These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

286 related articles for article (PubMed ID: 12432923)

  • 1. Mammalian arachidonate 15-lipoxygenases structure, function, and biological implications.
    Kuhn H; Walther M; Kuban RJ
    Prostaglandins Other Lipid Mediat; 2002 Aug; 68-69():263-90. PubMed ID: 12432923
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Alterations of lipoxygenase specificity by targeted substrate modification and site-directed mutagenesis.
    Walther M; Ivanov I; Myagkova G; Kuhn H
    Chem Biol; 2001 Aug; 8(8):779-90. PubMed ID: 11514227
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The N-terminal β-barrel domain of mammalian lipoxygenases including mouse 5-lipoxygenase is not essential for catalytic activity and membrane binding but exhibits regulatory functions.
    Walther M; Hofheinz K; Vogel R; Roffeis J; Kühn H
    Arch Biochem Biophys; 2011 Dec; 516(1):1-9. PubMed ID: 21951814
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Exploration of binding site pattern in arachidonic acid metabolizing enzymes, Cyclooxygenases and Lipoxygenases.
    Reddy KK; Vidya Rajan VK; Gupta A; Aparoy P; Reddanna P
    BMC Res Notes; 2015 Apr; 8():152. PubMed ID: 25886468
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of amino acid determinants of the positional specificity of mouse 8S-lipoxygenase and human 15S-lipoxygenase-2.
    Jisaka M; Kim RB; Boeglin WE; Brash AR
    J Biol Chem; 2000 Jan; 275(2):1287-93. PubMed ID: 10625675
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The role of lipoxygenases in pathophysiology; new insights and future perspectives.
    Mashima R; Okuyama T
    Redox Biol; 2015 Dec; 6():297-310. PubMed ID: 26298204
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural basis for lipoxygenase specificity. Conversion of the human leukocyte 5-lipoxygenase to a 15-lipoxygenating enzyme species by site-directed mutagenesis.
    Schwarz K; Walther M; Anton M; Gerth C; Feussner I; Kuhn H
    J Biol Chem; 2001 Jan; 276(1):773-9. PubMed ID: 11027682
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The role of lipoxygenase-isoforms in atherogenesis.
    Kühn H; Römisch I; Belkner J
    Mol Nutr Food Res; 2005 Nov; 49(11):1014-29. PubMed ID: 16270276
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Understanding the Mechanism of the Hydrogen Abstraction from Arachidonic Acid Catalyzed by the Human Enzyme 15-Lipoxygenase-2. A Quantum Mechanics/Molecular Mechanics Free Energy Simulation.
    Suardíaz R; Jambrina PG; Masgrau L; González-Lafont À; Rosta E; Lluch JM
    J Chem Theory Comput; 2016 Apr; 12(4):2079-90. PubMed ID: 26918937
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mammalian lipoxygenases and their biological relevance.
    Kuhn H; Banthiya S; van Leyen K
    Biochim Biophys Acta; 2015 Apr; 1851(4):308-30. PubMed ID: 25316652
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Molecular enzymology of lipoxygenases.
    Ivanov I; Heydeck D; Hofheinz K; Roffeis J; O'Donnell VB; Kuhn H; Walther M
    Arch Biochem Biophys; 2010 Nov; 503(2):161-74. PubMed ID: 20801095
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural and functional biology of arachidonic acid 15-lipoxygenase-1 (ALOX15).
    Ivanov I; Kuhn H; Heydeck D
    Gene; 2015 Nov; 573(1):1-32. PubMed ID: 26216303
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Phenylalanine 353 is a primary determinant for the positional specificity of mammalian 15-lipoxygenases.
    Borngräber S; Kuban RJ; Anton M; Kühn H
    J Mol Biol; 1996 Dec; 264(5):1145-53. PubMed ID: 9000636
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Probing conformational changes in lipoxygenases upon membrane binding: fine-tuning by the active site inhibitor ETYA.
    Di Venere A; Nicolai E; Ivanov I; Dainese E; Adel S; Angelucci BC; Kuhn H; Maccarrone M; Mei G
    Biochim Biophys Acta; 2014 Jan; 1841(1):1-10. PubMed ID: 24012824
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Arachidonate 15-lipoxygenase of reticulocyte-type in human rheumatoid arthritis type B synoviocytes and modulation of its activity by proinflammatory cytokines.
    Liagre B; Vergne P; Rigaud M; Beneytout JL
    J Rheumatol; 1999 May; 26(5):1044-51. PubMed ID: 10332966
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Molecular basis for the catalytic inactivity of a naturally occurring near-null variant of human ALOX15.
    Horn T; Ivanov I; Di Venere A; Kakularam KR; Reddanna P; Conrad ML; Richter C; Scheerer P; Kuhn H
    Biochim Biophys Acta; 2013 Dec; 1831(12):1702-13. PubMed ID: 23958500
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Emerging cellular functions of the lipid metabolizing enzyme 15-Lipoxygenase-1.
    Çolakoğlu M; Tunçer S; Banerjee S
    Cell Prolif; 2018 Oct; 51(5):e12472. PubMed ID: 30062726
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ligand-induced formation of transient dimers of mammalian 12/15-lipoxygenase: a key to allosteric behavior of this class of enzymes?
    Ivanov I; Shang W; Toledo L; Masgrau L; Svergun DI; Stehling S; Gómez H; Di Venere A; Mei G; Lluch JM; Skrzypczak-Jankun E; González-Lafont A; Kühn H
    Proteins; 2012 Mar; 80(3):703-12. PubMed ID: 22189720
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Biologic relevance of lipoxygenase isoforms in atherogenesis.
    Kuhn H
    Expert Rev Cardiovasc Ther; 2005 Nov; 3(6):1099-110. PubMed ID: 16293000
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Tight association of N-terminal and catalytic subunits of rabbit 12/15-lipoxygenase is important for protein stability and catalytic activity.
    Ivanov I; Di Venere A; Horn T; Scheerer P; Nicolai E; Stehling S; Richter C; Skrzypczak-Jankun E; Mei G; Maccarrone M; Kühn H
    Biochim Biophys Acta; 2011 Dec; 1811(12):1001-10. PubMed ID: 21875687
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.