BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

249 related articles for article (PubMed ID: 12444098)

  • 1. The Bloom syndrome helicase BLM interacts with TRF2 in ALT cells and promotes telomeric DNA synthesis.
    Stavropoulos DJ; Bradshaw PS; Li X; Pasic I; Truong K; Ikura M; Ungrin M; Meyn MS
    Hum Mol Genet; 2002 Dec; 11(25):3135-44. PubMed ID: 12444098
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Association and regulation of the BLM helicase by the telomere proteins TRF1 and TRF2.
    Lillard-Wetherell K; Machwe A; Langland GT; Combs KA; Behbehani GK; Schonberg SA; German J; Turchi JJ; Orren DK; Groden J
    Hum Mol Genet; 2004 Sep; 13(17):1919-32. PubMed ID: 15229185
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Telomere and ribosomal DNA repeats are chromosomal targets of the bloom syndrome DNA helicase.
    Schawalder J; Paric E; Neff NF
    BMC Cell Biol; 2003 Oct; 4():15. PubMed ID: 14577841
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Telomere-binding protein TRF2 binds to and stimulates the Werner and Bloom syndrome helicases.
    Opresko PL; von Kobbe C; Laine JP; Harrigan J; Hickson ID; Bohr VA
    J Biol Chem; 2002 Oct; 277(43):41110-9. PubMed ID: 12181313
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Telomerase-associated protein 1, HSP90, and topoisomerase IIalpha associate directly with the BLM helicase in immortalized cells using ALT and modulate its helicase activity using telomeric DNA substrates.
    Bhattacharyya S; Keirsey J; Russell B; Kavecansky J; Lillard-Wetherell K; Tahmaseb K; Turchi JJ; Groden J
    J Biol Chem; 2009 May; 284(22):14966-77. PubMed ID: 19329795
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Topoisomerase IIIalpha is required for normal proliferation and telomere stability in alternative lengthening of telomeres.
    Temime-Smaali N; Guittat L; Wenner T; Bayart E; Douarre C; Gomez D; Giraud-Panis MJ; Londono-Vallejo A; Gilson E; Amor-Guéret M; Riou JF
    EMBO J; 2008 May; 27(10):1513-24. PubMed ID: 18418389
    [TBL] [Abstract][Full Text] [Related]  

  • 7. BLM helicase unwinds lagging strand substrates to assemble the ALT telomere damage response.
    Jiang H; Zhang T; Kaur H; Shi T; Krishnan A; Kwon Y; Sung P; Greenberg RA
    Mol Cell; 2024 May; 84(9):1684-1698.e9. PubMed ID: 38593805
    [TBL] [Abstract][Full Text] [Related]  

  • 8. FANCD2 limits BLM-dependent telomere instability in the alternative lengthening of telomeres pathway.
    Root H; Larsen A; Komosa M; Al-Azri F; Li R; Bazett-Jones DP; Stephen Meyn M
    Hum Mol Genet; 2016 Aug; 25(15):3255-3268. PubMed ID: 27427384
    [TBL] [Abstract][Full Text] [Related]  

  • 9. BLM (the causative gene of Bloom syndrome) protein translocation into the nucleus by a nuclear localization signal.
    Kaneko H; Orii KO; Matsui E; Shimozawa N; Fukao T; Matsumoto T; Shimamoto A; Furuichi Y; Hayakawa S; Kasahara K; Kondo N
    Biochem Biophys Res Commun; 1997 Nov; 240(2):348-53. PubMed ID: 9388480
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The Werner syndrome helicase and exonuclease cooperate to resolve telomeric D loops in a manner regulated by TRF1 and TRF2.
    Opresko PL; Otterlei M; Graakjaer J; Bruheim P; Dawut L; Kølvraa S; May A; Seidman MM; Bohr VA
    Mol Cell; 2004 Jun; 14(6):763-74. PubMed ID: 15200954
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Alternative lengthening of telomeres is a self-perpetuating process in ALT-associated PML bodies.
    Zhang JM; Genois MM; Ouyang J; Lan L; Zou L
    Mol Cell; 2021 Mar; 81(5):1027-1042.e4. PubMed ID: 33453166
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Localization of the Bloom syndrome helicase to punctate nuclear structures and the nuclear matrix and regulation during the cell cycle: comparison with the Werner's syndrome helicase.
    Gharibyan V; Youssoufian H
    Mol Carcinog; 1999 Dec; 26(4):261-73. PubMed ID: 10569803
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Telomerase activity in cell lines and lymphoma originating from Bloom syndrome.
    Kaneko H; Morimoto W; Fukao T; Kasahara K; Kondo N
    Leuk Lymphoma; 2001 Aug; 42(4):757-60. PubMed ID: 11697506
    [TBL] [Abstract][Full Text] [Related]  

  • 14. POT1 stimulates RecQ helicases WRN and BLM to unwind telomeric DNA substrates.
    Opresko PL; Mason PA; Podell ER; Lei M; Hickson ID; Cech TR; Bohr VA
    J Biol Chem; 2005 Sep; 280(37):32069-80. PubMed ID: 16030011
    [TBL] [Abstract][Full Text] [Related]  

  • 15. BLM helicase complements disrupted type II telomere lengthening in telomerase-negative sgs1 yeast.
    Lillard-Wetherell K; Combs KA; Groden J
    Cancer Res; 2005 Jul; 65(13):5520-2. PubMed ID: 15994923
    [TBL] [Abstract][Full Text] [Related]  

  • 16. FANCM limits ALT activity by restricting telomeric replication stress induced by deregulated BLM and R-loops.
    Silva B; Pentz R; Figueira AM; Arora R; Lee YW; Hodson C; Wischnewski H; Deans AJ; Azzalin CM
    Nat Commun; 2019 May; 10(1):2253. PubMed ID: 31138795
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Functional interaction of p53 and BLM DNA helicase in apoptosis.
    Wang XW; Tseng A; Ellis NA; Spillare EA; Linke SP; Robles AI; Seker H; Yang Q; Hu P; Beresten S; Bemmels NA; Garfield S; Harris CC
    J Biol Chem; 2001 Aug; 276(35):32948-55. PubMed ID: 11399766
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Characterization of the nuclear localization signal in the DNA helicase responsible for Bloom syndrome.
    Hayakawa S; Kaneko H; Fukao T; Kasahara K; Matsumoto T; Furuichi Y; Kondo N
    Int J Mol Med; 2000 May; 5(5):477-84. PubMed ID: 10762650
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Nuclear structure in normal and Bloom syndrome cells.
    Yankiwski V; Marciniak RA; Guarente L; Neff NF
    Proc Natl Acad Sci U S A; 2000 May; 97(10):5214-9. PubMed ID: 10779560
    [TBL] [Abstract][Full Text] [Related]  

  • 20. FANCM, BRCA1, and BLM cooperatively resolve the replication stress at the ALT telomeres.
    Pan X; Drosopoulos WC; Sethi L; Madireddy A; Schildkraut CL; Zhang D
    Proc Natl Acad Sci U S A; 2017 Jul; 114(29):E5940-E5949. PubMed ID: 28673972
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.