525 related articles for article (PubMed ID: 12444075)
1. Structural requirements for potent anti-human immunodeficiency virus (HIV) and sperm-immobilizing activities of cyclohexenyl thiourea and urea non-nucleoside inhibitors of HIV-1 reverse transcriptase.
D'Cruz OJ; Venkatachalam TK; Mao C; Qazi S; Uckun FM
Biol Reprod; 2002 Dec; 67(6):1959-74. PubMed ID: 12444075
[TBL] [Abstract][Full Text] [Related]
2. Potent dual anti-HIV and spermicidal activities of novel oxovanadium(V) complexes with thiourea non-nucleoside inhibitors of HIV-1 reverse transcriptase.
D'Cruz OJ; Dong Y; Uckun FM
Biochem Biophys Res Commun; 2003 Mar; 302(2):253-64. PubMed ID: 12604339
[TBL] [Abstract][Full Text] [Related]
3. Novel thiourea compounds as dual-function microbicides.
D'Cruz OJ; Venkatachalam TK; Uckun FM
Biol Reprod; 2000 Jul; 63(1):196-205. PubMed ID: 10859260
[TBL] [Abstract][Full Text] [Related]
4. Novel derivatives of phenethyl-5-bromopyridylthiourea and dihydroalkoxybenzyloxopyrimidine are dual-function spermicides with potent anti-human immunodeficiency virus activity.
D'Cruz OJ; Uckun FM
Biol Reprod; 1999 Jun; 60(6):1419-28. PubMed ID: 10330101
[TBL] [Abstract][Full Text] [Related]
5. N-[2-(1-cyclohexenyl)ethyl]-N'-[2-(5-bromopyridyl)]-thiourea and N'-[2-(1-cyclohexenyl)ethyl]-N'-[2-(5-chloropyridyl)]-thiourea as potent inhibitors of multidrug-resistant human immunodeficiency virus-1.
Uckun FM; Mao C; Pendergrass S; Maher D; Zhu D; Tuel-Ahlgren L; Venkatachalam TK
Bioorg Med Chem Lett; 1999 Sep; 9(18):2721-6. PubMed ID: 10509923
[TBL] [Abstract][Full Text] [Related]
6. A 13-week subchronic intravaginal toxicity study of the novel broad-spectrum anti-HIV and spermicidal agent, N-[2-(1-cyclohexenyl)ethyl]-N'-[2-(5-bromopyridyl)]-thiourea (PHI-346) in mice.
D'Cruz OJ; Waurzyniak B; Uckun FM
Toxicol Pathol; 2002; 30(6):687-95. PubMed ID: 12512870
[TBL] [Abstract][Full Text] [Related]
7. WHI-05, a novel bromo-methoxy substituted phenyl phosphate derivative of zidovudine, is a dual-action spermicide with potent anti-HIV activity.
D'Cruz OJ; Zhu Z; Yiv SH; Chen CL; Waurzyniak B; Uckun FM
Contraception; 1999 May; 59(5):319-31. PubMed ID: 10494486
[TBL] [Abstract][Full Text] [Related]
8. Synthesis, characterization and preclinical formulation of a dual-action phenyl phosphate derivative of bromo-methoxy zidovudine (compound WHI-07) with potent anti-HIV and spermicidal activities.
D'Cruz OJ; Shih MJ; Yiv SH; Chen CL; Uckun FM
Mol Hum Reprod; 1999 May; 5(5):421-32. PubMed ID: 10338365
[TBL] [Abstract][Full Text] [Related]
9. Aryl phosphate derivatives of bromo-methoxy-azidothymidine are dual-function spermicides with potent anti-human immunodeficiency virus.
D'Cruz OJ; Venkatachalam TK; Zhu Z; Shih MJ; Uckun FM
Biol Reprod; 1998 Sep; 59(3):503-15. PubMed ID: 9716547
[TBL] [Abstract][Full Text] [Related]
10. Piperidinylethyl, phenoxyethyl and fluoroethyl bromopyridyl thiourea compounds with potent anti-HIV activity.
Venkatachalam TK; Sudbec EA; Mao C; Uckun FM
Antivir Chem Chemother; 2000 Sep; 11(5):329-36. PubMed ID: 11142631
[TBL] [Abstract][Full Text] [Related]
11. Structural requirements for potent human spermicidal activity of dual-function aryl phosphate derivative of bromo-methoxy zidovudine (compound WHI-07).
