BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

306 related articles for article (PubMed ID: 12447382)

  • 1. 53BP1 functions in an ATM-dependent checkpoint pathway that is constitutively activated in human cancer.
    DiTullio RA; Mochan TA; Venere M; Bartkova J; Sehested M; Bartek J; Halazonetis TD
    Nat Cell Biol; 2002 Dec; 4(12):998-1002. PubMed ID: 12447382
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 53BP1 and NFBD1/MDC1-Nbs1 function in parallel interacting pathways activating ataxia-telangiectasia mutated (ATM) in response to DNA damage.
    Mochan TA; Venere M; DiTullio RA; Halazonetis TD
    Cancer Res; 2003 Dec; 63(24):8586-91. PubMed ID: 14695167
    [TBL] [Abstract][Full Text] [Related]  

  • 3. p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks.
    Schultz LB; Chehab NH; Malikzay A; Halazonetis TD
    J Cell Biol; 2000 Dec; 151(7):1381-90. PubMed ID: 11134068
    [TBL] [Abstract][Full Text] [Related]  

  • 4. STAT-1 facilitates the ATM activated checkpoint pathway following DNA damage.
    Townsend PA; Cragg MS; Davidson SM; McCormick J; Barry S; Lawrence KM; Knight RA; Hubank M; Chen PL; Latchman DS; Stephanou A
    J Cell Sci; 2005 Apr; 118(Pt 8):1629-39. PubMed ID: 15784679
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Tumor suppressor p53 binding protein 1 (53BP1) is involved in DNA damage-signaling pathways.
    Rappold I; Iwabuchi K; Date T; Chen J
    J Cell Biol; 2001 Apr; 153(3):613-20. PubMed ID: 11331310
    [TBL] [Abstract][Full Text] [Related]  

  • 6. DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1.
    Fernandez-Capetillo O; Chen HT; Celeste A; Ward I; Romanienko PJ; Morales JC; Naka K; Xia Z; Camerini-Otero RD; Motoyama N; Carpenter PB; Bonner WM; Chen J; Nussenzweig A
    Nat Cell Biol; 2002 Dec; 4(12):993-7. PubMed ID: 12447390
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Phosphorylation and rapid relocalization of 53BP1 to nuclear foci upon DNA damage.
    Anderson L; Henderson C; Adachi Y
    Mol Cell Biol; 2001 Mar; 21(5):1719-29. PubMed ID: 11238909
    [TBL] [Abstract][Full Text] [Related]  

  • 8. 53BP1, an activator of ATM in response to DNA damage.
    Mochan TA; Venere M; DiTullio RA; Halazonetis TD
    DNA Repair (Amst); 2004; 3(8-9):945-52. PubMed ID: 15279780
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 53BP1, a mediator of the DNA damage checkpoint.
    Wang B; Matsuoka S; Carpenter PB; Elledge SJ
    Science; 2002 Nov; 298(5597):1435-8. PubMed ID: 12364621
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Indole-3-carbinol activates the ATM signaling pathway independent of DNA damage to stabilize p53 and induce G1 arrest of human mammary epithelial cells.
    Brew CT; Aronchik I; Hsu JC; Sheen JH; Dickson RB; Bjeldanes LF; Firestone GL
    Int J Cancer; 2006 Feb; 118(4):857-68. PubMed ID: 16152627
    [TBL] [Abstract][Full Text] [Related]  

  • 11. ATM signaling and 53BP1.
    Zgheib O; Huyen Y; DiTullio RA; Snyder A; Venere M; Stavridi ES; Halazonetis TD
    Radiother Oncol; 2005 Aug; 76(2):119-22. PubMed ID: 16024119
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Protein-protein interactions occur between p53 phosphoforms and ATM and 53BP1 at sites of exogenous DNA damage.
    Al Rashid ST; Harding SM; Law C; Coackley C; Bristow RG
    Radiat Res; 2011 May; 175(5):588-98. PubMed ID: 21361779
    [TBL] [Abstract][Full Text] [Related]  

  • 13. NFBD1, like 53BP1, is an early and redundant transducer mediating Chk2 phosphorylation in response to DNA damage.
    Peng A; Chen PL
    J Biol Chem; 2003 Mar; 278(11):8873-6. PubMed ID: 12551934
    [TBL] [Abstract][Full Text] [Related]  

  • 14. 53BP1 is required for class switch recombination.
    Ward IM; Reina-San-Martin B; Olaru A; Minn K; Tamada K; Lau JS; Cascalho M; Chen L; Nussenzweig A; Livak F; Nussenzweig MC; Chen J
    J Cell Biol; 2004 May; 165(4):459-64. PubMed ID: 15159415
    [TBL] [Abstract][Full Text] [Related]  

  • 15. p53 Binding protein 53BP1 is required for DNA damage responses and tumor suppression in mice.
    Ward IM; Minn K; van Deursen J; Chen J
    Mol Cell Biol; 2003 Apr; 23(7):2556-63. PubMed ID: 12640136
    [TBL] [Abstract][Full Text] [Related]  

  • 16. NFBD1/Mdc1 mediates ATR-dependent DNA damage response.
    Peng A; Chen PL
    Cancer Res; 2005 Feb; 65(4):1158-63. PubMed ID: 15734998
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Vaccinia-related kinase 1 (VRK1) is an upstream nucleosomal kinase required for the assembly of 53BP1 foci in response to ionizing radiation-induced DNA damage.
    Sanz-García M; Monsalve DM; Sevilla A; Lazo PA
    J Biol Chem; 2012 Jul; 287(28):23757-68. PubMed ID: 22621922
    [TBL] [Abstract][Full Text] [Related]  

  • 18. S1219 residue of 53BP1 is phosphorylated by ATM kinase upon DNA damage and required for proper execution of DNA damage response.
    Lee H; Kwak HJ; Cho IT; Park SH; Lee CH
    Biochem Biophys Res Commun; 2009 Jan; 378(1):32-6. PubMed ID: 18996087
    [TBL] [Abstract][Full Text] [Related]  

  • 19. 53BP1 represses mitotic catastrophe in syncytia elicited by the HIV-1 envelope.
    Perfettini JL; Nardacci R; Séror C; Raza SQ; Sepe S; Saïdi H; Brottes F; Amendola A; Subra F; Del Nonno F; Chessa L; D'Incecco A; Gougeon ML; Piacentini M; Kroemer G
    Cell Death Differ; 2010 May; 17(5):811-20. PubMed ID: 19876065
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Functional interaction of H2AX, NBS1, and p53 in ATM-dependent DNA damage responses and tumor suppression.
    Kang J; Ferguson D; Song H; Bassing C; Eckersdorff M; Alt FW; Xu Y
    Mol Cell Biol; 2005 Jan; 25(2):661-70. PubMed ID: 15632067
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.