These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

141 related articles for article (PubMed ID: 12443789)

  • 1. Scanning the prime-site substrate specificity of proteolytic enzymes: a novel assay based on ligand-enhanced lanthanide ion fluorescence.
    Barrios AM; Craik CS
    Bioorg Med Chem Lett; 2002 Dec; 12(24):3619-23. PubMed ID: 12443789
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Determination of the P1', P2' and P3' subsite-specificity of factor Xa.
    Ludeman JP; Pike RN; Bromfield KM; Duggan PJ; Cianci J; Le Bonniec B; Whisstock JC; Bottomley SP
    Int J Biochem Cell Biol; 2003 Feb; 35(2):221-5. PubMed ID: 12479872
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis of positional-scanning libraries of fluorogenic peptide substrates to define the extended substrate specificity of plasmin and thrombin.
    Backes BJ; Harris JL; Leonetti F; Craik CS; Ellman JA
    Nat Biotechnol; 2000 Feb; 18(2):187-93. PubMed ID: 10657126
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Active-site specificity of digestive aspartic peptidases from the four species of Plasmodium that infect humans using chromogenic combinatorial peptide libraries.
    Beyer BB; Johnson JV; Chung AY; Li T; Madabushi A; Agbandje-McKenna M; McKenna R; Dame JB; Dunn BM
    Biochemistry; 2005 Feb; 44(6):1768-79. PubMed ID: 15697202
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A strategy to profile prime and non-prime proteolytic substrate specificity.
    Petrassi HM; Williams JA; Li J; Tumanut C; Ek J; Nakai T; Masick B; Backes BJ; Harris JL
    Bioorg Med Chem Lett; 2005 Jun; 15(12):3162-6. PubMed ID: 15878267
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Substrate profiling of deubiquitin hydrolases with a positional scanning library and mass spectrometry.
    Mason DE; Ek J; Peters EC; Harris JL
    Biochemistry; 2004 Jun; 43(21):6535-44. PubMed ID: 15157086
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Biochemical characterization of prostasin, a channel activating protease.
    Shipway A; Danahay H; Williams JA; Tully DC; Backes BJ; Harris JL
    Biochem Biophys Res Commun; 2004 Nov; 324(2):953-63. PubMed ID: 15474520
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Characterization of the P2' and P3' specificities of thrombin using fluorescence-quenched substrates and mapping of the subsites by mutagenesis.
    Le Bonniec BF; Myles T; Johnson T; Knight CG; Tapparelli C; Stone SR
    Biochemistry; 1996 Jun; 35(22):7114-22. PubMed ID: 8679538
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis of a HyCoSuL peptide substrate library to dissect protease substrate specificity.
    Poreba M; Salvesen GS; Drag M
    Nat Protoc; 2017 Oct; 12(10):2189-2214. PubMed ID: 28933778
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design of synthetic hexapeptide substrates for prostate-specific antigen using single-position minilibraries.
    Yang CF; Porter ES; Boths J; Kanyi D; Hsieh M; Cooperman BS
    J Pept Res; 1999 Nov; 54(5):444-8. PubMed ID: 10563510
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Active site specificity profiling of the matrix metalloproteinase family: Proteomic identification of 4300 cleavage sites by nine MMPs explored with structural and synthetic peptide cleavage analyses.
    Eckhard U; Huesgen PF; Schilling O; Bellac CL; Butler GS; Cox JH; Dufour A; Goebeler V; Kappelhoff R; Keller UAD; Klein T; Lange PF; Marino G; Morrison CJ; Prudova A; Rodriguez D; Starr AE; Wang Y; Overall CM
    Matrix Biol; 2016 Jan; 49():37-60. PubMed ID: 26407638
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Protease specificity profiling by tandem mass spectrometry using proteome-derived peptide libraries.
    Schilling O; auf dem Keller U; Overall CM
    Methods Mol Biol; 2011; 753():257-72. PubMed ID: 21604128
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Recent advances and concepts in substrate specificity determination of proteases using tailored libraries of fluorogenic substrates with unnatural amino acids.
    Rut W; Kasperkiewicz P; Byzia A; Poreba M; Groborz K; Drag M
    Biol Chem; 2015 Apr; 396(4):329-37. PubMed ID: 25719315
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Thrombin specificity. Requirement for apolar amino acids adjacent to the thrombin cleavage site of polypeptide substrate.
    Chang JY
    Eur J Biochem; 1985 Sep; 151(2):217-24. PubMed ID: 2863141
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, synthesis, and evaluation of matrix metalloprotease inhibitors bearing cyclopropane-derived peptidomimetics as P1' and P2' replacements.
    Reichelt A; Gaul C; Frey RR; Kennedy A; Martin SF
    J Org Chem; 2002 Jun; 67(12):4062-75. PubMed ID: 12054939
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Proteolytic fingerprinting of complex biological samples using combinatorial libraries of fluorogenic probes.
    Jambunathan K; Watson DS; Kodukula K; Galande AK
    Curr Protoc Protein Sci; 2012 Nov; Chapter 21():21.22.1-21.22.14. PubMed ID: 23151745
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Arg143 and Lys192 of the human mast cell chymase mediate the preference for acidic amino acids in position P2' of substrates.
    Andersson MK; Thorpe M; Hellman L
    FEBS J; 2010 May; 277(10):2255-67. PubMed ID: 20423454
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Using peptide libraries to identify optimal cleavage motifs for proteolytic enzymes.
    Turk BE; Cantley LC
    Methods; 2004 Apr; 32(4):398-405. PubMed ID: 15003602
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Positional scanning synthetic combinatorial libraries for substrate profiling.
    Schneider EL; Craik CS
    Methods Mol Biol; 2009; 539():59-78. PubMed ID: 19377970
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Activity based fingerprinting of proteases using FRET peptides.
    Sun H; Panicker RC; Yao SQ
    Biopolymers; 2007; 88(2):141-9. PubMed ID: 17206627
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.