213 related articles for article (PubMed ID: 12441002)
1. Molecular cloning and subcellular distribution of the novel PDE4B4 cAMP-specific phosphodiesterase isoform.
Shepherd M; McSorley T; Olsen AE; Johnston LA; Thomson NC; Baillie GS; Houslay MD; Bolger GB
Biochem J; 2003 Mar; 370(Pt 2):429-38. PubMed ID: 12441002
[TBL] [Abstract][Full Text] [Related]
2. Long PDE4 cAMP specific phosphodiesterases are activated by protein kinase A-mediated phosphorylation of a single serine residue in Upstream Conserved Region 1 (UCR1).
MacKenzie SJ; Baillie GS; McPhee I; MacKenzie C; Seamons R; McSorley T; Millen J; Beard MB; van Heeke G; Houslay MD
Br J Pharmacol; 2002 Jun; 136(3):421-33. PubMed ID: 12023945
[TBL] [Abstract][Full Text] [Related]
3. Molecular cloning and transient expression in COS7 cells of a novel human PDE4B cAMP-specific phosphodiesterase, HSPDE4B3.
Huston E; Lumb S; Russell A; Catterall C; Ross AH; Steele MR; Bolger GB; Perry MJ; Owens RJ; Houslay MD
Biochem J; 1997 Dec; 328 ( Pt 2)(Pt 2):549-58. PubMed ID: 9371714
[TBL] [Abstract][Full Text] [Related]
4. PDE4B5, a novel, super-short, brain-specific cAMP phosphodiesterase-4 variant whose isoform-specifying N-terminal region is identical to that of cAMP phosphodiesterase-4D6 (PDE4D6).
Cheung YF; Kan Z; Garrett-Engele P; Gall I; Murdoch H; Baillie GS; Camargo LM; Johnson JM; Houslay MD; Castle JC
J Pharmacol Exp Ther; 2007 Aug; 322(2):600-9. PubMed ID: 17519386
[TBL] [Abstract][Full Text] [Related]
5. Identification and characterization of PDE4A11, a novel, widely expressed long isoform encoded by the human PDE4A cAMP phosphodiesterase gene.
Wallace DA; Johnston LA; Huston E; MacMaster D; Houslay TM; Cheung YF; Campbell L; Millen JE; Smith RA; Gall I; Knowles RG; Sullivan M; Houslay MD
Mol Pharmacol; 2005 Jun; 67(6):1920-34. PubMed ID: 15738310
[TBL] [Abstract][Full Text] [Related]
6. Characterization of five different proteins produced by alternatively spliced mRNAs from the human cAMP-specific phosphodiesterase PDE4D gene.
Bolger GB; Erdogan S; Jones RE; Loughney K; Scotland G; Hoffmann R; Wilkinson I; Farrell C; Houslay MD
Biochem J; 1997 Dec; 328 ( Pt 2)(Pt 2):539-48. PubMed ID: 9371713
[TBL] [Abstract][Full Text] [Related]
7. Identification and characterization of the human homologue of the short PDE4A cAMP-specific phosphodiesterase RD1 (PDE4A1) by analysis of the human HSPDE4A gene locus located at chromosome 19p13.2.
Sullivan M; Rena G; Begg F; Gordon L; Olsen AS; Houslay MD
Biochem J; 1998 Aug; 333 ( Pt 3)(Pt 3):693-703. PubMed ID: 9677330
[TBL] [Abstract][Full Text] [Related]
8. Molecular cloning, genomic positioning, promoter identification, and characterization of the novel cyclic amp-specific phosphodiesterase PDE4A10.
Rena G; Begg F; Ross A; MacKenzie C; McPhee I; Campbell L; Huston E; Sullivan M; Houslay MD
Mol Pharmacol; 2001 May; 59(5):996-1011. PubMed ID: 11306681
[TBL] [Abstract][Full Text] [Related]
9. Human PDE4A8, a novel brain-expressed PDE4 cAMP-specific phosphodiesterase that has undergone rapid evolutionary change.
Mackenzie KF; Topping EC; Bugaj-Gaweda B; Deng C; Cheung YF; Olsen AE; Stockard CR; High Mitchell L; Baillie GS; Grizzle WE; De Vivo M; Houslay MD; Wang D; Bolger GB
Biochem J; 2008 Apr; 411(2):361-9. PubMed ID: 18095939
[TBL] [Abstract][Full Text] [Related]
10. In resting COS1 cells a dominant negative approach shows that specific, anchored PDE4 cAMP phosphodiesterase isoforms gate the activation, by basal cyclic AMP production, of AKAP-tethered protein kinase A type II located in the centrosomal region.
