329 related articles for article (PubMed ID: 12439601)
1. A mathematical model of in vivo methotrexate accumulation in acute lymphoblastic leukemia.
Panetta JC; Yanishevski Y; Pui CH; Sandlund JT; Rubnitz J; Rivera GK; Ribeiro R; Evans WE; Relling MV
Cancer Chemother Pharmacol; 2002 Nov; 50(5):419-28. PubMed ID: 12439601
[TBL] [Abstract][Full Text] [Related]
2. Methotrexate intracellular disposition in acute lymphoblastic leukemia: a mathematical model of gamma-glutamyl hydrolase activity.
Panetta JC; Wall A; Pui CH; Relling MV; Evans WE
Clin Cancer Res; 2002 Jul; 8(7):2423-9. PubMed ID: 12114448
[TBL] [Abstract][Full Text] [Related]
3. Modeling mechanisms of in vivo variability in methotrexate accumulation and folate pathway inhibition in acute lymphoblastic leukemia cells.
Panetta JC; Sparreboom A; Pui CH; Relling MV; Evans WE
PLoS Comput Biol; 2010 Dec; 6(12):e1001019. PubMed ID: 21152005
[TBL] [Abstract][Full Text] [Related]
4. Differences in folylpolyglutamate synthetase and dihydrofolate reductase expression in human B-lineage versus T-lineage leukemic lymphoblasts: mechanisms for lineage differences in methotrexate polyglutamylation and cytotoxicity.
Galpin AJ; Schuetz JD; Masson E; Yanishevski Y; Synold TW; Barredo JC; Pui CH; Relling MV; Evans WE
Mol Pharmacol; 1997 Jul; 52(1):155-63. PubMed ID: 9224825
[TBL] [Abstract][Full Text] [Related]
5. Pharmacogenomics of intracellular methotrexate polyglutamates in patients' leukemia cells in vivo.
Lopez-Lopez E; Autry RJ; Smith C; Yang W; Paugh SW; Panetta JC; Crews KR; Bonten EJ; Smart B; Pei D; McCorkle JR; Diouf B; Roberts KG; Shi L; Pounds S; Cheng C; Mullighan CG; Pui CH; Relling MV; Evans WE
J Clin Invest; 2020 Dec; 130(12):6600-6615. PubMed ID: 33164984
[TBL] [Abstract][Full Text] [Related]
6. gamma-Glutamyl hydrolase and folylpolyglutamate synthetase activities predict polyglutamylation of methotrexate in acute leukemias.
Longo GS; Gorlick R; Tong WP; Lin S; Steinherz P; Bertino JR
Oncol Res; 1997; 9(5):259-63. PubMed ID: 9306433
[TBL] [Abstract][Full Text] [Related]
7. Accumulation of methotrexate polyglutamates in lymphoblasts is a determinant of antileukemic effects in vivo. A rationale for high-dose methotrexate.
Masson E; Relling MV; Synold TW; Liu Q; Schuetz JD; Sandlund JT; Pui CH; Evans WE
J Clin Invest; 1996 Jan; 97(1):73-80. PubMed ID: 8550853
[TBL] [Abstract][Full Text] [Related]
8. Accumulation of methotrexate and methotrexate polyglutamates in lymphoblasts and treatment outcome in children with B-progenitor-cell acute lymphoblastic leukemia: a Pediatric Oncology Group study.
Whitehead VM; Shuster JJ; Vuchich MJ; Mahoney DH; Lauer SJ; Payment C; Koch PA; Cooley LD; Look AT; Pullen DJ; Camitta B
Leukemia; 2005 Apr; 19(4):533-6. PubMed ID: 15716987
[TBL] [Abstract][Full Text] [Related]
9. Blast cell methotrexate-polyglutamate accumulation in vivo differs by lineage, ploidy, and methotrexate dose in acute lymphoblastic leukemia.
Synold TW; Relling MV; Boyett JM; Rivera GK; Sandlund JT; Mahmoud H; Crist WM; Pui CH; Evans WE
J Clin Invest; 1994 Nov; 94(5):1996-2001. PubMed ID: 7525652
[TBL] [Abstract][Full Text] [Related]
10. Differences in constitutive and post-methotrexate folylpolyglutamate synthetase activity in B-lineage and T-lineage leukemia.
