BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

258 related articles for article (PubMed ID: 12459484)

  • 1. Integrin-nucleated Toll-like receptor (TLR) dimerization reveals subcellular targeting of TLRs and distinct mechanisms of TLR4 activation and signaling.
    Zhang H; Tay PN; Cao W; Li W; Lu J
    FEBS Lett; 2002 Dec; 532(1-2):171-6. PubMed ID: 12459484
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction.
    Fitzgerald KA; Palsson-McDermott EM; Bowie AG; Jefferies CA; Mansell AS; Brady G; Brint E; Dunne A; Gray P; Harte MT; McMurray D; Smith DE; Sims JE; Bird TA; O'Neill LA
    Nature; 2001 Sep; 413(6851):78-83. PubMed ID: 11544529
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cooperation of Toll-like receptor 2 and 6 for cellular activation by soluble tuberculosis factor and Borrelia burgdorferi outer surface protein A lipoprotein: role of Toll-interacting protein and IL-1 receptor signaling molecules in Toll-like receptor 2 signaling.
    Bulut Y; Faure E; Thomas L; Equils O; Arditi M
    J Immunol; 2001 Jul; 167(2):987-94. PubMed ID: 11441107
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Heat-killed Brucella abortus induces TNF and IL-12p40 by distinct MyD88-dependent pathways: TNF, unlike IL-12p40 secretion, is Toll-like receptor 2 dependent.
    Huang LY; Aliberti J; Leifer CA; Segal DM; Sher A; Golenbock DT; Golding B
    J Immunol; 2003 Aug; 171(3):1441-6. PubMed ID: 12874236
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Specific inhibition of MyD88-independent signaling pathways of TLR3 and TLR4 by resveratrol: molecular targets are TBK1 and RIP1 in TRIF complex.
    Youn HS; Lee JY; Fitzgerald KA; Young HA; Akira S; Hwang DH
    J Immunol; 2005 Sep; 175(5):3339-46. PubMed ID: 16116226
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structural complementarity of Toll/interleukin-1 receptor domains in Toll-like receptors and the adaptors Mal and MyD88.
    Dunne A; Ejdeback M; Ludidi PL; O'Neill LA; Gay NJ
    J Biol Chem; 2003 Oct; 278(42):41443-51. PubMed ID: 12888566
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Intracellular bacterial infection-induced IFN-gamma is critically but not solely dependent on Toll-like receptor 4-myeloid differentiation factor 88-IFN-alpha beta-STAT1 signaling.
    Rothfuchs AG; Trumstedt C; Wigzell H; Rottenberg ME
    J Immunol; 2004 May; 172(10):6345-53. PubMed ID: 15128825
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4.
    Yamamoto M; Sato S; Hemmi H; Sanjo H; Uematsu S; Kaisho T; Hoshino K; Takeuchi O; Kobayashi M; Fujita T; Takeda K; Akira S
    Nature; 2002 Nov; 420(6913):324-9. PubMed ID: 12447441
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway.
    Yamamoto M; Sato S; Hemmi H; Hoshino K; Kaisho T; Sanjo H; Takeuchi O; Sugiyama M; Okabe M; Takeda K; Akira S
    Science; 2003 Aug; 301(5633):640-3. PubMed ID: 12855817
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors.
    Horng T; Barton GM; Flavell RA; Medzhitov R
    Nature; 2002 Nov; 420(6913):329-33. PubMed ID: 12447442
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ligand-regulated chimeric receptor approach reveals distinctive subcellular localization and signaling properties of the Toll-like receptors.
    Nishiya T; DeFranco AL
    J Biol Chem; 2004 Apr; 279(18):19008-17. PubMed ID: 14976215
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cellular activation, phagocytosis, and bactericidal activity against group B streptococcus involve parallel myeloid differentiation factor 88-dependent and independent signaling pathways.
    Henneke P; Takeuchi O; Malley R; Lien E; Ingalls RR; Freeman MW; Mayadas T; Nizet V; Akira S; Kasper DL; Golenbock DT
    J Immunol; 2002 Oct; 169(7):3970-7. PubMed ID: 12244198
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Toll-like receptor 4 and Toll-IL-1 receptor domain-containing adapter protein (TIRAP)/myeloid differentiation protein 88 adapter-like (Mal) contribute to maximal IL-6 expression in macrophages.
    Schilling D; Thomas K; Nixdorff K; Vogel SN; Fenton MJ
    J Immunol; 2002 Nov; 169(10):5874-80. PubMed ID: 12421970
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cell activation by Porphyromonas gingivalis lipid A molecule through Toll-like receptor 4- and myeloid differentiation factor 88-dependent signaling pathway.
    Ogawa T; Asai Y; Hashimoto M; Takeuchi O; Kurita T; Yoshikai Y; Miyake K; Akira S
    Int Immunol; 2002 Nov; 14(11):1325-32. PubMed ID: 12407023
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cytoplasmic domain-mediated dimerizations of toll-like receptor 4 observed by beta-lactamase enzyme fragment complementation.
    Lee HK; Dunzendorfer S; Tobias PS
    J Biol Chem; 2004 Mar; 279(11):10564-74. PubMed ID: 14699116
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Micrococci and peptidoglycan activate TLR2-->MyD88-->IRAK-->TRAF-->NIK-->IKK-->NF-kappaB signal transduction pathway that induces transcription of interleukin-8.
    Wang Q; Dziarski R; Kirschning CJ; Muzio M; Gupta D
    Infect Immun; 2001 Apr; 69(4):2270-6. PubMed ID: 11254583
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Contribution of Toll-like receptor/myeloid differentiation factor 88 signaling to murine liver regeneration.
    Seki E; Tsutsui H; Iimuro Y; Naka T; Son G; Akira S; Kishimoto T; Nakanishi K; Fujimoto J
    Hepatology; 2005 Mar; 41(3):443-50. PubMed ID: 15723296
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Chlamydial heat shock protein 60 activates macrophages and endothelial cells through Toll-like receptor 4 and MD2 in a MyD88-dependent pathway.
    Bulut Y; Faure E; Thomas L; Karahashi H; Michelsen KS; Equils O; Morrison SG; Morrison RP; Arditi M
    J Immunol; 2002 Feb; 168(3):1435-40. PubMed ID: 11801686
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cutting edge: a novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling.
    Yamamoto M; Sato S; Mori K; Hoshino K; Takeuchi O; Takeda K; Akira S
    J Immunol; 2002 Dec; 169(12):6668-72. PubMed ID: 12471095
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cutting edge: TNFR-associated factor (TRAF) 6 is essential for MyD88-dependent pathway but not toll/IL-1 receptor domain-containing adaptor-inducing IFN-beta (TRIF)-dependent pathway in TLR signaling.
    Gohda J; Matsumura T; Inoue J
    J Immunol; 2004 Sep; 173(5):2913-7. PubMed ID: 15322147
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.