McCahill A; McSorley T; Huston E; Hill EV; Lynch MJ; Gall I; Keryer G; Lygren B; Tasken K; van Heeke G; Houslay MD
Cell Signal; 2005 Sep; 17(9):1158-73. PubMed ID: 15905070
[TBL] [Abstract][Full Text] [Related]
11. Activation and induction of cyclic AMP phosphodiesterase (PDE4) in rat pulmonary microvascular endothelial cells.
Zhu B; Kelly J; Vemavarapu L; Thompson WJ; Strada SJ
Biochem Pharmacol; 2004 Aug; 68(3):479-91. PubMed ID: 15242814
[TBL] [Abstract][Full Text] [Related]
12. UCR1 and UCR2 domains unique to the cAMP-specific phosphodiesterase family form a discrete module via electrostatic interactions.
Beard MB; Olsen AE; Jones RE; Erdogan S; Houslay MD; Bolger GB
J Biol Chem; 2000 Apr; 275(14):10349-58. PubMed ID: 10744723
[TBL] [Abstract][Full Text] [Related]
13. Attenuation of the activity of the cAMP-specific phosphodiesterase PDE4A5 by interaction with the immunophilin XAP2.
Bolger GB; Peden AH; Steele MR; MacKenzie C; McEwan DG; Wallace DA; Huston E; Baillie GS; Houslay MD
J Biol Chem; 2003 Aug; 278(35):33351-63. PubMed ID: 12810716
[TBL] [Abstract][Full Text] [Related]
14. Alternative splicing of cAMP-specific phosphodiesterase mRNA transcripts. Characterization of a novel tissue-specific isoform, RNPDE4A8.
Bolger GB; McPhee I; Houslay MD
J Biol Chem; 1996 Jan; 271(2):1065-71. PubMed ID: 8557632
[TBL] [Abstract][Full Text] [Related]
15. Regulation of distinct cyclic AMP-specific phosphodiesterase (phosphodiesterase type 4) isozymes in human monocytic cells.
Verghese MW; McConnell RT; Lenhard JM; Hamacher L; Jin SL
Mol Pharmacol; 1995 Jun; 47(6):1164-71. PubMed ID: 7603456
[TBL] [Abstract][Full Text] [Related]
16. In addition to the SH3 binding region, multiple regions within the N-terminal noncatalytic portion of the cAMP-specific phosphodiesterase, PDE4A5, contribute to its intracellular targeting.
Beard MB; Huston E; Campbell L; Gall I; McPhee I; Yarwood S; Scotland G; Houslay MD
Cell Signal; 2002 May; 14(5):453-65. PubMed ID: 11882390
[TBL] [Abstract][Full Text] [Related]
17. Identification, characterization and regional distribution in brain of RPDE-6 (RNPDE4A5), a novel splice variant of the PDE4A cyclic AMP phosphodiesterase family.
McPhee I; Pooley L; Lobban M; Bolger G; Houslay MD
Biochem J; 1995 Sep; 310 ( Pt 3)(Pt 3):965-74. PubMed ID: 7575434
[TBL] [Abstract][Full Text] [Related]
18. Human phosphodiesterase 4A: characterization of full-length and truncated enzymes expressed in COS cells.
Owens RJ; Catterall C; Batty D; Jappy J; Russell A; Smith B; O'Connell J; Perry MJ
Biochem J; 1997 Aug; 326 ( Pt 1)(Pt 1):53-60. PubMed ID: 9337850
[TBL] [Abstract][Full Text] [Related]
19. Cloning and characterization of novel PDE4D isoforms PDE4D6 and PDE4D7.
Wang D; Deng C; Bugaj-Gaweda B; Kwan M; Gunwaldsen C; Leonard C; Xin X; Hu Y; Unterbeck A; De Vivo M
Cell Signal; 2003 Sep; 15(9):883-91. PubMed ID: 12834813
[TBL] [Abstract][Full Text] [Related]
20. Differential CNS expression of alternative mRNA isoforms of the mammalian genes encoding cAMP-specific phosphodiesterases.
Bolger GB; Rodgers L; Riggs M
Gene; 1994 Nov; 149(2):237-44. PubMed ID: 7958996
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]