These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

135 related articles for article (PubMed ID: 12438316)

  • 1. Location of the pteroylpolyglutamate-binding site on rabbit cytosolic serine hydroxymethyltransferase.
    Fu TF; Scarsdale JN; Kazanina G; Schirch V; Wright HT
    J Biol Chem; 2003 Jan; 278(4):2645-53. PubMed ID: 12438316
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Role of Lys-226 in the catalytic mechanism of Bacillus stearothermophilus serine hydroxymethyltransferase--crystal structure and kinetic studies.
    Bhavani S; Trivedi V; Jala VR; Subramanya HS; Kaul P; Prakash V; Appaji Rao N; Savithri HS
    Biochemistry; 2005 May; 44(18):6929-37. PubMed ID: 15865438
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Crystal structure at 2.4 A resolution of E. coli serine hydroxymethyltransferase in complex with glycine substrate and 5-formyl tetrahydrofolate.
    Scarsdale JN; Radaev S; Kazanina G; Schirch V; Wright HT
    J Mol Biol; 2000 Feb; 296(1):155-68. PubMed ID: 10656824
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure determination and biochemical studies on Bacillus stearothermophilus E53Q serine hydroxymethyltransferase and its complexes provide insights on function and enzyme memory.
    Rajaram V; Bhavani BS; Kaul P; Prakash V; Appaji Rao N; Savithri HS; Murthy MR
    FEBS J; 2007 Aug; 274(16):4148-60. PubMed ID: 17651438
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The role of His-134, -147, and -150 residues in subunit assembly, cofactor binding, and catalysis of sheep liver cytosolic serine hydroxymethyltransferase.
    Jagath JR; Sharma B; Rao NA; Savithri HS
    J Biol Chem; 1997 Sep; 272(39):24355-62. PubMed ID: 9305893
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Properties of human and rabbit cytosolic serine hydroxymethyltransferase are changed by single nucleotide polymorphic mutations.
    Fu TF; Hunt S; Schirch V; Safo MK; Chen BH
    Arch Biochem Biophys; 2005 Oct; 442(1):92-101. PubMed ID: 16137637
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Crystal structure of rabbit cytosolic serine hydroxymethyltransferase at 2.8 A resolution: mechanistic implications.
    Scarsdale JN; Kazanina G; Radaev S; Schirch V; Wright HT
    Biochemistry; 1999 Jun; 38(26):8347-58. PubMed ID: 10387080
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structure of a murine cytoplasmic serine hydroxymethyltransferase quinonoid ternary complex: evidence for asymmetric obligate dimers.
    Szebenyi DM; Liu X; Kriksunov IA; Stover PJ; Thiel DJ
    Biochemistry; 2000 Nov; 39(44):13313-23. PubMed ID: 11063567
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structure-based mechanism for early PLP-mediated steps of rabbit cytosolic serine hydroxymethyltransferase reaction.
    Di Salvo ML; Scarsdale JN; Kazanina G; Contestabile R; Schirch V; Wright HT
    Biomed Res Int; 2013; 2013():458571. PubMed ID: 23956983
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Serine hydroxymethyltransferase: role of glu75 and evidence that serine is cleaved by a retroaldol mechanism.
    Szebenyi DM; Musayev FN; di Salvo ML; Safo MK; Schirch V
    Biochemistry; 2004 Jun; 43(22):6865-76. PubMed ID: 15170323
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Disruption of distal interactions of Arg 262 and of substrate binding to Ser 52 affect catalysis of sheep liver cytosolic serine hydroxymethyltransferase.
    Jala VR; Ambili M; Prakash V; Rao NA; Savithri HS
    Indian J Biochem Biophys; 2003 Aug; 40(4):226-37. PubMed ID: 22900314
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The crystal structure of human cytosolic serine hydroxymethyltransferase: a target for cancer chemotherapy.
    Renwick SB; Snell K; Baumann U
    Structure; 1998 Sep; 6(9):1105-16. PubMed ID: 9753690
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification of amino acid residues, essential for maintaining the tetrameric structure of sheep liver cytosolic serine hydroxymethyltransferase, by targeted mutagenesis.
    Jala VR; Appaji Rao N; Savithri HS
    Biochem J; 2003 Feb; 369(Pt 3):469-76. PubMed ID: 12392447
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The role of Glu74 and Tyr82 in the reaction catalyzed by sheep liver cytosolic serine hydroxymethyltransferase.
    Rao JV; Prakash V; Rao NA; Savithri HS
    Eur J Biochem; 2000 Oct; 267(19):5967-76. PubMed ID: 10998057
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Conformational transitions driven by pyridoxal-5'-phosphate uptake in the psychrophilic serine hydroxymethyltransferase from Psychromonas ingrahamii.
    Angelaccio S; Dworkowski F; Di Bello A; Milano T; Capitani G; Pascarella S
    Proteins; 2014 Oct; 82(10):2831-41. PubMed ID: 25044250
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Role of tyrosine 65 in the mechanism of serine hydroxymethyltransferase.
    Contestabile R; Angelaccio S; Bossa F; Wright HT; Scarsdale N; Kazanina G; Schirch V
    Biochemistry; 2000 Jun; 39(25):7492-500. PubMed ID: 10858298
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Asp-89: a critical residue in maintaining the oligomeric structure of sheep liver cytosolic serine hydroxymethyltransferase.
    Krishna Rao JV; Jagath JR; Sharma B; Appaji Rao N; Savithri HS
    Biochem J; 1999 Oct; 343 Pt 1(Pt 1):257-63. PubMed ID: 10493937
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The role of lysine-256 in the structure and function of sheep liver recombinant serine hydroxymethyltransferase.
    Talwar R; Jagath JR; Datta A; Prakash V; Savithri HS; Rao NA
    Acta Biochim Pol; 1997; 44(4):679-88. PubMed ID: 9584848
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Crystal structure of binary and ternary complexes of serine hydroxymethyltransferase from Bacillus stearothermophilus: insights into the catalytic mechanism.
    Trivedi V; Gupta A; Jala VR; Saravanan P; Rao GS; Rao NA; Savithri HS; Subramanya HS
    J Biol Chem; 2002 May; 277(19):17161-9. PubMed ID: 11877399
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mutational, kinetic, and NMR studies of the roles of conserved glutamate residues and of lysine-39 in the mechanism of the MutT pyrophosphohydrolase.
    Harris TK; Wu G; Massiah MA; Mildvan AS
    Biochemistry; 2000 Feb; 39(7):1655-74. PubMed ID: 10677214
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.