BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

116 related articles for article (PubMed ID: 12442256)

  • 1. Protein expression analysis of drug-mediated hepatotoxicity in the Sprague-Dawley rat.
    Man WJ; White IR; Bryant D; Bugelski P; Camilleri P; Cutler P; Heald G; Lord PG; Wood J; Kramer K
    Proteomics; 2002 Nov; 2(11):1577-85. PubMed ID: 12442256
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification of genes implicated in methapyrilene-induced hepatotoxicity by comparing differential gene expression in target and nontarget tissue.
    Auman JT; Chou J; Gerrish K; Huang Q; Jayadev S; Blanchard K; Paules RS
    Environ Health Perspect; 2007 Apr; 115(4):572-8. PubMed ID: 17450226
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Systems toxicology: integrated genomic, proteomic and metabonomic analysis of methapyrilene induced hepatotoxicity in the rat.
    Craig A; Sidaway J; Holmes E; Orton T; Jackson D; Rowlinson R; Nickson J; Tonge R; Wilson I; Nicholson J
    J Proteome Res; 2006 Jul; 5(7):1586-601. PubMed ID: 16823966
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Gene expression profiling of methapyrilene-induced hepatotoxicity in rat.
    Uehara T; Kiyosawa N; Hirode M; Omura K; Shimizu T; Ono A; Mizukawa Y; Miyagishima T; Nagao T; Urushidani T
    J Toxicol Sci; 2008 Feb; 33(1):37-50. PubMed ID: 18303183
    [TBL] [Abstract][Full Text] [Related]  

  • 5. In vitro proteomic analysis of methapyrilene toxicity in rat hepatocytes reveals effects on intermediary metabolism.
    Braeuning A; Oberemm A; Heise T; Gundert-Remy U; Hengstler JG; Lampen A
    Arch Toxicol; 2019 Feb; 93(2):369-383. PubMed ID: 30467583
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Protein expression changes in the Sprague Dawley rat liver proteome following administration of peroxisome proliferator activated receptor alpha and gamma ligands.
    White IR; Man WJ; Bryant D; Bugelski P; Camilleri P; Cutler P; Hayes W; Holbrook JD; Kramer K; Lord PG; Wood J
    Proteomics; 2003 Apr; 3(4):505-12. PubMed ID: 12687617
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Methapyrilene toxicity: anchorage of pathologic observations to gene expression alterations.
    Hamadeh HK; Knight BL; Haugen AC; Sieber S; Amin RP; Bushel PR; Stoll R; Blanchard K; Jayadev S; Tennant RW; Cunningham ML; Afshari CA; Paules RS
    Toxicol Pathol; 2002; 30(4):470-82. PubMed ID: 12187938
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Quantitative targeted bile acid profiling as new markers for DILI in a model of methapyrilene-induced liver injury in rats.
    Slopianka M; Herrmann A; Pavkovic M; Ellinger-Ziegelbauer H; Ernst R; Mally A; Keck M; Riefke B
    Toxicology; 2017 Jul; 386():1-10. PubMed ID: 28529062
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Interlaboratory evaluation of rat hepatic gene expression changes induced by methapyrilene.
    Waring JF; Ulrich RG; Flint N; Morfitt D; Kalkuhl A; Staedtler F; Lawton M; Beekman JM; Suter L
    Environ Health Perspect; 2004 Mar; 112(4):439-48. PubMed ID: 15033593
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Oxidative stress/reactive metabolite gene expression signature in rat liver detects idiosyncratic hepatotoxicants.
    Leone A; Nie A; Brandon Parker J; Sawant S; Piechta LA; Kelley MF; Mark Kao L; Jim Proctor S; Verheyen G; Johnson MD; Lord PG; McMillian MK
    Toxicol Appl Pharmacol; 2014 Mar; 275(3):189-97. PubMed ID: 24486436
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A novel transcriptomics based in vitro method to compare and predict hepatotoxicity based on mode of action.
    De Abrew KN; Overmann GJ; Adams RL; Tiesman JP; Dunavent J; Shan YK; Carr GJ; Daston GP; Naciff JM
    Toxicology; 2015 Feb; 328():29-39. PubMed ID: 25475144
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Covalent protein modifications and gene expression changes in rodent liver following administration of methapyrilene: a study using two-dimensional electrophoresis.
    Anderson NL; Copple DC; Bendele RA; Probst GS; Richardson FC
    Fundam Appl Toxicol; 1992 May; 18(4):570-80. PubMed ID: 1526369
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Combination of 'omics' data to investigate the mechanism(s) of hydrazine-induced hepatotoxicity in rats and to identify potential biomarkers.
    Klenø TG; Kiehr B; Baunsgaard D; Sidelmann UG
    Biomarkers; 2004; 9(2):116-38. PubMed ID: 15370871
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Principal component analysis of mass spectra of peptides generated from the tryptic digestion of protein mixtures.
    Bryant DK; Monté S; Man WJ; Kramer K; Bugelski P; Neville W; White IR; Camilleri P
    Rapid Commun Mass Spectrom; 2001; 15(6):418-27. PubMed ID: 11291120
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Toward the identification of liver toxicity markers: a proteome study in human cell culture and rats.
    Thome-Kromer B; Bonk I; Klatt M; Nebrich G; Taufmann M; Bryant S; Wacker U; Köpke A
    Proteomics; 2003 Oct; 3(10):1835-62. PubMed ID: 14625847
    [TBL] [Abstract][Full Text] [Related]  

  • 16. NTP Hepatotoxicity Studies of the Liver Carcinogen Methapyrilene Hydrochloride (CAS No. 135-23-9) Administered in Feed to Male F344/N Rats.
    Toxic Rep Ser; 2000 Feb; 46():1-C7. PubMed ID: 11986676
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Methapyrilene hepatotoxicity is associated with oxidative stress, mitochondrial disfunction and is prevented by the Ca2+ channel blocker verapamil.
    Ratra GS; Morgan WA; Mullervy J; Powell CJ; Wright MC
    Toxicology; 1998 Sep; 130(2-3):79-93. PubMed ID: 9865476
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Advantages of glutamate dehydrogenase as a blood biomarker of acute hepatic injury in rats.
    O'Brien PJ; Slaughter MR; Polley SR; Kramer K
    Lab Anim; 2002 Jul; 36(3):313-21. PubMed ID: 12144742
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Dose-responses in rat hepatic protein modification and expression following exposure to the rat hepatocarcinogen methapyrilene.
    Richardson FC; Horn DM; Anderson NL
    Carcinogenesis; 1994 Feb; 15(2):325-9. PubMed ID: 8313526
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effect of methapyrilene hydrochloride on hepatic intracellular iron metabolism in vivo and in vitro.
    Kindrat I; Dreval K; Shpyleva S; Tryndyak V; de Conti A; Mudalige TK; Chen T; Erstenyuk AM; Beland FA; Pogribny IP
    Toxicol Lett; 2017 Nov; 281():65-73. PubMed ID: 28935588
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.