328 related articles for article (PubMed ID: 12438278)
1. Mutant epidermal growth factor receptor signaling down-regulates p27 through activation of the phosphatidylinositol 3-kinase/Akt pathway in glioblastomas.
Narita Y; Nagane M; Mishima K; Huang HJ; Furnari FB; Cavenee WK
Cancer Res; 2002 Nov; 62(22):6764-9. PubMed ID: 12438278
[TBL] [Abstract][Full Text] [Related]
2. A common mutant epidermal growth factor receptor confers enhanced tumorigenicity on human glioblastoma cells by increasing proliferation and reducing apoptosis.
Nagane M; Coufal F; Lin H; Bögler O; Cavenee WK; Huang HJ
Cancer Res; 1996 Nov; 56(21):5079-86. PubMed ID: 8895767
[TBL] [Abstract][Full Text] [Related]
3. ErbB2/neu kinase modulates cellular p27(Kip1) and cyclin D1 through multiple signaling pathways.
Lenferink AE; Busse D; Flanagan WM; Yakes FM; Arteaga CL
Cancer Res; 2001 Sep; 61(17):6583-91. PubMed ID: 11522658
[TBL] [Abstract][Full Text] [Related]
4. EGF-dependent cell cycle progression is controlled by density-dependent regulation of Akt activation.
LeVea CM; Reeder JE; Mooney RA
Exp Cell Res; 2004 Jul; 297(1):272-84. PubMed ID: 15194442
[TBL] [Abstract][Full Text] [Related]
5. The phosphoinositide 3-kinase/Akt pathway regulates cell cycle progression of HL60 human leukemia cells through cytoplasmic relocalization of the cyclin-dependent kinase inhibitor p27(Kip1) and control of cyclin D1 expression.
Cappellini A; Tabellini G; Zweyer M; Bortul R; Tazzari PL; Billi AM; Falà F; Cocco L; Martelli AM
Leukemia; 2003 Nov; 17(11):2157-67. PubMed ID: 12931221
[TBL] [Abstract][Full Text] [Related]
6. Herceptin-induced inhibition of phosphatidylinositol-3 kinase and Akt Is required for antibody-mediated effects on p27, cyclin D1, and antitumor action.
Yakes FM; Chinratanalab W; Ritter CA; King W; Seelig S; Arteaga CL
Cancer Res; 2002 Jul; 62(14):4132-41. PubMed ID: 12124352
[TBL] [Abstract][Full Text] [Related]
7. EGF stimulates mesangial cell mitogenesis via PI3-kinase-mediated MAPK-dependent and AKT kinase-independent manner: involvement of c-fos and p27Kip1.
Mahimainathan L; Ghosh-Choudhury N; Venkatesan BA; Danda RS; Choudhury GG
Am J Physiol Renal Physiol; 2005 Jul; 289(1):F72-82. PubMed ID: 15701816
[TBL] [Abstract][Full Text] [Related]
8. The tyrosine phosphatase SHP-2 is required for mediating phosphatidylinositol 3-kinase/Akt activation by growth factors.
Wu CJ; O'Rourke DM; Feng GS; Johnson GR; Wang Q; Greene MI
Oncogene; 2001 Sep; 20(42):6018-25. PubMed ID: 11593409
[TBL] [Abstract][Full Text] [Related]
9. Herstatin, an autoinhibitor of the epidermal growth factor receptor family, blocks the intracranial growth of glioblastoma.
Staverosky JA; Muldoon LL; Guo S; Evans AJ; Neuwelt EA; Clinton GM
Clin Cancer Res; 2005 Jan; 11(1):335-40. PubMed ID: 15671564
[TBL] [Abstract][Full Text] [Related]
10. BCR signals target p27(Kip1) and cyclin D2 via the PI3-K signalling pathway to mediate cell cycle arrest and apoptosis of WEHI 231 B cells.
Banerji L; Glassford J; Lea NC; Thomas NS; Klaus GG; Lam EW
Oncogene; 2001 Nov; 20(50):7352-67. PubMed ID: 11704865
[TBL] [Abstract][Full Text] [Related]
11. Growth suppression of intracranial xenografted glioblastomas overexpressing mutant epidermal growth factor receptors by systemic administration of monoclonal antibody (mAb) 806, a novel monoclonal antibody directed to the receptor.
