific differences in phosphatidylinositol 3-kinase/AKT activity that predict the efficacy of Onconase.
Ramos-Nino ME; Vianale G; Sabo-Attwood T; Mutti L; Porta C; Heintz N; Mossman BT
Mol Cancer Ther; 2005 May; 4(5):835-42. PubMed ID: 15897248
[TBL] [Abstract][Full Text] [Related]
20. Molecular determinants of apoptosis induced by the cytotoxic ribonuclease onconase: evidence for cytotoxic mechanisms different from inhibition of protein synthesis.
Iordanov MS; Ryabinina OP; Wong J; Dinh TH; Newton DL; Rybak SM; Magun BE
Cancer Res; 2000 Apr; 60(7):1983-94. PubMed ID: 10766189
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]