BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

341 related articles for article (PubMed ID: 12460905)

  • 1. Antitumor effect of the human immunodeficiency virus protease inhibitor ritonavir: induction of tumor-cell apoptosis associated with perturbation of proteasomal proteolysis.
    Gaedicke S; Firat-Geier E; Constantiniu O; Lucchiari-Hartz M; Freudenberg M; Galanos C; Niedermann G
    Cancer Res; 2002 Dec; 62(23):6901-8. PubMed ID: 12460905
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The human immunodeficiency virus (HIV)-1 protease inhibitor saquinavir inhibits proteasome function and causes apoptosis and radiosensitization in non-HIV-associated human cancer cells.
    Pajonk F; Himmelsbach J; Riess K; Sommer A; McBride WH
    Cancer Res; 2002 Sep; 62(18):5230-5. PubMed ID: 12234989
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mechanisms of proteasome inhibitor PS-341-induced G(2)-M-phase arrest and apoptosis in human non-small cell lung cancer cell lines.
    Ling YH; Liebes L; Jiang JD; Holland JF; Elliott PJ; Adams J; Muggia FM; Perez-Soler R
    Clin Cancer Res; 2003 Mar; 9(3):1145-54. PubMed ID: 12631620
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Tumor growth inhibition induced in a murine model of human Burkitt's lymphoma by a proteasome inhibitor.
    Orlowski RZ; Eswara JR; Lafond-Walker A; Grever MR; Orlowski M; Dang CV
    Cancer Res; 1998 Oct; 58(19):4342-8. PubMed ID: 9766662
    [TBL] [Abstract][Full Text] [Related]  

  • 5. p27Kip1 accumulation by inhibition of proteasome function induces apoptosis in oral squamous cell carcinoma cells.
    Kudo Y; Takata T; Ogawa I; Kaneda T; Sato S; Takekoshi T; Zhao M; Miyauchi M; Nikai H
    Clin Cancer Res; 2000 Mar; 6(3):916-23. PubMed ID: 10741716
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Increased expression and altered subunit composition of proteasomes induced by continuous proteasome inhibition establish apoptosis resistance and hyperproliferation of Burkitt lymphoma cells.
    Fuchs D; Berges C; Opelz G; Daniel V; Naujokat C
    J Cell Biochem; 2008 Jan; 103(1):270-83. PubMed ID: 17516511
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Role of p53 in cell cycle regulation and apoptosis following exposure to proteasome inhibitors.
    Chen F; Chang D; Goh M; Klibanov SA; Ljungman M
    Cell Growth Differ; 2000 May; 11(5):239-46. PubMed ID: 10845424
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Differential sensitivity of breast cancer and melanoma cells to proteasome inhibitor Velcade.
    Yerlikaya A; Erin N
    Int J Mol Med; 2008 Dec; 22(6):817-23. PubMed ID: 19020781
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Evaluation of antitumoral properties of the protease inhibitor indinavir in a murine model of hepatocarcinoma.
    Esposito V; Palescandolo E; Spugnini EP; Montesarchio V; De Luca A; Cardillo I; Cortese G; Baldi A; Chirianni A
    Clin Cancer Res; 2006 Apr; 12(8):2634-9. PubMed ID: 16638877
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Nelfinavir induces liposarcoma apoptosis and cell cycle arrest by upregulating sterol regulatory element binding protein-1.
    Chow WA; Guo S; Valdes-Albini F
    Anticancer Drugs; 2006 Sep; 17(8):891-903. PubMed ID: 16940799
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibitors of transcription, proteasome inhibitors, and DNA-damaging drugs differentially affect feedback of p53 degradation.
    An WG; Chuman Y; Fojo T; Blagosklonny MV
    Exp Cell Res; 1998 Oct; 244(1):54-60. PubMed ID: 9770348
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Clioquinol, a therapeutic agent for Alzheimer's disease, has proteasome-inhibitory, androgen receptor-suppressing, apoptosis-inducing, and antitumor activities in human prostate cancer cells and xenografts.
    Chen D; Cui QC; Yang H; Barrea RA; Sarkar FH; Sheng S; Yan B; Reddy GP; Dou QP
    Cancer Res; 2007 Feb; 67(4):1636-44. PubMed ID: 17308104
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Lactacystin, a proteasome inhibitor, potentiates the apoptotic effect of parthenolide, an inhibitor of NFkappaB activation, on drug-resistant mouse leukemia L1210 cells.
    Cory AH; Cory JG
    Anticancer Res; 2002; 22(6C):3805-9. PubMed ID: 12552998
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Tannic acid potently inhibits tumor cell proteasome activity, increases p27 and Bax expression, and induces G1 arrest and apoptosis.
    Nam S; Smith DM; Dou QP
    Cancer Epidemiol Biomarkers Prev; 2001 Oct; 10(10):1083-8. PubMed ID: 11588135
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Ritonavir interacts with bortezomib to enhance protein ubiquitination and histone acetylation synergistically in renal cancer cells.
    Sato A; Asano T; Ito K; Asano T
    Urology; 2012 Apr; 79(4):966.e13-21. PubMed ID: 22296623
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibition of proteasome activity by various fruits and vegetables is associated with cancer cell death.
    Chen MS; Chen D; Dou QP
    In Vivo; 2004; 18(1):73-80. PubMed ID: 15011755
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pyrrolidine dithiocarbamate and zinc inhibit proteasome-dependent proteolysis.
    Kim I; Kim CH; Kim JH; Lee J; Choi JJ; Chen ZA; Lee MG; Chung KC; Hsu CY; Ahn YS
    Exp Cell Res; 2004 Aug; 298(1):229-38. PubMed ID: 15242777
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Differential impairment of 20S and 26S proteasome activities in human hematopoietic K562 cells during oxidative stress.
    Reinheckel T; Ullrich O; Sitte N; Grune T
    Arch Biochem Biophys; 2000 May; 377(1):65-8. PubMed ID: 10775442
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Voreloxin, formerly SNS-595, has potent activity against a broad panel of cancer cell lines and in vivo tumor models.
    Hoch U; Lynch J; Sato Y; Kashimoto S; Kajikawa F; Furutani Y; Silverman JA
    Cancer Chemother Pharmacol; 2009 Jun; 64(1):53-65. PubMed ID: 18931998
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Syrbactin class proteasome inhibitor-induced apoptosis and autophagy occurs in association with p53 accumulation and Akt/PKB activation in neuroblastoma.
    Archer CR; Koomoa DL; Mitsunaga EM; Clerc J; Shimizu M; Kaiser M; Schellenberg B; Dudler R; Bachmann AS
    Biochem Pharmacol; 2010 Jul; 80(2):170-8. PubMed ID: 20362557
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.