D'Cruz OJ; Venkatachalam TK; Uckun FM
Biol Reprod; 2000 Jan; 62(1):37-44. PubMed ID: 10611065
[TBL] [Abstract][Full Text] [Related]
12. Structure-based design of N-[2-(1-piperidinylethyl)]-N'-[2-(5-bromopyridyl)]-thiourea and N-[2-(1-piperazinylethyl)]-N'-[2-(5-bromopyridyl)]-thiourea as potent non-nucleoside inhibitors of HIV-1 reverse transcriptase.
Mao C; Vig R; Venkatachalam TK; Sudbeck EA; Uckun FM
Bioorg Med Chem Lett; 1998 Aug; 8(16):2213-8. PubMed ID: 9873515
[TBL] [Abstract][Full Text] [Related]
13. Discovery of 2,5-dimethoxy-substituted 5-bromopyridyl thiourea (PHI-236) as a potent broad-spectrum anti-human immunodeficiency virus microbicide.
D'Cruz OJ; Uckun FM
Mol Hum Reprod; 2005 Oct; 11(10):767-77. PubMed ID: 16254003
[TBL] [Abstract][Full Text] [Related]
14. PHI-443: a novel noncontraceptive broad-spectrum anti-human immunodeficiency virus microbicide.
D'Cruz OJ; Samuel P; Uckun FM
Biol Reprod; 2004 Dec; 71(6):2037-47. PubMed ID: 15306558
[TBL] [Abstract][Full Text] [Related]
15. Structure-based design of non-nucleoside reverse transcriptase inhibitors of drug-resistant human immunodeficiency virus.
Mao C; Sudbeck EA; Venkatachalam TK; Uckun FM
Antivir Chem Chemother; 1999 Sep; 10(5):233-40. PubMed ID: 10574178
[TBL] [Abstract][Full Text] [Related]
16. A novel vaginal microbicide containing the rationally designed anti-HIV compound HI-443 (N'-[2-(2-thiophene)ethyl]-N'-[2-(5-bromopyridyl)] thiourea]).
D'Cruz OJ; Qazi S; Yiv S; Uckun FM
Expert Opin Investig Drugs; 2012 Mar; 21(3):265-79. PubMed ID: 22292483
[TBL] [Abstract][Full Text] [Related]
17. Importance of the alanine methyl ester side chain for the biological activity profile of dual-function phenyl phosphate derivatives of bromo-methoxy-zidovudine.
Venkatachalam TK; D'Cruz OJ; Uckun FM
Antivir Chem Chemother; 2000 Jan; 11(1):31-9. PubMed ID: 10693652
[TBL] [Abstract][Full Text] [Related]
18. Stereochemistry as a major determinant of the anti-HIV activity of chiral naphthyl thiourea compounds.
Venkatachalam TK; Mao C; Uckun FM
Antivir Chem Chemother; 2001 Jul; 12(4):213-21. PubMed ID: 11771730
[TBL] [Abstract][Full Text] [Related]
19. Novel broad-spectrum thiourea non-nucleoside inhibitors for the prevention of mucosal HIV transmission.
D'Cruz OJ; Uckun FM
Curr HIV Res; 2006 Jul; 4(3):329-45. PubMed ID: 16842085
[TBL] [Abstract][Full Text] [Related]
20. Quinoxalinylethylpyridylthioureas (QXPTs) as potent non-nucleoside HIV-1 reverse transcriptase (RT) inhibitors. Further SAR studies and identification of a novel orally bioavailable hydrazine-based antiviral agent.
Campiani G; Aiello F; Fabbrini M; Morelli E; Ramunno A; Armaroli S; Nacci V; Garofalo A; Greco G; Novellino E; Maga G; Spadari S; Bergamini A; Ventura L; Bongiovanni B; Capozzi M; Bolacchi F; Marini S; Coletta M; Guiso G; Caccia S
J Med Chem; 2001 Feb; 44(3):305-15. PubMed ID: 11462972
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]