BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

258 related articles for article (PubMed ID: 12460926)

  • 1. AML-associated translocation products block vitamin D(3)-induced differentiation by sequestering the vitamin D(3) receptor.
    Puccetti E; Obradovic D; Beissert T; Bianchini A; Washburn B; Chiaradonna F; Boehrer S; Hoelzer D; Ottmann OG; Pelicci PG; Nervi C; Ruthardt M
    Cancer Res; 2002 Dec; 62(23):7050-8. PubMed ID: 12460926
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Fusion proteins of the retinoic acid receptor-alpha recruit histone deacetylase in promyelocytic leukaemia.
    Grignani F; De Matteis S; Nervi C; Tomassoni L; Gelmetti V; Cioce M; Fanelli M; Ruthardt M; Ferrara FF; Zamir I; Seiser C; Grignani F; Lazar MA; Minucci S; Pelicci PG
    Nature; 1998 Feb; 391(6669):815-8. PubMed ID: 9486655
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Opposite effects of the acute promyelocytic leukemia PML-retinoic acid receptor alpha (RAR alpha) and PLZF-RAR alpha fusion proteins on retinoic acid signalling.
    Ruthardt M; Testa U; Nervi C; Ferrucci PF; Grignani F; Puccetti E; Grignani F; Peschle C; Pelicci PG
    Mol Cell Biol; 1997 Aug; 17(8):4859-69. PubMed ID: 9234742
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The integrity of the charged pocket in the BTB/POZ domain is essential for the phenotype induced by the leukemia-associated t(11;17) fusion protein PLZF/RARalpha.
    Puccetti E; Zheng X; Brambilla D; Seshire A; Beissert T; Boehrer S; Nürnberger H; Hoelzer D; Ottmann OG; Nervi C; Ruthardt M
    Cancer Res; 2005 Jul; 65(14):6080-8. PubMed ID: 16024608
    [TBL] [Abstract][Full Text] [Related]  

  • 5. PML-RARalpha and AML1-ETO translocations are rarely associated with methylation of the RARbeta2 promoter.
    Tabe Y; Konopleva M; Kondo Y; Contractor R; Jin L; Ruvolo V; Tsutsumi-Ishii Y; Miyake K; Miyake N; Ohsaka A; Nagaoka I; Issa JP; Andreeff M
    Ann Hematol; 2006 Oct; 85(10):689-704. PubMed ID: 16832676
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Induction of a functional vitamin D receptor in all-trans-retinoic acid-induced monocytic differentiation of M2-type leukemic blast cells.
    Manfredini R; Trevisan F; Grande A; Tagliafico E; Montanari M; Lemoli R; Visani G; Tura S; Ferrari S; Ferrari S
    Cancer Res; 1999 Aug; 59(15):3803-11. PubMed ID: 10446999
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Targeting fusion protein/corepressor contact restores differentiation response in leukemia cells.
    Racanicchi S; Maccherani C; Liberatore C; Billi M; Gelmetti V; Panigada M; Rizzo G; Nervi C; Grignani F
    EMBO J; 2005 Mar; 24(6):1232-42. PubMed ID: 15729358
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Down-stream regions of the POZ-domain influence the interaction of the t(11;17)-associated PLZF/RARalpha fusion protein with the histone-deacetylase recruiting co-repressor complex.
    Puccetti E; Sennewald B; Fosca-Ferrara F; Boehrer S; Bianchini A; Hoelzer D; Ottmann OG; Nervi C; Ruthardt M
    Hematol J; 2001; 2(6):385-92. PubMed ID: 11920278
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Heterochromatic gene repression of the retinoic acid pathway in acute myeloid leukemia.
    Fazi F; Zardo G; Gelmetti V; Travaglini L; Ciolfi A; Di Croce L; Rosa A; Bozzoni I; Grignani F; Lo-Coco F; Pelicci PG; Nervi C
    Blood; 2007 May; 109(10):4432-40. PubMed ID: 17244680
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Characterization of the chimeric retinoic acid receptor RARalpha/VDR.
    Pemrick SM; Abarzúa P; Kratzeisen C; Marks MS; Medin JA; Ozato K; Grippo JF
    Leukemia; 1998 Apr; 12(4):554-62. PubMed ID: 9557614
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Role of the histone deacetylase complex in acute promyelocytic leukaemia.
    Lin RJ; Nagy L; Inoue S; Shao W; Miller WH; Evans RM
    Nature; 1998 Feb; 391(6669):811-4. PubMed ID: 9486654
    [TBL] [Abstract][Full Text] [Related]  

