BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

344 related articles for article (PubMed ID: 12466885)

  • 1. Construction of engineered CHO strains for high-level production of recombinant proteins.
    Kito M; Itami S; Fukano Y; Yamana K; Shibui T
    Appl Microbiol Biotechnol; 2002 Dec; 60(4):442-8. PubMed ID: 12466885
    [TBL] [Abstract][Full Text] [Related]  

  • 2. [Development of site-specific integration system to high-level expression recombinant proteins in CHO cells].
    Zhou H; Liu ZG; Sun ZW; Yu WY
    Sheng Wu Gong Cheng Xue Bao; 2007 Jul; 23(4):756-62. PubMed ID: 17822058
    [TBL] [Abstract][Full Text] [Related]  

  • 3. An efficient and targeted gene integration system for high-level antibody expression.
    Huang Y; Li Y; Wang YG; Gu X; Wang Y; Shen BF
    J Immunol Methods; 2007 Apr; 322(1-2):28-39. PubMed ID: 17350648
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Generation of stable cell lines by site-specific integration of transgenes into engineered Chinese hamster ovary strains using an FLP-FRT system.
    Zhou H; Liu ZG; Sun ZW; Huang Y; Yu WY
    J Biotechnol; 2010 May; 147(2):122-9. PubMed ID: 20371256
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A novel RNA silencing vector to improve antigen expression and stability in Chinese hamster ovary cells.
    Hong WW; Wu SC
    Vaccine; 2007 May; 25(20):4103-11. PubMed ID: 17428585
    [TBL] [Abstract][Full Text] [Related]  

  • 6. [Significantly improvement of antibody expression level in CHO cells through downregulation of the DHFR gene in expression vector].
    Bai Y; Wang Y; Zhang HR; Zhou LJ; Lu YQ; Yu LZ
    Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi; 2003 Jan; 19(1):62-4, 67. PubMed ID: 15132910
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Key determinants in the occurrence of clonal variation in humanized antibody expression of cho cells during dihydrofolate reductase mediated gene amplification.
    Kim NS; Byun TH; Lee GM
    Biotechnol Prog; 2001; 17(1):69-75. PubMed ID: 11170482
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Characterization of chimeric antibody producing CHO cells in the course of dihydrofolate reductase-mediated gene amplification and their stability in the absence of selective pressure.
    Kim SJ; Kim NS; Ryu CJ; Hong HJ; Lee GM
    Biotechnol Bioeng; 1998 Apr; 58(1):73-84. PubMed ID: 10099263
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cytogenetic analysis of chimeric antibody-producing CHO cells in the course of dihydrofolate reductase-mediated gene amplification and their stability in the absence of selective pressure.
    Kim SJ; Lee GM
    Biotechnol Bioeng; 1999 Sep; 64(6):741-9. PubMed ID: 10417224
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Expression of chimeric antibody in mammalian cells using dicistronic expression vector.
    Xiong KH; Liang QC; Xiong H; Zou CX; Gao GD; Zhao ZW; Zhang H
    Biotechnol Lett; 2005 Nov; 27(21):1713-7. PubMed ID: 16247680
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Transfection of a nonactive site mutant murine DHFR cDNA (the tryptophan 15 mutant) into Chinese hamster ovary and mouse marrow progenitor cells imparts MTX resistance in vitro.
    Banerjee D; Zhao SC; Tong Y; Steinherz J; Gritsman K; Bertino JR
    Cancer Gene Ther; 1994 Sep; 1(3):181-4. PubMed ID: 7621249
    [TBL] [Abstract][Full Text] [Related]  

  • 12. High-throughput clonal selection of recombinant CHO cells using a dominant selectable and amplifiable metallothionein-GFP fusion protein.
    Bailey CG; Tait AS; Sunstrom NA
    Biotechnol Bioeng; 2002 Dec; 80(6):670-6. PubMed ID: 12378608
    [TBL] [Abstract][Full Text] [Related]  

  • 13. [Expression of human-mouse chimeric antibody ch-BD1 and its affinity to human bladder cancer in vitro and in vivo].
    Bai Y; Yu LZ; Lü YQ; Ai JK; Zhou LJ; Zhang CL; Wang Y
    Zhonghua Yi Xue Za Zhi; 2003 Feb; 83(4):333-7. PubMed ID: 12812655
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification and analysis of specific chromosomal region adjacent to exogenous Dhfr-amplified region in Chinese hamster ovary cell genome.
    Park JY; Takagi Y; Yamatani M; Honda K; Asakawa S; Shimizu N; Omasa T; Ohtake H
    J Biosci Bioeng; 2010 May; 109(5):504-11. PubMed ID: 20347775
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Development of a Chinese hamster ovary cell line for recombinant adenovirus-mediated gene expression.
    Condon RG; Schaefer EJ; Santoro M; Longley R; Tsao YS; Zurawski SM; Liu Z
    Biotechnol Prog; 2003; 19(1):137-43. PubMed ID: 12573016
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Overexpression of human prothrombin in permanent cell lines using a dominant selection/amplification fusion marker.
    Herlitschka SE; Falkner FG; Schlokat U; Dorner F
    Protein Expr Purif; 1996 Nov; 8(3):358-64. PubMed ID: 8936598
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The isolation of CHO cells with a site conferring a high and reproducible transgene amplification rate.
    Cacciatore JJ; Leonard EF; Chasin LA
    J Biotechnol; 2012 Dec; 164(2):346-53. PubMed ID: 23376841
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Generation of high-expressing cells by methotrexate amplification of destabilized dihydrofolate reductase selection marker.
    Ng SK
    Methods Mol Biol; 2012; 801():161-72. PubMed ID: 21987253
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Clonal variability within dihydrofolate reductase-mediated gene amplified Chinese hamster ovary cells: stability in the absence of selective pressure.
    Kim NS; Kim SJ; Lee GM
    Biotechnol Bioeng; 1998 Dec; 60(6):679-88. PubMed ID: 10099478
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Gene amplification and vector engineering to achieve rapid and high-level therapeutic protein production using the Dhfr-based CHO cell selection system.
    Cacciatore JJ; Chasin LA; Leonard EF
    Biotechnol Adv; 2010; 28(6):673-81. PubMed ID: 20416368
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.