These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

277 related articles for article (PubMed ID: 12467212)

  • 1. Identification of a novel synthetic triterpenoid, methyl-2-cyano-3,12-dioxooleana-1,9-dien-28-oate, that potently induces caspase-mediated apoptosis in human lung cancer cells.
    Kim KB; Lotan R; Yue P; Sporn MB; Suh N; Gribble GW; Honda T; Wu GS; Hong WK; Sun SY
    Mol Cancer Ther; 2002 Jan; 1(3):177-84. PubMed ID: 12467212
    [TBL] [Abstract][Full Text] [Related]  

  • 2. c-Jun NH2-terminal kinase-mediated up-regulation of death receptor 5 contributes to induction of apoptosis by the novel synthetic triterpenoid methyl-2-cyano-3,12-dioxooleana-1, 9-dien-28-oate in human lung cancer cells.
    Zou W; Liu X; Yue P; Zhou Z; Sporn MB; Lotan R; Khuri FR; Sun SY
    Cancer Res; 2004 Oct; 64(20):7570-8. PubMed ID: 15492284
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The novel triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid (CDDO) potently enhances apoptosis induced by tumor necrosis factor in human leukemia cells.
    Stadheim TA; Suh N; Ganju N; Sporn MB; Eastman A
    J Biol Chem; 2002 May; 277(19):16448-55. PubMed ID: 11880365
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Depletion of intracellular glutathione contributes to JNK-mediated death receptor 5 upregulation and apoptosis induction by the novel synthetic triterpenoid methyl-2-cyano-3, 12-dioxooleana-1, 9-dien-28-oate (CDDO-Me).
    Yue P; Zhou Z; Khuri FR; Sun SY
    Cancer Biol Ther; 2006 May; 5(5):492-7. PubMed ID: 16582599
    [TBL] [Abstract][Full Text] [Related]  

  • 5. c-FLIP downregulation contributes to apoptosis induction by the novel synthetic triterpenoid methyl-2-cyano-3, 12-dioxooleana-1, 9-dien-28-oate (CDDO-Me) in human lung cancer cells.
    Zou W; Chen S; Liu X; Yue P; Sporn MB; Khuri FR; Sun SY
    Cancer Biol Ther; 2007 Oct; 6(10):1614-20. PubMed ID: 18253090
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Novel triterpenoid CDDO-Me is a potent inducer of apoptosis and differentiation in acute myelogenous leukemia.
    Konopleva M; Tsao T; Ruvolo P; Stiouf I; Estrov Z; Leysath CE; Zhao S; Harris D; Chang S; Jackson CE; Munsell M; Suh N; Gribble G; Honda T; May WS; Sporn MB; Andreeff M
    Blood; 2002 Jan; 99(1):326-35. PubMed ID: 11756188
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Apoptotic activity and mechanism of 2-cyano-3,12-dioxoolean-1,9-dien-28-oic-acid and related synthetic triterpenoids in prostate cancer.
    Hyer ML; Shi R; Krajewska M; Meyer C; Lebedeva IV; Fisher PB; Reed JC
    Cancer Res; 2008 Apr; 68(8):2927-33. PubMed ID: 18413762
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid induces caspase-dependent and -independent apoptosis in acute myelogenous leukemia.
    Konopleva M; Tsao T; Estrov Z; Lee RM; Wang RY; Jackson CE; McQueen T; Monaco G; Munsell M; Belmont J; Kantarjian H; Sporn MB; Andreeff M
    Cancer Res; 2004 Nov; 64(21):7927-35. PubMed ID: 15520199
    [TBL] [Abstract][Full Text] [Related]  

