These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

99 related articles for article (PubMed ID: 12455229)

  • 21. Synthesis and anti-human immunodeficiency virus type 1 (HIV-1) activity of 3-substituted derivatives of 3'-azido-3'-deoxythymidine (AZT), and inhibition of HIV-1 reverse transcriptase by their 5'-triphosphates.
    Kitade Y; Suzuki A; Hirota K; Maki Y; Nakane H; Ono K; Baba M; Shigeta S
    Chem Pharm Bull (Tokyo); 1992 Apr; 40(4):920-4. PubMed ID: 1381996
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Combination of drugs and drug-resistant reverse transcriptase results in a multiplicative increase of human immunodeficiency virus type 1 mutant frequencies.
    Mansky LM; Pearl DK; Gajary LC
    J Virol; 2002 Sep; 76(18):9253-9. PubMed ID: 12186909
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Rapid in vitro selection of human immunodeficiency virus type 1 resistant to 3'-thiacytidine inhibitors due to a mutation in the YMDD region of reverse transcriptase.
    Tisdale M; Kemp SD; Parry NR; Larder BA
    Proc Natl Acad Sci U S A; 1993 Jun; 90(12):5653-6. PubMed ID: 7685907
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Nucleoside analog resistance caused by insertions in the fingers of human immunodeficiency virus type 1 reverse transcriptase involves ATP-mediated excision.
    Boyer PL; Sarafianos SG; Arnold E; Hughes SH
    J Virol; 2002 Sep; 76(18):9143-51. PubMed ID: 12186898
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Design, synthesis, and anti-HIV-1 activity of 1-aromatic methyl-substituted 3-(3,5-dimethylbenzyl)uracil and N-3,5-dimethylbenzyl-substituted urea derivatives.
    Sakakibara N; Baba M; Okamoto M; Toyama M; Demizu Y; Misawa T; Kurihara M; Irie K; Kato Y; Maruyama T
    Antivir Chem Chemother; 2015 Feb; 24(1):3-18. PubMed ID: 26149262
    [TBL] [Abstract][Full Text] [Related]  

  • 26. 2'-Deoxy-4'-C-ethynyl-2-fluoroadenosine: a nucleoside reverse transcriptase inhibitor with highly potent activity against all HIV-1 strains, favorable toxic profiles and stability in plasma.
    Ohrui H; Kohgo S; Hayakawa H; Kodama E; Matsuoka M; Nakata T; Mitsuya H
    Nucleic Acids Symp Ser (Oxf); 2006; (50):1-2. PubMed ID: 17150787
    [TBL] [Abstract][Full Text] [Related]  