  • 12. RARα2 and PML-RAR similarities in the control of basal and retinoic acid induced myeloid maturation of acute myeloid leukemia cells.
    Gianni M; Fratelli M; Bolis M; Kurosaki M; Zanetti A; Paroni G; Rambaldi A; Borleri G; Rochette-Egly C; Terao M; Garattini E
    Oncotarget; 2017 Jun; 8(23):37041-37060. PubMed ID: 27419624
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Translocation products in acute myeloid leukemia activate the Wnt signaling pathway in hematopoietic cells.
    Müller-Tidow C; Steffen B; Cauvet T; Tickenbrock L; Ji P; Diederichs S; Sargin B; Köhler G; Stelljes M; Puccetti E; Ruthardt M; deVos S; Hiebert SW; Koeffler HP; Berdel WE; Serve H
    Mol Cell Biol; 2004 Apr; 24(7):2890-904. PubMed ID: 15024077
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Differential changes of retinoid-X-receptor (RXR alpha) and its RAR alpha and PML-RAR alpha partners induced by retinoic acid and cAMP distinguish maturation sensitive and resistant t(15;17) promyelocytic leukemia NB4 cells.
    Duprez E; Lillehaug JR; Gaub MP; Lanotte M
    Oncogene; 1996 Jun; 12(11):2443-50. PubMed ID: 8649786
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Targeting AML1/ETO-histone deacetylase repressor complex: a novel mechanism for valproic acid-mediated gene expression and cellular differentiation in AML1/ETO-positive acute myeloid leukemia cells.
    Liu S; Klisovic RB; Vukosavljevic T; Yu J; Paschka P; Huynh L; Pang J; Neviani P; Liu Z; Blum W; Chan KK; Perrotti D; Marcucci G
    J Pharmacol Exp Ther; 2007 Jun; 321(3):953-60. PubMed ID: 17389244
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Histone deacetylase-targeted treatment restores retinoic acid signaling and differentiation in acute myeloid leukemia.
    Ferrara FF; Fazi F; Bianchini A; Padula F; Gelmetti V; Minucci S; Mancini M; Pelicci PG; Lo Coco F; Nervi C
    Cancer Res; 2001 Jan; 61(1):2-7. PubMed ID: 11196162
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The methyl-CpG binding protein MBD1 is required for PML-RARalpha function.
    Villa R; Morey L; Raker VA; Buschbeck M; Gutierrez A; De Santis F; Corsaro M; Varas F; Bossi D; Minucci S; Pelicci PG; Di Croce L
    Proc Natl Acad Sci U S A; 2006 Jan; 103(5):1400-5. PubMed ID: 16432238
    [TBL] [Abstract][Full Text] [Related]  

  • 18. AML-1/ETO fusion protein is a dominant negative inhibitor of transcriptional repression by the promyelocytic leukemia zinc finger protein.
    Melnick A; Carlile GW; McConnell MJ; Polinger A; Hiebert SW; Licht JD
    Blood; 2000 Dec; 96(12):3939-47. PubMed ID: 11090081
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Histone deacetylase inhibition improves dendritic cell differentiation of leukemic blasts with AML1-containing fusion proteins.
    Moldenhauer A; Frank RC; Pinilla-Ibarz J; Holland G; Boccuni P; Scheinberg DA; Salama A; Seeger K; Moore MA; Nimer SD
    J Leukoc Biol; 2004 Sep; 76(3):623-33. PubMed ID: 15197237
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Regulation of vitamin D receptor expression by retinoic acid receptor alpha in acute myeloid leukemia cells.
    Marchwicka A; Cebrat M; Łaszkiewicz A; Śnieżewski Ł; Brown G; Marcinkowska E
    J Steroid Biochem Mol Biol; 2016 May; 159():121-30. PubMed ID: 26969398
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.