Mishima K; Johns TG; Luwor RB; Scott AM; Stockert E; Jungbluth AA; Ji XD; Suvarna P; Voland JR; Old LJ; Huang HJ; Cavenee WK
Cancer Res; 2001 Jul; 61(14):5349-54. PubMed ID: 11454673
[TBL] [Abstract][Full Text] [Related]
12. Inhibition of EGFR-mediated phosphoinositide-3-OH kinase (PI3-K) signaling and glioblastoma phenotype by signal-regulatory proteins (SIRPs).
Wu CJ; Chen Z; Ullrich A; Greene MI; O'Rourke DM
Oncogene; 2000 Aug; 19(35):3999-4010. PubMed ID: 10962556
[TBL] [Abstract][Full Text] [Related]
13. PKB/Akt phosphorylates p27, impairs nuclear import of p27 and opposes p27-mediated G1 arrest.
Liang J; Zubovitz J; Petrocelli T; Kotchetkov R; Connor MK; Han K; Lee JH; Ciarallo S; Catzavelos C; Beniston R; Franssen E; Slingerland JM
Nat Med; 2002 Oct; 8(10):1153-60. PubMed ID: 12244302
[TBL] [Abstract][Full Text] [Related]
14. Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer.
Viglietto G; Motti ML; Bruni P; Melillo RM; D'Alessio A; Califano D; Vinci F; Chiappetta G; Tsichlis P; Bellacosa A; Fusco A; Santoro M
Nat Med; 2002 Oct; 8(10):1136-44. PubMed ID: 12244303
[TBL] [Abstract][Full Text] [Related]
15. The epidermal growth factor receptor pathway mediates resistance to sequential administration of radiation and chemotherapy in primary human glioblastoma cells in a RAS-dependent manner.
Chakravarti A; Chakladar A; Delaney MA; Latham DE; Loeffler JS
Cancer Res; 2002 Aug; 62(15):4307-15. PubMed ID: 12154034
[TBL] [Abstract][Full Text] [Related]
16. Bradykinin-induced p42/p44 MAPK phosphorylation and cell proliferation via Src, EGF receptors, and PI3-K/Akt in vascular smooth muscle cells.
Yang CM; Lin MI; Hsieh HL; Sun CC; Ma YH; Hsiao LD
J Cell Physiol; 2005 Jun; 203(3):538-46. PubMed ID: 15573401
[TBL] [Abstract][Full Text] [Related]
17. Differential regulation of phosphatidylinositol 3-kinase/Akt, mitogen-activated protein kinase, and AMP-activated protein kinase pathways during menadione-induced oxidative stress in the kidney of young and old rats.
Jin Q; Jhun BS; Lee SH; Lee J; Pi Y; Cho YH; Baik HH; Kang I
Biochem Biophys Res Commun; 2004 Mar; 315(3):555-61. PubMed ID: 14975736
[TBL] [Abstract][Full Text] [Related]
18. Disruption of cooperation between Ras and MycN in human neuroblastoma cells promotes growth arrest.
Yaari S; Jacob-Hirsch J; Amariglio N; Haklai R; Rechavi G; Kloog Y
Clin Cancer Res; 2005 Jun; 11(12):4321-30. PubMed ID: 15958613
[TBL] [Abstract][Full Text] [Related]
19. P27 expression is regulated by separate signaling pathways, downstream of Ras, in each cell cycle phase.
Sa G; Stacey DW
Exp Cell Res; 2004 Nov; 300(2):427-39. PubMed ID: 15475007
[TBL] [Abstract][Full Text] [Related]
20. Adenoviral-mediated expression of a kinase-dead mutant of Akt induces apoptosis selectively in tumor cells and suppresses tumor growth in mice.
Jetzt A; Howe JA; Horn MT; Maxwell E; Yin Z; Johnson D; Kumar CC
Cancer Res; 2003 Oct; 63(20):6697-706. PubMed ID: 14583464
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]