These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

328 related articles for article (PubMed ID: 12447695)

  • 1. Pluripotent cell division cycles are driven by ectopic Cdk2, cyclin A/E and E2F activities.
    Stead E; White J; Faast R; Conn S; Goldstone S; Rathjen J; Dhingra U; Rathjen P; Walker D; Dalton S
    Oncogene; 2002 Nov; 21(54):8320-33. PubMed ID: 12447695
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cyclin E-cdk2 activation is associated with cell cycle arrest and inhibition of DNA replication induced by the thymidylate synthase inhibitor Tomudex.
    Yin MB; Guo B; Panadero A; Frank C; Wrzosek C; Slocum HK; Rustum YM
    Exp Cell Res; 1999 Feb; 247(1):189-99. PubMed ID: 10047461
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Regulation of E2F transcription by cyclin E-Cdk2 kinase mediated through p300/CBP co-activators.
    Morris L; Allen KE; La Thangue NB
    Nat Cell Biol; 2000 Apr; 2(4):232-9. PubMed ID: 10783242
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Expression and activity of the retinoblastoma protein (pRB)-family proteins, p107 and p130, during L6 myoblast differentiation.
    Kiess M; Gill RM; Hamel PA
    Cell Growth Differ; 1995 Oct; 6(10):1287-98. PubMed ID: 8845306
    [TBL] [Abstract][Full Text] [Related]  

  • 5. E1A modulates phosphorylation of p130 and p107 by differentially regulating the activity of G1/S cyclin/CDK complexes.
    Parreño M; Garriga J; Limón A; Albrecht JH; Graña X
    Oncogene; 2001 Aug; 20(35):4793-806. PubMed ID: 11521191
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The E2F-family proteins induce distinct cell cycle regulatory factors in p16-arrested, U343 astrocytoma cells.
    Dirks PB; Rutka JT; Hubbard SL; Mondal S; Hamel PA
    Oncogene; 1998 Aug; 17(7):867-76. PubMed ID: 9780003
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Restoration of retinoblastoma mediated signaling to Cdk2 results in cell cycle arrest.
    Strobeck MW; Fribourg AF; Puga A; Knudsen ES
    Oncogene; 2000 Apr; 19(15):1857-67. PubMed ID: 10773875
    [TBL] [Abstract][Full Text] [Related]  

  • 8. BCL-x(L) and BCL2 delay Myc-induced cell cycle entry through elevation of p27 and inhibition of G1 cyclin-dependent kinases.
    Greider C; Chattopadhyay A; Parkhurst C; Yang E
    Oncogene; 2002 Nov; 21(51):7765-75. PubMed ID: 12420213
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Adhesion-regulated G1 cell cycle arrest in epithelial cells requires the downregulation of c-Myc.
    Benaud CM; Dickson RB
    Oncogene; 2001 Jul; 20(33):4554-67. PubMed ID: 11494151
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Loss of cell cycle control by deregulation of cyclin-dependent kinase 2 kinase activity in Evi-1 transformed fibroblasts.
    Kilbey A; Stephens V; Bartholomew C
    Cell Growth Differ; 1999 Sep; 10(9):601-10. PubMed ID: 10511310
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inducible pRb2/p130 expression and growth-suppressive mechanisms: evidence of a pRb2/p130, p27Kip1, and cyclin E negative feedback regulatory loop.
    Howard CM; Claudio PP; De Luca A; Stiegler P; Jori FP; Safdar NM; Caputi M; Khalili K; Giordano A
    Cancer Res; 2000 May; 60(10):2737-44. PubMed ID: 10825149
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Site-directed mutant p21 proteins defective in both inhibition of E2F-regulated transcription and disruption of E2F-p130-cyclin-cdk2 complexes.
    Robles SJ; Shiyanov P; Aristodemo GT; Raychaudhuri P; Adami GR
    DNA Cell Biol; 1998 Jan; 17(1):9-18. PubMed ID: 9468218
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The cell-cycle regulated transcription factor B-Myb is phosphorylated by cyclin A/Cdk2 at sites that enhance its transactivation properties.
    Saville MK; Watson RJ
    Oncogene; 1998 Nov; 17(21):2679-89. PubMed ID: 9840932
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Developmental activation of the Rb-E2F pathway and establishment of cell cycle-regulated cyclin-dependent kinase activity during embryonic stem cell differentiation.
    White J; Stead E; Faast R; Conn S; Cartwright P; Dalton S
    Mol Biol Cell; 2005 Apr; 16(4):2018-27. PubMed ID: 15703208
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Disruption of the actin cytoskeleton leads to inhibition of mitogen-induced cyclin E expression, Cdk2 phosphorylation, and nuclear accumulation of the retinoblastoma protein-related p107 protein.
    Reshetnikova G; Barkan R; Popov B; Nikolsky N; Chang LS
    Exp Cell Res; 2000 Aug; 259(1):35-53. PubMed ID: 10942577
    [TBL] [Abstract][Full Text] [Related]  

  • 16. CaMK-II inhibition reduces cyclin D1 levels and enhances the association of p27kip1 with Cdk2 to cause G1 arrest in NIH 3T3 cells.
    Morris TA; DeLorenzo RJ; Tombes RM
    Exp Cell Res; 1998 May; 240(2):218-27. PubMed ID: 9596994
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Loss of p27Kip1 from cyclin E/cyclin-dependent kinase (CDK) 2 but not from cyclin D1/CDK4 complexes in cells transformed by polyamine biosynthetic enzymes.
    Ravanko K; Järvinen K; Paasinen-Sohns A; Hölttä E
    Cancer Res; 2000 Sep; 60(18):5244-53. PubMed ID: 11016654
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A role for a p21-E2F interaction during senescence arrest of normal human fibroblasts.
    Afshari CA; Nichols MA; Xiong Y; Mudryj M
    Cell Growth Differ; 1996 Aug; 7(8):979-88. PubMed ID: 8853893
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F.
    Leone G; DeGregori J; Sears R; Jakoi L; Nevins JR
    Nature; 1997 May; 387(6631):422-6. PubMed ID: 9163430
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ectopic expression of cyclin E in estrogen responsive cells abrogates antiestrogen mediated growth arrest.
    Dhillon NK; Mudryj M
    Oncogene; 2002 Jul; 21(30):4626-34. PubMed ID: 12096339
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.