BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

308 related articles for article (PubMed ID: 12450380)

  • 1. "Dilysine trigger" in transferrins probed by mutagenesis of lactoferrin: crystal structures of the R210G, R210E, and R210L mutants of human lactoferrin.
    Peterson NA; Arcus VL; Anderson BF; Tweedie JW; Jameson GB; Baker EN
    Biochemistry; 2002 Dec; 41(48):14167-75. PubMed ID: 12450380
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Crystal structure and iron-binding properties of the R210K mutant of the N-lobe of human lactoferrin: implications for iron release from transferrins.
    Peterson NA; Anderson BF; Jameson GB; Tweedie JW; Baker EN
    Biochemistry; 2000 Jun; 39(22):6625-33. PubMed ID: 10828980
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Crystal structures and iron release properties of mutants (K206A and K296A) that abolish the dilysine interaction in the N-lobe of human transferrin.
    Nurizzo D; Baker HM; He QY; MacGillivray RT; Mason AB; Woodworth RC; Baker EN
    Biochemistry; 2001 Feb; 40(6):1616-23. PubMed ID: 11327820
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mutation of the iron ligand His 249 to Glu in the N-lobe of human transferrin abolishes the dilysine "trigger" but does not significantly affect iron release.
    MacGillivray RT; Bewley MC; Smith CA; He QY; Mason AB; Woodworth RC; Baker EN
    Biochemistry; 2000 Feb; 39(6):1211-6. PubMed ID: 10684598
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Altered domain closure and iron binding in transferrins: the crystal structure of the Asp60Ser mutant of the amino-terminal half-molecule of human lactoferrin.
    Faber HR; Bland T; Day CL; Norris GE; Tweedie JW; Baker EN
    J Mol Biol; 1996 Feb; 256(2):352-63. PubMed ID: 8594202
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Camel lactoferrin, a transferrin-cum-lactoferrin: crystal structure of camel apolactoferrin at 2.6 A resolution and structural basis of its dual role.
    Khan JA; Kumar P; Paramasivam M; Yadav RS; Sahani MS; Sharma S; Srinivasan A; Singh TP
    J Mol Biol; 2001 Jun; 309(3):751-61. PubMed ID: 11397094
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Composition of pH-sensitive triad in C-lobe of human serum transferrin. Comparison to sequences of ovotransferrin and lactoferrin provides insight into functional differences in iron release.
    Halbrooks PJ; Giannetti AM; Klein JS; Björkman PJ; Larouche JR; Smith VC; MacGillivray RT; Everse SJ; Mason AB
    Biochemistry; 2005 Nov; 44(47):15451-60. PubMed ID: 16300393
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Ligand-induced conformational change in transferrins: crystal structure of the open form of the N-terminal half-molecule of human transferrin.
    Jeffrey PD; Bewley MC; MacGillivray RT; Mason AB; Woodworth RC; Baker EN
    Biochemistry; 1998 Oct; 37(40):13978-86. PubMed ID: 9760232
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structures of two mutants that probe the role in iron release of the dilysine pair in the N-lobe of human transferrin.
    Baker HM; Nurizzo D; Mason AB; Baker EN
    Acta Crystallogr D Biol Crystallogr; 2007 Mar; 63(Pt 3):408-14. PubMed ID: 17327678
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Ligand variation in the transferrin family: the crystal structure of the H249Q mutant of the human transferrin N-lobe as a model for iron binding in insect transferrins.
    Baker HM; Mason AB; He QY; MacGillivray RT; Baker EN
    Biochemistry; 2001 Oct; 40(39):11670-5. PubMed ID: 11570867
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Kinetic studies on the removal of iron and aluminum from recombinant and site-directed mutant N-lobe half transferrins.
    Li Y; Harris WR; Maxwell A; MacGillivray RT; Brown T
    Biochemistry; 1998 Oct; 37(40):14157-66. PubMed ID: 9760252
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mutation of arginine 121 in lactoferrin destabilizes iron binding by disruption of anion binding: crystal structures of R121S and R121E mutants.
    Faber HR; Baker CJ; Day CL; Tweedie JW; Baker EN
    Biochemistry; 1996 Nov; 35(46):14473-9. PubMed ID: 8931543
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Lactoferrin and iron: structural and dynamic aspects of binding and release.
    Baker HM; Baker EN
    Biometals; 2004 Jun; 17(3):209-16. PubMed ID: 15222467
    [TBL] [Abstract][Full Text] [Related]  

  • 14. X-ray structures of transferrins and related proteins.
    Mizutani K; Toyoda M; Mikami B
    Biochim Biophys Acta; 2012 Mar; 1820(3):203-11. PubMed ID: 21855609
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mutagenesis of the histidine ligand in human lactoferrin: iron binding properties and crystal structure of the histidine-253-->methionine mutant.
    Nicholson H; Anderson BF; Bland T; Shewry SC; Tweedie JW; Baker EN
    Biochemistry; 1997 Jan; 36(2):341-6. PubMed ID: 9003186
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structure of a domain-opened mutant (R121D) of the human lactoferrin N-lobe refined from a merohedrally twinned crystal form.
    Jameson GB; Anderson BF; Breyer WA; Day CL; Tweedie JW; Baker EN
    Acta Crystallogr D Biol Crystallogr; 2002 Jun; 58(Pt 6 Pt 2):955-62. PubMed ID: 12037297
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dual role of Lys206-Lys296 interaction in human transferrin N-lobe: iron-release trigger and anion-binding site.
    He QY; Mason AB; Tam BM; MacGillivray RT; Woodworth RC
    Biochemistry; 1999 Jul; 38(30):9704-11. PubMed ID: 10423249
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structure of the recombinant N-terminal lobe of human lactoferrin at 2.0 A resolution.
    Day CL; Anderson BF; Tweedie JW; Baker EN
    J Mol Biol; 1993 Aug; 232(4):1084-100. PubMed ID: 8371268
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mutations at the histidine 249 ligand profoundly alter the spectral and iron-binding properties of human serum transferrin N-lobe.
    He QY; Mason AB; Pakdaman R; Chasteen ND; Dixon BK; Tam BM; Nguyen V; MacGillivray RT; Woodworth RC
    Biochemistry; 2000 Feb; 39(6):1205-10. PubMed ID: 10684597
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structural and functional consequences of binding site mutations in transferrin: crystal structures of the Asp63Glu and Arg124Ala mutants of the N-lobe of human transferrin.
    Baker HM; He QY; Briggs SK; Mason AB; Baker EN
    Biochemistry; 2003 Jun; 42(23):7084-9. PubMed ID: 12795604
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.