  • 27. N-[2-(1-cyclohexenyl)ethyl]-N'-[2-(5-bromopyridyl)]-thiourea and N'-[2-(1-cyclohexenyl)ethyl]-N'-[2-(5-chloropyridyl)]-thiourea as potent inhibitors of multidrug-resistant human immunodeficiency virus-1.
    Uckun FM; Mao C; Pendergrass S; Maher D; Zhu D; Tuel-Ahlgren L; Venkatachalam TK
    Bioorg Med Chem Lett; 1999 Sep; 9(18):2721-6. PubMed ID: 10509923
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Synthesis and biological activity of novel nonnucleoside inhibitors of HIV-1 reverse transcriptase. 2-Aryl-substituted benzimidazoles.
    Roth T; Morningstar ML; Boyer PL; Hughes SH; Buckheit RW; Michejda CJ
    J Med Chem; 1997 Dec; 40(26):4199-207. PubMed ID: 9435891
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Synthesis and antiviral activity of several 2,5'-anhydro analogues of 3'-azido-3'-deoxythymidine, 3'-azido-2',3'-dideoxyuridine, 3'-azido-2',3'-dideoxy-5-halouridines, and 3'-deoxythymidine against human immunodeficiency virus and Rauscher-murine leukemia virus.
    Lin TS; Shen ZY; August EM; Brankovan V; Yang H; Ghazzouli I; Prusoff WH
    J Med Chem; 1989 Aug; 32(8):1891-5. PubMed ID: 2754712
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Synthesis, antiviral activity, and mechanism of drug resistance of D- and L-2',3'-didehydro-2',3'-dideoxy-2'-fluorocarbocyclic nucleosides.
    Wang J; Jin Y; Rapp KL; Bennett M; Schinazi RF; Chu CK
    J Med Chem; 2005 Jun; 48(11):3736-48. PubMed ID: 15916425
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Human immunodeficiency virus mutagenesis during antiviral therapy: impact of drug-resistant reverse transcriptase and nucleoside and nonnucleoside reverse transcriptase inhibitors on human immunodeficiency virus type 1 mutation frequencies.
    Chen R; Yokoyama M; Sato H; Reilly C; Mansky LM
    J Virol; 2005 Sep; 79(18):12045-57. PubMed ID: 16140780
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Structure-based design of non-nucleoside reverse transcriptase inhibitors of drug-resistant human immunodeficiency virus.
    Mao C; Sudbeck EA; Venkatachalam TK; Uckun FM
    Antivir Chem Chemother; 1999 Sep; 10(5):233-40. PubMed ID: 10574178
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Anti-AIDS agents. 60. Substituted 3'R,4'R-di-O-(-)-camphanoyl-2',2'-dimethyldihydropyrano[2,3-f]chromone (DCP) analogues as potent anti-HIV agents.
    Yu D; Chen CH; Brossi A; Lee KH
    J Med Chem; 2004 Jul; 47(16):4072-82. PubMed ID: 15267246
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Anti-HIV type 1 activity of 3'-fluoro-3'-deoxythymidine for several different multidrug-resistant mutants.
    Kim EY; Vrang L; Oberg B; Merigan TC
    AIDS Res Hum Retroviruses; 2001 Mar; 17(5):401-7. PubMed ID: 11282008
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Combining New Non-Nucleoside Reverse Transcriptase Inhibitors (RTIs) with AZT Results in Strong Synergism against Multi-RTI-Resistant HIV-1 Strains.
    Yu F; Li W; Wang L; Dai Y; Lu X; Wang Q; Xie L; Jiang S
    Molecules; 2018 Jul; 23(7):. PubMed ID: 30004408
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Thiated derivatives of 2',3'-dideoxy-3'-fluorothymidine: synthesis, in vitro anti-HIV-1 activity and interaction with recombinant drug resistant HIV-1 reverse transcriptase forms.
    Miazga A; Hamy F; Louvel S; Klimkait T; Pietrusiewicz Z; Kurzyńska-Kokorniak A; Figlerowicz M; Wińska P; Kulikowski T
    Antiviral Res; 2011 Oct; 92(1):57-63. PubMed ID: 21683097
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Effects of beta-L-3'-azido-3'-deoxythymidine 5'-triphosphate on host and viral DNA polymerases.
    Faraj A; El Alaoui AM; Gosselin G; Imbach JL; Morrow C; Sommadossi JP
    Antiviral Res; 2000 Aug; 47(2):97-102. PubMed ID: 10996397
    [TBL] [Abstract][Full Text] [Related]  

  • 38. In vitro anti-human immunodeficiency virus activities of Z- and E-methylenecyclopropane nucleoside analogues and their phosphoro-L-alaninate diesters.
    Uchida H; Kodama EN; Yoshimura K; Maeda Y; Kosalaraksa P; Maroun V; Qiu YL; Zemlicka J; Mitsuya H
    Antimicrob Agents Chemother; 1999 Jun; 43(6):1487-90. PubMed ID: 10348777
    [TBL] [Abstract][Full Text] [Related]  

  • 39. The HEPT Analogue WPR-6 Is Active against a Broad Spectrum of Nonnucleoside Reverse Transcriptase Drug-Resistant HIV-1 Strains of Different Serotypes.
    Xu W; Zhao J; Sun J; Yin Q; Wang Y; Jiao Y; Liu J; Jiang S; Shao Y; Wang X; Ma L
    Antimicrob Agents Chemother; 2015 Aug; 59(8):4882-8. PubMed ID: 26055365
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Anti-human immunodeficiency virus type 1 activity and resistance profile of 2',3'-didehydro-3'-deoxy-4'-ethynylthymidine in vitro.
    Nitanda T; Wang X; Kumamoto H; Haraguchi K; Tanaka H; Cheng YC; Baba M
    Antimicrob Agents Chemother; 2005 Aug; 49(8):3355-60. PubMed ID: 16048947
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 5.