280 related articles for article (PubMed ID: 12464253)
1. Ovine steroid 17alpha-hydroxylase cytochrome P450: characteristics of the hydroxylase and lyase activities of the adrenal cortex enzyme.
Swart P; Lombard N; Swart AC; van der Merwe T; Murry BA; Nicol M; Ian Mason J
Arch Biochem Biophys; 2003 Jan; 409(1):145-52. PubMed ID: 12464253
[TBL] [Abstract][Full Text] [Related]
2. Baboon cytochrome P450 17alpha-hydroxylase/17,20-lyase (CYP17).
Swart AC; Kolar NW; Lombard N; Mason JI; Swart P
Eur J Biochem; 2002 Nov; 269(22):5608-16. PubMed ID: 12423360
[TBL] [Abstract][Full Text] [Related]
3. Kinetic processivity of the two-step oxidations of progesterone and pregnenolone to androgens by human cytochrome P450 17A1.
Gonzalez E; Guengerich FP
J Biol Chem; 2017 Aug; 292(32):13168-13185. PubMed ID: 28684414
[TBL] [Abstract][Full Text] [Related]
4. Cortisol production in sheep is influenced by the functional expression of two cytochrome P450 17α-hydroxylase/17,20-lyase (CYP17) isoforms.
Hough D; Cloete SW; Storbeck K; Swart AC; Swart P
J Anim Sci; 2013 Mar; 91(3):1193-206. PubMed ID: 23243163
[TBL] [Abstract][Full Text] [Related]
5. Cytochrome b(5) modulation of 17{alpha} hydroxylase and 17-20 lyase (CYP17) activities in steroidogenesis.
Akhtar MK; Kelly SL; Kaderbhai MA
J Endocrinol; 2005 Nov; 187(2):267-74. PubMed ID: 16293774
[TBL] [Abstract][Full Text] [Related]
6. Xenopus laevis CYP17 regulates androgen biosynthesis independent of the cofactor cytochrome b5.
Yang WH; Hammes SR
J Biol Chem; 2005 Mar; 280(11):10196-201. PubMed ID: 15640159
[TBL] [Abstract][Full Text] [Related]
7. Progesterone 16 alpha-hydroxylase activity is catalyzed by human cytochrome P450 17 alpha-hydroxylase.
Swart P; Swart AC; Waterman MR; Estabrook RW; Mason JI
J Clin Endocrinol Metab; 1993 Jul; 77(1):98-102. PubMed ID: 8325965
[TBL] [Abstract][Full Text] [Related]
8. A single amino acid residue, Ala 105, confers 16alpha-hydroxylase activity to human cytochrome P450 17alpha-hydroxylase/17,20 lyase.
Swart AC; Storbeck KH; Swart P
J Steroid Biochem Mol Biol; 2010 Apr; 119(3-5):112-20. PubMed ID: 20043997
[TBL] [Abstract][Full Text] [Related]
9. Conversion of pregnenolone to DHEA by human 17alpha-hydroxylase/17, 20-lyase (P450c17). Evidence that DHEA is produced from the released intermediate, 17alpha-hydroxypregnenolone.
Soucy P; Luu-The V
Eur J Biochem; 2000 Jun; 267(11):3243-7. PubMed ID: 10824109
[TBL] [Abstract][Full Text] [Related]
10. P450c17 mutations R347H and R358Q selectively disrupt 17,20-lyase activity by disrupting interactions with P450 oxidoreductase and cytochrome b5.
Geller DH; Auchus RJ; Miller WL
Mol Endocrinol; 1999 Jan; 13(1):167-75. PubMed ID: 9892022
[TBL] [Abstract][Full Text] [Related]
11. CYP17 mutation E305G causes isolated 17,20-lyase deficiency by selectively altering substrate binding.
Sherbet DP; Tiosano D; Kwist KM; Hochberg Z; Auchus RJ
J Biol Chem; 2003 Dec; 278(49):48563-9. PubMed ID: 14504283
[TBL] [Abstract][Full Text] [Related]
12. Modulation of the activity of human 17 alpha-hydroxylase-17,20-lyase (CYP17) by cytochrome b5: endocrinological and mechanistic implications.
Lee-Robichaud P; Wright JN; Akhtar ME; Akhtar M
Biochem J; 1995 Jun; 308 ( Pt 3)(Pt 3):901-8. PubMed ID: 8948449
[TBL] [Abstract][Full Text] [Related]
13. The effect of cytochrome b5 on progesterone metabolism in the ovine adrenal.
Swart P; Engelbrecht Y; Bellstedt DU; de Villiers CA; Dreesbeimdieke C
Endocr Res; 1995; 21(1-2):297-306. PubMed ID: 7588393
[TBL] [Abstract][Full Text] [Related]
14. Hydroxylation and lyase reactions of steroids catalyzed by mouse cytochrome P450 17A1 (Cyp17a1).
Lee SG; Kim V; Lee GH; Kim C; Jeong E; Guengerich FP; Kim D
J Inorg Biochem; 2023 Mar; 240():112085. PubMed ID: 36640554
[TBL] [Abstract][Full Text] [Related]
15. Biochemical differences between rat and human cytochrome P450c17 support the different steroidogenic needs of these two species.
Brock BJ; Waterman MR
Biochemistry; 1999 Feb; 38(5):1598-606. PubMed ID: 9931027
[TBL] [Abstract][Full Text] [Related]
16. The 17, 20-lyase activity of cytochrome p450c17 from human fetal testis favors the delta5 steroidogenic pathway.
Flück CE; Miller WL; Auchus RJ
J Clin Endocrinol Metab; 2003 Aug; 88(8):3762-6. PubMed ID: 12915666
[TBL] [Abstract][Full Text] [Related]
17. Molecular cloning and heterologous expression in E. coli of cytochrome P45017alpha. Comparison of structural and functional properties of substrate-specific cytochromes P450 from different species.
Gilep AA; Estabrook RW; Usanov SA
Biochemistry (Mosc); 2003 Jan; 68(1):86-98. PubMed ID: 12693981
[TBL] [Abstract][Full Text] [Related]
18. Modulation of 17alpha-hydroxylase/17,20-lyase activity of guinea pig cytochrome P450c17 by site-directed mutagenesis.
Beaudoin C; Lavallée B; Tremblay Y; Hum DW; Breton R; de Launoit Y; Bélanger A
DNA Cell Biol; 1998 Aug; 17(8):707-15. PubMed ID: 9726253
[TBL] [Abstract][Full Text] [Related]
19. Corticosteroid Biosynthesis Revisited: No Direct Hydroxylation of Pregnenolone by Steroid 21-Hydroxylase.
Loke S; Stoll A; Machalz D; Botrè F; Wolber G; Bureik M; Parr MK
Front Endocrinol (Lausanne); 2021; 12():633785. PubMed ID: 34149610
[TBL] [Abstract][Full Text] [Related]
20. Some enzymatic vagaries of a bovine adrenal microsomal cytochrome P-450 introduced and expressed in transformed monkey kidney cells.
Estabrook RW; Mason JI; Martin-Wixtrom C; Zuber M; Waterman MR
Prog Clin Biol Res; 1988; 274():525-40. PubMed ID: 3406037
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
