263 related articles for article (PubMed ID: 12459277)
1. Characterization of the bovine IkappaB kinases (IKK)alpha and IKKbeta, the regulatory subunit NEMO and their substrate IkappaBalpha.
Rottenberg S; Schmuckli-Maurer J; Grimm S; Heussler VT; Dobbelaere DA
Gene; 2002 Oct; 299(1-2):293-300. PubMed ID: 12459277
[TBL] [Abstract][Full Text] [Related]
2. Regulation and function of IKK and IKK-related kinases.
Häcker H; Karin M
Sci STKE; 2006 Oct; 2006(357):re13. PubMed ID: 17047224
[TBL] [Abstract][Full Text] [Related]
3. IKKalpha, IKKbeta, and NEMO/IKKgamma are each required for the NF-kappa B-mediated inflammatory response program.
Li X; Massa PE; Hanidu A; Peet GW; Aro P; Savitt A; Mische S; Li J; Marcu KB
J Biol Chem; 2002 Nov; 277(47):45129-40. PubMed ID: 12221085
[TBL] [Abstract][Full Text] [Related]
4. NF-kappaB activation during Rickettsia rickettsii infection of endothelial cells involves the activation of catalytic IkappaB kinases IKKalpha and IKKbeta and phosphorylation-proteolysis of the inhibitor protein IkappaBalpha.
Clifton DR; Rydkina E; Freeman RS; Sahni SK
Infect Immun; 2005 Jan; 73(1):155-65. PubMed ID: 15618150
[TBL] [Abstract][Full Text] [Related]
5. Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected].
Wu CJ; Conze DB; Li T; Srinivasula SM; Ashwell JD
Nat Cell Biol; 2006 Apr; 8(4):398-406. PubMed ID: 16547522
[TBL] [Abstract][Full Text] [Related]
6. Regulation of I(kappa)B kinase complex by phosphorylation of (gamma)-binding domain of I(kappa)B kinase (beta) by Polo-like kinase 1.
Higashimoto T; Chan N; Lee YK; Zandi E
J Biol Chem; 2008 Dec; 283(51):35354-67. PubMed ID: 18957422
[TBL] [Abstract][Full Text] [Related]
7. Interleukin-1-induced NF-kappaB activation is NEMO-dependent but does not require IKKbeta.
Solt LA; Madge LA; Orange JS; May MJ
J Biol Chem; 2007 Mar; 282(12):8724-33. PubMed ID: 17244613
[TBL] [Abstract][Full Text] [Related]
8. Inhibition of IKK down-regulates antigen + IgE-induced TNF production by mast cells: a role for the IKK-IkappaB-NF-kappaB pathway in IgE-dependent mast cell activation.
Peng Y; Power MR; Li B; Lin TJ
J Leukoc Biol; 2005 Jun; 77(6):975-83. PubMed ID: 15784689
[TBL] [Abstract][Full Text] [Related]
9. The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis.
Li ZW; Chu W; Hu Y; Delhase M; Deerinck T; Ellisman M; Johnson R; Karin M
J Exp Med; 1999 Jun; 189(11):1839-45. PubMed ID: 10359587
[TBL] [Abstract][Full Text] [Related]
10. Phosphorylation of serine 68 in the IkappaB kinase (IKK)-binding domain of NEMO interferes with the structure of the IKK complex and tumor necrosis factor-alpha-induced NF-kappaB activity.
Palkowitsch L; Leidner J; Ghosh S; Marienfeld RB
J Biol Chem; 2008 Jan; 283(1):76-86. PubMed ID: 17977820
[TBL] [Abstract][Full Text] [Related]
11. Novel non-peptide small molecules preventing IKKβ/NEMO association inhibit NF-κB activation in LPS-stimulated J774 macrophages.
De Falco F; Di Giovanni C; Cerchia C; De Stefano D; Capuozzo A; Irace C; Iuvone T; Santamaria R; Carnuccio R; Lavecchia A
Biochem Pharmacol; 2016 Mar; 104():83-94. PubMed ID: 26776306
[TBL] [Abstract][Full Text] [Related]
12. The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation.
Zandi E; Rothwarf DM; Delhase M; Hayakawa M; Karin M
Cell; 1997 Oct; 91(2):243-52. PubMed ID: 9346241
[TBL] [Abstract][Full Text] [Related]
13. NEMO-binding domains of both IKKalpha and IKKbeta regulate IkappaB kinase complex assembly and classical NF-kappaB activation.
Solt LA; Madge LA; May MJ
J Biol Chem; 2009 Oct; 284(40):27596-608. PubMed ID: 19666475
[TBL] [Abstract][Full Text] [Related]
14. Regulation of Ikappa B kinase (IKK)gamma /NEMO function by IKKbeta -mediated phosphorylation.
Prajapati S; Gaynor RB
J Biol Chem; 2002 Jul; 277(27):24331-9. PubMed ID: 11971901
[TBL] [Abstract][Full Text] [Related]
15. IKKgamma serves as a docking subunit of the IkappaB kinase (IKK) and mediates interaction of IKK with the human T-cell leukemia virus Tax protein.
Harhaj EW; Sun SC
J Biol Chem; 1999 Aug; 274(33):22911-4. PubMed ID: 10438454
[TBL] [Abstract][Full Text] [Related]
16. Recombinant IkappaB kinases alpha and beta are direct kinases of Ikappa Balpha.
Li J; Peet GW; Pullen SS; Schembri-King J; Warren TC; Marcu KB; Kehry MR; Barton R; Jakes S
J Biol Chem; 1998 Nov; 273(46):30736-41. PubMed ID: 9804849
[TBL] [Abstract][Full Text] [Related]
17. Sites on FIP-3 (NEMO/IKKgamma) essential for its phosphorylation and NF-kappaB modulating activity.
Tarassishin L; Horwitz MS
Biochem Biophys Res Commun; 2001 Jul; 285(2):555-60. PubMed ID: 11444880
[TBL] [Abstract][Full Text] [Related]
18. The NF-kappaB pathway in human endometrium and first trimester decidua.
King AE; Critchley HO; Kelly RW
Mol Hum Reprod; 2001 Feb; 7(2):175-83. PubMed ID: 11160844
[TBL] [Abstract][Full Text] [Related]
19. Functional isoforms of IkappaB kinase alpha (IKKalpha) lacking leucine zipper and helix-loop-helix domains reveal that IKKalpha and IKKbeta have different activation requirements.
McKenzie FR; Connelly MA; Balzarano D; Müller JR; Geleziunas R; Marcu KB
Mol Cell Biol; 2000 Apr; 20(8):2635-49. PubMed ID: 10733566
[TBL] [Abstract][Full Text] [Related]
20. Tetrameric oligomerization of IkappaB kinase gamma (IKKgamma) is obligatory for IKK complex activity and NF-kappaB activation.
Tegethoff S; Behlke J; Scheidereit C
Mol Cell Biol; 2003 Mar; 23(6):2029-41. PubMed ID: 12612076
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
