BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

148 related articles for article (PubMed ID: 12472881)

  • 1. Altered processing of amyloid precursor protein in the human neuroblastoma SH-SY5Y by chronic hypoxia.
    Webster NJ; Green KN; Peers C; Vaughan PF
    J Neurochem; 2002 Dec; 83(6):1262-71. PubMed ID: 12472881
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Altered processing of the amyloid precursor protein and decreased expression of ADAM 10 by chronic hypoxia in SH-SY5Y: no role for the stress-activated JNK and p38 signalling pathways.
    Webster NJ; Green KN; Settle VJ; Peers C; Vaughan PF
    Brain Res Mol Brain Res; 2004 Nov; 130(1-2):161-9. PubMed ID: 15519686
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Chronic hypoxia in the human neuroblastoma SH-SY5Y causes reduced expression of the putative alpha-secretases, ADAM10 and TACE, without altering their mRNA levels.
    Marshall AJ; Rattray M; Vaughan PF
    Brain Res; 2006 Jul; 1099(1):18-24. PubMed ID: 16762326
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Atorvastatin-induced activation of Alzheimer's alpha secretase is resistant to standard inhibitors of protein phosphorylation-regulated ectodomain shedding.
    Parvathy S; Ehrlich M; Pedrini S; Diaz N; Refolo L; Buxbaum JD; Bogush A; Petanceska S; Gandy S
    J Neurochem; 2004 Aug; 90(4):1005-10. PubMed ID: 15287907
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Huperzine A regulates amyloid precursor protein processing via protein kinase C and mitogen-activated protein kinase pathways in neuroblastoma SK-N-SH cells over-expressing wild type human amyloid precursor protein 695.
    Peng Y; Lee DY; Jiang L; Ma Z; Schachter SC; Lemere CA
    Neuroscience; 2007 Dec; 150(2):386-95. PubMed ID: 17945434
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Proteasome-mediated effects on amyloid precursor protein processing at the gamma-secretase site.
    Flood F; Murphy S; Cowburn RF; Lannfelt L; Walker B; Johnston JA
    Biochem J; 2005 Jan; 385(Pt 2):545-50. PubMed ID: 15473868
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Muscarine enhances soluble amyloid precursor protein secretion in human neuroblastoma SH-SY5Y by a pathway dependent on protein kinase C(alpha), src-tyrosine kinase and extracellular signal-regulated kinase but not phospholipase C.
    Canet-Aviles RM; Anderton M; Hooper NM; Turner AJ; Vaughan PF
    Brain Res Mol Brain Res; 2002 Jun; 102(1-2):62-72. PubMed ID: 12191495
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Amyloid precursor protein compartmentalization restricts beta-amyloid production: therapeutic targets based on BACE compartmentalization.
    Gandhi S; Refolo LM; Sambamurti K
    J Mol Neurosci; 2004; 24(1):137-43. PubMed ID: 15314262
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Nicergoline stimulates protein kinase C mediated alpha-secretase processing of the amyloid precursor protein in cultured human neuroblastoma SH-SY5Y cells.
    Cedazo-Minguez A; Bonecchi L; Winblad B; Post C; Wong EH; Cowburn RF; Benatti L
    Neurochem Int; 1999 Oct; 35(4):307-15. PubMed ID: 10482351
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Caspase cleaved presenilin-1 is part of active gamma-secretase complexes.
    Hansson CA; Popescu BO; Laudon H; Cedazo-Minguez A; Popescu LM; Winblad B; Ankarcrona M
    J Neurochem; 2006 Apr; 97(2):356-64. PubMed ID: 16539675
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Phosphorylation of amyloid precursor carboxy-terminal fragments enhances their processing by a gamma-secretase-dependent mechanism.
    Vingtdeux V; Hamdane M; Gompel M; Bégard S; Drobecq H; Ghestem A; Grosjean ME; Kostanjevecki V; Grognet P; Vanmechelen E; Buée L; Delacourte A; Sergeant N
    Neurobiol Dis; 2005 Nov; 20(2):625-37. PubMed ID: 15936948
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The phosphatidylinositol 3-kinase inhibitor wortmannin alters the metabolism of the Alzheimer's amyloid precursor protein.
    Petanceska SS; Gandy S
    J Neurochem; 1999 Dec; 73(6):2316-20. PubMed ID: 10582589
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cleavage of Alzheimer's amyloid precursor protein by alpha-secretase occurs at the surface of neuronal cells.
    Parvathy S; Hussain I; Karran EH; Turner AJ; Hooper NM
    Biochemistry; 1999 Jul; 38(30):9728-34. PubMed ID: 10423252
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Salidroside attenuates hypoxia-induced abnormal processing of amyloid precursor protein by decreasing BACE1 expression in SH-SY5Y cells.
    Li QY; Wang HM; Wang ZQ; Ma JF; Ding JQ; Chen SD
    Neurosci Lett; 2010 Sep; 481(3):154-8. PubMed ID: 20599477
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Tenuigenin treatment decreases secretion of the Alzheimer's disease amyloid beta-protein in cultured cells.
    Jia H; Jiang Y; Ruan Y; Zhang Y; Ma X; Zhang J; Beyreuther K; Tu P; Zhang D
    Neurosci Lett; 2004 Aug; 367(1):123-8. PubMed ID: 15308312
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Processing of the Alzheimer's disease amyloid precursor protein in Pichia pastoris: immunodetection of alpha-, beta-, and gamma-secretase products.
    Le Brocque D; Henry A; Cappai R; Li QX; Tanner JE; Galatis D; Gray C; Holmes S; Underwood JR; Beyreuther K; Masters CL; Evin G
    Biochemistry; 1998 Oct; 37(42):14958-65. PubMed ID: 9778373
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The thiol proteinase inhibitor E-64-d ameliorates amyloid-β-induced reduction of sAPPα secretion by reversing ceramide-induced protein kinase C down-regulation in SH-SY5Y neuroblastoma cells.
    Tanabe F; Nakajima T; Ito M
    Biochem Biophys Res Commun; 2013 Nov; 441(1):256-61. PubMed ID: 24141119
    [TBL] [Abstract][Full Text] [Related]  

  • 18. PPAR-α agonist regulates amyloid-β generation via inhibiting BACE-1 activity in human neuroblastoma SH-SY5Y cells transfected with APPswe gene.
    Zhang H; Gao Y; Qiao PF; Zhao FL; Yan Y
    Mol Cell Biochem; 2015 Oct; 408(1-2):37-46. PubMed ID: 26092426
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Targeting ADAM10 to lipid rafts in neuroblastoma SH-SY5Y cells impairs amyloidogenic processing of the amyloid precursor protein.
    Harris B; Pereira I; Parkin E
    Brain Res; 2009 Nov; 1296():203-15. PubMed ID: 19679113
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Activity of alpha-secretase as the common final effector of protein kinase C-dependent and -independent modulation of amyloid precursor protein metabolism.
    Racchi M; Solano DC; Sironi M; Govoni S
    J Neurochem; 1999 Jun; 72(6):2464-70. PubMed ID: 10349856
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.