  • 9. CDDO-me induces apoptosis and inhibits Akt, mTOR and NF-kappaB signaling proteins in prostate cancer cells.
    Deeb D; Gao X; Dulchavsky SA; Gautam SC
    Anticancer Res; 2007; 27(5A):3035-44. PubMed ID: 17970042
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The novel triterpenoid 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid induces apoptosis of human myeloid leukemia cells by a caspase-8-dependent mechanism.
    Ito Y; Pandey P; Place A; Sporn MB; Gribble GW; Honda T; Kharbanda S; Kufe D
    Cell Growth Differ; 2000 May; 11(5):261-7. PubMed ID: 10845427
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The novel triterpenoid CDDO induces apoptosis and differentiation of human osteosarcoma cells by a caspase-8 dependent mechanism.
    Ito Y; Pandey P; Sporn MB; Datta R; Kharbanda S; Kufe D
    Mol Pharmacol; 2001 May; 59(5):1094-9. PubMed ID: 11306692
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Oleanane triterpenoid CDDO-Me induces apoptosis in multidrug resistant osteosarcoma cells through inhibition of Stat3 pathway.
    Ryu K; Susa M; Choy E; Yang C; Hornicek FJ; Mankin HJ; Duan Z
    BMC Cancer; 2010 May; 10():187. PubMed ID: 20459702
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Casticin induces caspase-mediated apoptosis via activation of mitochondrial pathway and upregulation of DR5 in human lung cancer cells.
    Zhou Y; Peng Y; Mao QQ; Li X; Chen MW; Su J; Tian L; Mao NQ; Long LZ; Quan MF; Liu F; Zhou SF; Zhao YX
    Asian Pac J Trop Med; 2013 May; 6(5):372-8. PubMed ID: 23608376
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Coupling of endoplasmic reticulum stress to CDDO-Me-induced up-regulation of death receptor 5 via a CHOP-dependent mechanism involving JNK activation.
    Zou W; Yue P; Khuri FR; Sun SY
    Cancer Res; 2008 Sep; 68(18):7484-92. PubMed ID: 18794136
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthetic oleanane triterpenoid, CDDO-Me, induces apoptosis in ovarian cancer cells by inhibiting prosurvival AKT/NF-κB/mTOR signaling.
    Gao X; Liu Y; Deeb D; Arbab AS; Guo AM; Dulchavsky SA; Gautam SC
    Anticancer Res; 2011 Nov; 31(11):3673-81. PubMed ID: 22110186
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Oleanane triterpenoid CDDO-Me inhibits growth and induces apoptosis in prostate cancer cells by independently targeting pro-survival Akt and mTOR.
    Deeb D; Gao X; Jiang H; Dulchavsky SA; Gautam SC
    Prostate; 2009 Jun; 69(8):851-60. PubMed ID: 19189297
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Bardoxolone methyl induces apoptosis and autophagy and inhibits epithelial-to-mesenchymal transition and stemness in esophageal squamous cancer cells.
    Wang YY; Yang YX; Zhao R; Pan ST; Zhe H; He ZX; Duan W; Zhang X; Yang T; Qiu JX; Zhou SF
    Drug Des Devel Ther; 2015; 9():993-1026. PubMed ID: 25733817
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthetic triterpenoids inhibit growth, induce apoptosis and suppress pro-survival Akt, mTOR and NF-{kappa}B signaling proteins in colorectal cancer cells.
    Gao X; Deeb D; Hao J; Liu Y; Arbab AS; Dulchavsky SA; Gautam SC
    Anticancer Res; 2010 Mar; 30(3):785-92. PubMed ID: 20392997
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Phytosphingosine induces apoptotic cell death via caspase 8 activation and Bax translocation in human cancer cells.
    Park MT; Kang JA; Choi JA; Kang CM; Kim TH; Bae S; Kang S; Kim S; Choi WI; Cho CK; Chung HY; Lee YS; Lee SJ
    Clin Cancer Res; 2003 Feb; 9(2):878-85. PubMed ID: 12576463
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Chemotherapy triggers apoptosis in a caspase-8-dependent and mitochondria-controlled manner in the non-small cell lung cancer cell line NCI-H460.
    Ferreira CG; Span SW; Peters GJ; Kruyt FA; Giaccone G
    Cancer Res; 2000 Dec; 60(24):7133-41. PubMed ID: 11156422
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.