Barredo JC; Synold TW; Laver J; Relling MV; Pui CH; Priest DG; Evans WE
Blood; 1994 Jul; 84(2):564-9. PubMed ID: 7517720
[TBL] [Abstract][Full Text] [Related]
11. [Separation of methotrexate-polyglutamates by capillary electrophoresis and its application to the measurement of gamma-glutamyl hydrolase activity in human leukemia cells in culture].
Takemura Y; Kobayashi H; Sekiguchi S
Rinsho Byori; 1996 Jan; 44(1):51-6. PubMed ID: 8691640
[TBL] [Abstract][Full Text] [Related]
12. Folate pathway gene expression differs in subtypes of acute lymphoblastic leukemia and influences methotrexate pharmacodynamics.
Kager L; Cheok M; Yang W; Zaza G; Cheng Q; Panetta JC; Pui CH; Downing JR; Relling MV; Evans WE
J Clin Invest; 2005 Jan; 115(1):110-7. PubMed ID: 15630450
[TBL] [Abstract][Full Text] [Related]
13. Effect of methotrexate polyglutamates on thioguanine nucleotide concentrations during continuation therapy of acute lymphoblastic leukemia with mercaptopurine.
Dervieux T; Hancock M; Evans W; Pui CH; Relling MV
Leukemia; 2002 Feb; 16(2):209-12. PubMed ID: 11840287
[TBL] [Abstract][Full Text] [Related]
14. [Primary study on establishment of namalwa 12/MTX resistant cell strain and its mechanism].
Chen J; Gu LJ; Ying DM; Shen M; Wu HJ
Ai Zheng; 2002 Dec; 21(12):1335-40. PubMed ID: 12520743
[TBL] [Abstract][Full Text] [Related]
15. Accumulation of high levels of methotrexate polyglutamates in lymphoblasts from children with hyperdiploid (greater than 50 chromosomes) B-lineage acute lymphoblastic leukemia: a Pediatric Oncology Group study.
Whitehead VM; Vuchich MJ; Lauer SJ; Mahoney D; Carroll AJ; Shuster JJ; Esseltine DW; Payment C; Look AT; Akabutu J
Blood; 1992 Sep; 80(5):1316-23. PubMed ID: 1381244
[TBL] [Abstract][Full Text] [Related]
16. Reduced folate carrier expression in acute lymphoblastic leukemia: a mechanism for ploidy but not lineage differences in methotrexate accumulation.
Belkov VM; Krynetski EY; Schuetz JD; Yanishevski Y; Masson E; Mathew S; Raimondi S; Pui CH; Relling MV; Evans WE
Blood; 1999 Mar; 93(5):1643-50. PubMed ID: 10029593
[TBL] [Abstract][Full Text] [Related]
17. Shortening infusion time for high-dose methotrexate alters antileukemic effects: a randomized prospective clinical trial.
Mikkelsen TS; Sparreboom A; Cheng C; Zhou Y; Boyett JM; Raimondi SC; Panetta JC; Bowman WP; Sandlund JT; Pui CH; Relling MV; Evans WE
J Clin Oncol; 2011 May; 29(13):1771-8. PubMed ID: 21444869
[TBL] [Abstract][Full Text] [Related]
18. Evidence for negative feedback of extracellular methotrexate on blasts of acute lymphoblastic leukemia in vitro.
Hum MC; Smith AK; Lark RH; Winick NJ; Kamen BA
Pharmacotherapy; 1997; 17(6):1260-6. PubMed ID: 9399609
[TBL] [Abstract][Full Text] [Related]
19. The impact of high-dose methotrexate on intracellular 6-mercaptopurine disposition during interval therapy of childhood acute lymphoblastic leukemia.
Adam de Beaumais T; Dervieux T; Fakhoury M; Medard Y; Azougagh S; Zhang D; Yakouben K; Jacqz-Aigrain E
Cancer Chemother Pharmacol; 2010 Sep; 66(4):653-8. PubMed ID: 20033410
[TBL] [Abstract][Full Text] [Related]
20. Intracellular disposition of methotrexate in acute lymphoblastic leukemia in children.
de Beaumais TA; Jacqz-Aigrain E
Curr Drug Metab; 2012 Jul; 13(6):822-34. PubMed ID: 22571483
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
