BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

354 related articles for article (PubMed ID: 12459440)

  • 1. Two-step error-prone bypass of the (+)- and (-)-trans-anti-BPDE-N2-dG adducts by human DNA polymerases eta and kappa.
    Zhang Y; Wu X; Guo D; Rechkoblit O; Geacintov NE; Wang Z
    Mutat Res; 2002 Dec; 510(1-2):23-35. PubMed ID: 12459440
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Poleta, Polzeta and Rev1 together are required for G to T transversion mutations induced by the (+)- and (-)-trans-anti-BPDE-N2-dG DNA adducts in yeast cells.
    Zhao B; Wang J; Geacintov NE; Wang Z
    Nucleic Acids Res; 2006; 34(2):417-25. PubMed ID: 16415180
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Activities of human DNA polymerase kappa in response to the major benzo[a]pyrene DNA adduct: error-free lesion bypass and extension synthesis from opposite the lesion.
    Zhang Y; Wu X; Guo D; Rechkoblit O; Wang Z
    DNA Repair (Amst); 2002 Jul; 1(7):559-69. PubMed ID: 12509229
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Translesion synthesis by human DNA polymerase kappa on a DNA template containing a single stereoisomer of dG-(+)- or dG-(-)-anti-N(2)-BPDE (7,8-dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene).
    Suzuki N; Ohashi E; Kolbanovskiy A; Geacintov NE; Grollman AP; Ohmori H; Shibutani S
    Biochemistry; 2002 May; 41(19):6100-6. PubMed ID: 11994005
    [TBL] [Abstract][Full Text] [Related]  

  • 5. trans-Lesion synthesis past bulky benzo[a]pyrene diol epoxide N2-dG and N6-dA lesions catalyzed by DNA bypass polymerases.
    Rechkoblit O; Zhang Y; Guo D; Wang Z; Amin S; Krzeminsky J; Louneva N; Geacintov NE
    J Biol Chem; 2002 Aug; 277(34):30488-94. PubMed ID: 12063247
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Base pair conformation-dependent excision of benzo[a]pyrene diol epoxide-guanine adducts by human nucleotide excision repair enzymes.
    Hess MT; Gunz D; Luneva N; Geacintov NE; Naegeli H
    Mol Cell Biol; 1997 Dec; 17(12):7069-76. PubMed ID: 9372938
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Phenylalanine 171 is a molecular brake for translesion synthesis across benzo[a]pyrene-guanine adducts by human DNA polymerase kappa.
    Sassa A; Niimi N; Fujimoto H; Katafuchi A; Grúz P; Yasui M; Gupta RC; Johnson F; Ohta T; Nohmi T
    Mutat Res; 2011 Jan; 718(1-2):10-7. PubMed ID: 21078407
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Effects of the N terminus of mouse DNA polymerase κ on the bypass of a guanine-benzo[a]pyrenyl adduct.
    Liu Y; Ma X; Guo C
    J Biochem; 2016 Apr; 159(4):471-9. PubMed ID: 26634445
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mutagenesis of benzo[a]pyrene diol epoxide in yeast: requirement for DNA polymerase zeta and involvement of DNA polymerase eta.
    Xie Z; Braithwaite E; Guo D; Zhao B; Geacintov NE; Wang Z
    Biochemistry; 2003 Sep; 42(38):11253-62. PubMed ID: 14503875
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Extending the understanding of mutagenicity: structural insights into primer-extension past a benzo[a]pyrene diol epoxide-DNA adduct.
    Perlow RA; Broyde S
    J Mol Biol; 2003 Apr; 327(4):797-818. PubMed ID: 12654264
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Human DNA polymerases catalyze lesion bypass across benzo[a]pyrene-derived DNA adduct clustered with an abasic site.
    Starostenko LV; Rechkunova NI; Lebedeva NA; Kolbanovskiy A; Geacintov NE; Lavrik OI
    DNA Repair (Amst); 2014 Dec; 24():1-9. PubMed ID: 25460917
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effects of base sequence context on translesion synthesis past a bulky (+)-trans-anti-B[a]P-N2-dG lesion catalyzed by the Y-family polymerase pol kappa.
    Huang X; Kolbanovskiy A; Wu X; Zhang Y; Wang Z; Zhuang P; Amin S; Geacintov NE
    Biochemistry; 2003 Mar; 42(8):2456-66. PubMed ID: 12600213
    [TBL] [Abstract][Full Text] [Related]  

  • 13. In vivo evidence that phenylalanine 171 acts as a molecular brake for translesion DNA synthesis across benzo[a]pyrene DNA adducts by human DNA polymerase κ.
    Sassa A; Suzuki T; Kanemaru Y; Niimi N; Fujimoto H; Katafuchi A; Grúz P; Yasui M; Gupta RC; Johnson F; Ohta T; Honma M; Adachi N; Nohmi T
    DNA Repair (Amst); 2014 Mar; 15():21-8. PubMed ID: 24461735
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Fidelity of translesional synthesis past benzo[a]pyrene diol epoxide-2'-deoxyguanosine DNA adducts: marked effects of host cell, sequence context, and chirality.
    Moriya M; Spiegel S; Fernandes A; Amin S; Liu T; Geacintov N; Grollman AP
    Biochemistry; 1996 Dec; 35(51):16646-51. PubMed ID: 8988000
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mutagenic potential of benzo[a]pyrene-derived DNA adducts positioned in codon 273 of the human P53 gene.
    Dong H; Bonala RR; Suzuki N; Johnson F; Grollman AP; Shibutani S
    Biochemistry; 2004 Dec; 43(50):15922-8. PubMed ID: 15595848
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Spectral differentiation and immunoaffinity capillary electrophoresis separation of enantiomeric benzo(a)pyrene diol epoxide-derived DNA adducts.
    Miksa B; Chinnappan R; Dang NC; Reppert M; Matter B; Tretyakova N; Grubor NM; Jankowiak R
    Chem Res Toxicol; 2007 Aug; 20(8):1192-9. PubMed ID: 17630708
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Translesional synthesis on a DNA template containing a single stereoisomer of dG-(+)- or dG-(-)-anti-BPDE (7,8-dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene).
    Shibutani S; Margulis LA; Geacintov NE; Grollman AP
    Biochemistry; 1993 Jul; 32(29):7531-41. PubMed ID: 8338850
    [TBL] [Abstract][Full Text] [Related]  

  • 18. DNA adducts from a tumorigenic metabolite of benzo[a]pyrene block human RNA polymerase II elongation in a sequence- and stereochemistry-dependent manner.
    Perlow RA; Kolbanovskii A; Hingerty BE; Geacintov NE; Broyde S; Scicchitano DA
    J Mol Biol; 2002 Aug; 321(1):29-47. PubMed ID: 12139931
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Evading the proofreading machinery of a replicative DNA polymerase: induction of a mutation by an environmental carcinogen.
    Perlow RA; Broyde S
    J Mol Biol; 2001 Jun; 309(2):519-36. PubMed ID: 11371169
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Error-free and error-prone lesion bypass by human DNA polymerase kappa in vitro.
    Zhang Y; Yuan F; Wu X; Wang M; Rechkoblit O; Taylor JS; Geacintov NE; Wang Z
    Nucleic Acids Res; 2000 Nov; 28(21):4138-46. PubMed ID: 11058110
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.